Results 71 to 80 of about 448,615 (401)
Metabolic crosstalk: molecular links between glycogen and lipid metabolism in obesity. [PDF]
, 2014 Glycogen and lipids are major storage forms of energy that are tightly regulated by hormones and metabolic signals. We demonstrate that feeding mice a high-fat diet (HFD) increases hepatic glycogen due to increased expression of the glycogenic ...
Bridges, Dave +12 more
core +2 more sources
Diffusion properties of single FoF1-ATP synthases in a living bacterium unraveled by localization microscopy [PDF]
, 2012 FoF1-ATP synthases in Escherichia coli (E. coli) bacteria are membrane-bound enzymes which use an internal proton-driven rotary double motor to catalyze the synthesis of adenosine triphosphate (ATP). According to the 'chemiosmotic hypothesis', a series of proton pumps generate the necessary pH difference plus an electric potential across the bacterial ...
arxiv +1 more source
Rag GTPases are cardioprotective by regulating lysosomal function. [PDF]
, 2014 The Rag family proteins are Ras-like small GTPases that have a critical role in amino-acid-stimulated mTORC1 activation by recruiting mTORC1 to lysosome.
Guan, Kun-Liang +8 more
core +2 more sources
Leukemia, 2015 The rapid proliferation of myeloid leukemia cells is highly dependent on increased glucose metabolism. Through an unbiased metabolomics analysis of leukemia cells, we found that the glycogenic precursor UDP-D-glucose is pervasively upregulated, despite ...
Haymanti Bhanot +15 more
semanticscholar +1 more source
Fluoride as a Potential Repressor of Glycogen Metabolism in Skeletal Muscle Cell Line CCL136
Molecules, 2023 The exposure of humans to fluorine is connected with its presence in the air, food and water. It is well known that fluorides even at a low concentration but with long time exposure accumulate in the body and lead to numerous metabolic disorders ...
Izabela Gutowska +7 more
doaj +1 more source
3D-localization microscopy and tracking of FoF1-ATP synthases in living bacteria [PDF]
, 2015 FoF1-ATP synthases are membrane-embedded protein machines that catalyze the synthesis of adenosine triphosphate. Using photoactivation-based localization microscopy (PALM) in TIR-illumination as well as structured illumination microscopy (SIM), we explore the spatial distribution and track single FoF1-ATP synthases in living E.
arxiv +1 more source
Activity And Localization Of Maltodextrin Binding Site Mutants Of Glycogen Synthase In Saccharomyces Cerevisiae [PDF]
, 2011 Mentor: Wayne A. WilsonGlycogen is a glucose polymer formed by the enzyme glycogen synthase and is used in many organisms to store chemical energy. Saccharomyces cerevisiae (baker’s yeast) was used to study the activity and localization of glycogen ...
Davis, Keri D., Slade, Stephen J.
core +1 more source
Is acetylation a metabolic rheostat that regulates skeletal muscle insulin action? [PDF]
, 2015 Skeletal muscle insulin resistance, which increases the risk for developing various metabolic diseases, including type 2 diabetes, is a common metabolic disorder in obesity and aging.
LaBarge, Samuel +2 more
core +2 more sources
Molecular Oncology, EarlyView.Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé +7 more
wiley +1 more source
Role of autophagy in glycogen breakdown and its relevance to chloroquine myopathy. [PDF]
PLoS Biology, 2013 Several myopathies are associated with defects in autophagic and lysosomal degradation of glycogen, but it remains unclear how glycogen is targeted to the lysosome and what significance this process has for muscle cells.
Jonathan Zirin +2 more
doaj +1 more source