Correction: Expression and inactivation of glycogen synthase kinase 3 alpha/ beta and their association with the expression of cyclin D1 and p53 in oral squamous cell carcinoma progression. [PDF]
Mishra R, Nagini S, Rana A.
europepmc +1 more source
Activating AMPK improves pathological phenotypes due to mtDNA depletion
In a cellular model of mitochondrial disease characterized by progressive mitochondrial DNA (mtDNA) depletion, we found that advancing mitochondrial dysfunction triggers the early and specific activation of the mitochondria‐associated pool of AMP‐activated protein kinase (AMPK), a master regulator of energy homeostasis.
Gustavo Carvalho+14 more
wiley +1 more source
Association of glycogen synthase kinase-3β with cognitive impairment in type 2 diabetes patients: a six-year follow-up study. [PDF]
Wei W+8 more
europepmc +1 more source
Lithium chloride corrects weakness and myopathology in a preclinical model of LGMD1D [PDF]
Bengoechea, Rocio+5 more
core +1 more source
From Stress to Success: Strategies for Improving Heat Tolerance in Wheat
ABSTRACT Wheat, a major staple crop, is critical for global food security. However, abiotic stresses, particularly heat stress, threaten crop productivity. With climate change predicted to increase temperatures by around 1.5°C by 2050, crop productivity could be severely affected.
Muhammad Ahmad+8 more
wiley +1 more source
Inhibition of mitochondrial cyclophilin D, a downstream target of glycogen synthase kinase 3α, improves sperm motility. [PDF]
Park SH, Gye MC.
europepmc +1 more source
ABSTRACT Background Fatal anesthesia‐induced malignant hyperthermia (MH) and rhabdomyolysis with hyperthermia documented in Quarter Horses (QH) breeds are caused by a missense variant in the ryanodine receptor 1 gene (RYR1: XP_023505430.1.:p.(R2454G), designated as MH).
Monica Aleman+2 more
wiley +1 more source
Pollution, stress response, and obesity: A systematic review
Summary Limited literature addresses the association between pollution, stress, and obesity, and knowledge synthesis on the associations between these three topics has yet to be made. Two reviewers independently conducted a systematic review of MEDLINE, Embase, and Web of Science Core Collection databases to identify studies dealing with the effects of
Sandra El Kouche+7 more
wiley +1 more source
Regulation of Phosphorylation of Glycogen Synthase Kinase 3α and the Correlation with Sperm Motility in Human. [PDF]
Park SH+5 more
europepmc +1 more source
Summary The functional difference of natural variations in conserved BR signalling genes and the genetic basis of rice indica–japonica differentiation are important yet unknown. Here, we discovered natural variations of the four key components (OsBRI1, OsBAK1, OsGSK3 and OsBZR1) in BR signalling pathway by GWAS using an indicator of indica–japonica ...
Xinyi Yang+7 more
wiley +1 more source