Results 51 to 60 of about 82,991 (164)
Molecular Plant-Microbe Interactions, 2002 The phosphoglucomutase (pgm) gene codes for a key enzyme required for the formation of UDP-glucose and ADP-glucose, the sugar donors for the biosynthesis of glucose containing polysaccharides.
Viviana C. Lepek +5 more
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mTORC1 controls murine postprandial hepatic glycogen synthesis via Ppp1r3b
The Journal of Clinical InvestigationIn response to a meal, insulin drives hepatic glycogen synthesis to help regulate systemic glucose homeostasis. The mechanistic target of rapamycin complex 1 (mTORC1) is a well-established insulin target and contributes to the postprandial control of ...
Kahealani Uehara +12 more
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Deleterious effects of neuronal accumulation of glycogen in flies and mice
EMBO Molecular Medicine, 2012 Under physiological conditions, most neurons keep glycogen synthase (GS) in an inactive form and do not show detectable levels of glycogen. Nevertheless, aberrant glycogen accumulation in neurons is a hallmark of patients suffering from Lafora disease or
Jordi Duran +5 more
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Frontiers in Physiology, 2019 Harmonia axyridis is an important predatory insect and widely used in biological control of agricultural and forestry pests. Trehalose is directly involved in the energy storage of the H.
Yan Li +6 more
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Glycogen synthase kinase 3 controls migration of the neural crest lineage in mouse and Xenopus
Nature Communications, 2018 Defects in neural crest development cause neurocristopathies and cancer, but what regulates this is unclear. Here, the authors show that glycogen synthase kinase 3 (GSK3) regulates migration of neural crest cells, as shown on genetic deletion of GSK3 in ...
Sandra G. Gonzalez Malagon +10 more
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BMC Neuroscience, 2004 Background Lithium, a mood stabilizer widely used to treat bipolar disorder, also is a neuroprotectant, providing neurons protection from apoptosis induced by a broad spectrum of toxic conditions.
Jope Richard S, Zhou Tong, Song Ling
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CellsInterleukin 24 (IL-24) is a tumor-suppressing protein currently in clinical trials. We previously demonstrated that IL-24 leads to apoptosis in cancer cells through protein kinase A (PKA) activation in human breast cancer cells.
Anastassiya Kim +6 more
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Parasite, 2019 Glycogen synthase kinase 3 (GSK-3), which belongs to the serine/threonine kinase family, regulates glycogen metabolism, Wnt signaling, hormonal regulation, and embryonic development in many eukaryotes.
Rahman Md. Khalesur, You Myungjo
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Glycophagy is involved in cardiac glycogen regulation in response to exercise
Current Research in PhysiologyCardiac glycogen-autophagy (‘glycophagy’) is disturbed in cardiometabolic pathologies. The physiological role of cardiac glycophagy is unclear. Exercise induces transient cardiac glycogen accumulation.
Samuel L. James +7 more
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Effects of monochromatic light on hepatic glycogen and lipid synthesis in broilers
Poultry Science: Animal growth is closely related to glycolipid metabolism, and the liver is the main organ for glycogen storage and fat synthesis in birds, but whether monochromatic light affects glycogen and lipid synthesis in the liver is unclear. Therefore, in this
Lu Wang +3 more
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