Results 41 to 50 of about 82,991 (164)
Structural basis for 2′-phosphate incorporation into glycogen by glycogen synthase [PDF]
Proceedings of the National Academy of Sciences, 2013 Significance Glycogen is a branched glucose polymer found in most animals, fungi, bacteria, and archaea as an osmotically neutral means of energy storage. Glycogen also contains minor amounts of phosphate which can be removed by a dual specificity phosphatase, laforin.
Vimbai M, Chikwana +7 more
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Glycogen Metabolism and Its Role in Growth and Encystation in Entamoeba histolytica
Life, 2023 Entamoeba histolytica is a parasitic protozoan that causes diarrheal disease in approximately 100 million people worldwide every year. E. histolytica has two forms, the growing trophozoite and the infectious cyst.
Jordan Wesel, Cheryl Ingram-Smith
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Separation and Characterisation of Glycogen Synthase Kinase 3,Glycogen Synthase Kinase 4 and Glycogen Synthase Kinase 5 from Rabbit Skeletal Muscle [PDF]
European Journal of Biochemistry, 1982 Three glycogen synthase kinases termed glycogen synthase kinase 3, glycogen synthase kinase 4 and glycogen synthase kinase 5, which are distinct from cyclic‐AMP‐dependent protein kinase and phosphorylase kinase,have been purified and characterised. Their activities are unaffected by Ca2+, calmodulin, cyclic nucleotides and the inhibitor protein of ...
Cohen P +5 more
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Nuclear glycogen synthase — fact or artifact? [PDF]
FEBS Letters, 1982 According to Oron [FEBS Lett. (1980) 118, 255–258], nuclear glycogen synthase represents an artifact of preparation in rat liver nuclei. We investigated the nuclei isolated from in vitro growing HD33 ascites cells with exclusively cytoplasmic, and from in vivo growing HD33 Ehrlich—Lettré ascites tumor cells with mainly intranuclear, glycogen deposition.
Kopun, Marijana +2 more
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Journal of Parasitology Research, 2015 Trehalose and glycogen metabolism plays an important role in supporting life processes in many nematodes, including Anisakis simplex. Nematodes, cosmopolitan helminths parasitizing sea mammals and humans, cause a disease known as anisakiasis.
E. Łopieńska-Biernat +2 more
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Open MedicineTo explore the role of oxidative stress on glycogen synthase kinase-3 in lymphocytes of diabetes mellitus (DM) patients complicated with cerebral infarction (CI).
Wang Man +3 more
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Journal of Pharmacological Sciences, 2009 Glycogen synthase kinase-3β (GSK-3β) is a constitutively active kinase. Since its activation results in neurofibrillary tangle (NFT) deposits in aged and Alzheimer’s disease (AD) brains, GSK-3β may be inhibited under normal conditions but activated under
Akihiko Takashima
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Aeromonas surface glucan attached through the O-antigen ligase represents a new way to obtain UDP-glucose. [PDF]
PLoS ONE, 2012 We previously reported that A. hydrophila GalU mutants were still able to produce UDP-glucose introduced as a glucose residue in their lipopolysaccharide core. In this study, we found the unique origin of this UDP-glucose from a branched α-glucan surface
Susana Merino +5 more
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Nature Communications, 2016 It is not clear how circadian biochemical cascades are encoded into neural electrical signals. Here, using a combination of electrophysiology and modelling approaches in mice, the authors show activation of glycogen synthase kinase 3 modulates neural ...
Jodi R. Paul +5 more
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ORM Promotes Skeletal Muscle Glycogen Accumulation via CCR5-Activated AMPK Pathway in Mice
Frontiers in Pharmacology, 2016 We found previously that acute phase protein orosomucoid reacts to fatigue and activates C-C chemokine receptor type 5 to increase muscle glycogen storage and enhance muscle endurance (Lei et al., 2016). To explore the underlying molecular mechanisms, we
Zhen Qin +6 more
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