Results 341 to 350 of about 448,615 (401)

Activating AMPK improves pathological phenotypes due to mtDNA depletion

open access: yesThe FEBS Journal, Volume 292, Issue 9, Page 2359-2380, May 2025.
In a cellular model of mitochondrial disease characterized by progressive mitochondrial DNA (mtDNA) depletion, we found that advancing mitochondrial dysfunction triggers the early and specific activation of the mitochondria‐associated pool of AMP‐activated protein kinase (AMPK), a master regulator of energy homeostasis.
Gustavo Carvalho   +14 more
wiley   +1 more source

Lithium chloride corrects weakness and myopathology in a preclinical model of LGMD1D [PDF]

open access: yes, 2019
Bengoechea, Rocio   +5 more
core   +1 more source

From Stress to Success: Strategies for Improving Heat Tolerance in Wheat

open access: yesJournal of Agronomy and Crop Science, Volume 211, Issue 3, May 2025.
ABSTRACT Wheat, a major staple crop, is critical for global food security. However, abiotic stresses, particularly heat stress, threaten crop productivity. With climate change predicted to increase temperatures by around 1.5°C by 2050, crop productivity could be severely affected.
Muhammad Ahmad   +8 more
wiley   +1 more source

Allele Frequencies and Genotypes for the Ryanodine Receptor 1 Variant Causing Malignant Hyperthermia and Fatal Rhabdomyolysis With Hyperthermia in Horses

open access: yesJournal of Veterinary Internal Medicine, Volume 39, Issue 3, May/June 2025.
ABSTRACT Background Fatal anesthesia‐induced malignant hyperthermia (MH) and rhabdomyolysis with hyperthermia documented in Quarter Horses (QH) breeds are caused by a missense variant in the ryanodine receptor 1 gene (RYR1: XP_023505430.1.:p.(R2454G), designated as MH).
Monica Aleman   +2 more
wiley   +1 more source

Pollution, stress response, and obesity: A systematic review

open access: yesObesity Reviews, Volume 26, Issue 5, May 2025.
Summary Limited literature addresses the association between pollution, stress, and obesity, and knowledge synthesis on the associations between these three topics has yet to be made. Two reviewers independently conducted a systematic review of MEDLINE, Embase, and Web of Science Core Collection databases to identify studies dealing with the effects of
Sandra El Kouche   +7 more
wiley   +1 more source

BR signalling haplotypes contribute to indica–japonica differentiation for grain yield and quality in rice

open access: yesPlant Biotechnology Journal, Volume 23, Issue 5, Page 1618-1636, May 2025.
Summary The functional difference of natural variations in conserved BR signalling genes and the genetic basis of rice indica–japonica differentiation are important yet unknown. Here, we discovered natural variations of the four key components (OsBRI1, OsBAK1, OsGSK3 and OsBZR1) in BR signalling pathway by GWAS using an indicator of indica–japonica ...
Xinyi Yang   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy