Results 31 to 40 of about 82,991 (164)

Glycogen metabolic genes are involved in trehalose-6-phosphate synthase-mediated regulation of pathogenicity by the rice blast fungus Magnaporthe oryzae.

PLoS Pathogens, 2013
The filamentous fungus Magnaporthe oryzae is the causal agent of rice blast disease. Here we show that glycogen metabolic genes play an important role in plant infection by M. oryzae.
Muhammad Badaruddin, Lucy J Holcombe, Richard A Wilson, Zheng-Yi Wang, Michael J Kershaw, Nicholas J Talbot   +5 more
doaj   +1 more source

Sevoflurane plays a reduced role in cognitive impairment compared with isoflurane: limited effect on fear memory retention

Neural Regeneration Research, 2020
Isoflurane and sevoflurane are both inhalation anesthetics, but in clinical application, sevoflurane has been considered to be less suitable for long-term anesthesia because of its catabolic compounds and potential nephrotoxicity.
Ying Du, Xiang-Dan Gong, Xin Fang, Fang Xing, Tian-Jiao Xia, Xiao-Ping Gu   +5 more
doaj   +1 more source

N6-methyladenosine modification governs liver glycogenesis by stabilizing the glycogen synthase 2 mRNA

Nature Communications, 2022
Here the authors find that the mRNA of GYS2, the liver-specific glycogen synthase, is a substrate of METTL3 and IGF2BP2 and that m6A-mediated regulation of Gys2 mRNA is critical for the maintenance of liver glycogenesis in mammals during growth, such as ...
Xiang Zhang, Huilong Yin, Xiaofang Zhang, Xunliang Jiang, Yongkang Liu, Haolin Zhang, Yingran Peng, Da Li, Yanping Yu, Jinbao Zhang, Shuli Cheng, Angang Yang, Rui Zhang   +12 more
doaj   +1 more source

Genome-wide identification and expression analysis of glycogen synthase kinase encoding genes in foxtail millet (Setaria italica L.) under salinity, dehydration, and oxidative stress

Plant Stress, 2023
Glycogen Synthase Kinase 3 (GSK3)/SHAGGY-like Kinase (SK) proteins in plants govern growth, development, and several abiotic and biotic stress responses.
Jawahar Singh, Vishal Varshney, Nisha Tak, Shweta Jha   +3 more
doaj   +1 more source

Identification and Characterization of GYS and GSK3β Provides Insights into the Regulation of Glycogen Synthesis in Jinjiang Oyster Crassostrea ariakensis

Fishes, 2023
Glycogen, a stored form of glucose, is an important form of energy for aquatic shellfish, contributing to the flavor and quality of the oyster. The glycogen synthase (GYS) and glycogen synthase kinase 3β (GSK3β) are two major enzymes in the glycogenesis.
Yan Wang, Zhihong Liu, Xi Chen, Liqing Zhou, Xiujun Sun, Tao Yu, Xiaomei Wang, Yanxin Zheng, Biao Wu   +8 more
doaj   +1 more source

Huddling alleviates the decrease in glycogen and lipid content in the liver of Brandt’s vole caused by mild cold environment [PDF]

Zoologia (Curitiba)
Low/cold ambient temperatures can induce hepatic damage in mammals, prompting the evolution of huddling as an adaptive strategy among small mammals to survive cold conditions in the wild.
Jin-Hui Xu, Lu-Fan Li, Xiao-Lu Zhang, Xiao-Tong Kong, Xing-Chen Wang, Li-Na Jiang, Zhe Wang   +6 more
doaj   +1 more source

Glycogen synthase activity in Candida albicans is partly controlled by the functional ortholog of Saccharomyces cerevisiae Gac1p

mSphere
To adapt to various host microenvironments, the human fungal pathogen Candida albicans possesses the capacity to accumulate and store glycogen as an internal carbohydrate source.
Jian Miao, David L. Williams, Michael D. Kruppa, Brian M. Peters   +3 more
doaj   +1 more source

Amaryllidaceae Alkaloids as Potential Glycogen Synthase Kinase-3β Inhibitors

Molecules, 2018
Glycogen synthase kinase-3β (GSK-3β) is a multifunctional serine/threonine protein kinase that was originally identified as an enzyme involved in the control of glycogen metabolism.
Daniela Hulcová, Kateřina Breiterová, Tomáš Siatka, Kamila Klímová, Lara Davani, Marcela Šafratová, Anna Hošťálková, Angela De Simone, Vincenza Andrisano, Lucie Cahlíková   +9 more
doaj   +1 more source

Shared control of hepatic glycogen synthesis by glycogen synthase and glucokinase [PDF]

Biochemical Journal, 2000
We have used recombinant adenoviruses (AdCMV-RLGS and AdCMV-GK) to overexpress the liver isoforms of glycogen synthase (GS) and glucokinase (GK) in primary cultured rat hepatocytes. Glucose activated overexpressed GS in a dose-dependent manner and caused the accumulation of larger amounts of glycogen in the AdCMV-RLGS-treated hepatocytes.
R R, Gomis, J C, Ferrer, J J, Guinovart
openaire   +2 more sources

Allosteric Regulation of Glycogen Synthase Controls Glycogen Synthesis in Muscle [PDF]

Cell Metabolism, 2010
Glycogen synthase (GS), a key enzyme in glycogen synthesis, is activated by the allosteric stimulator glucose-6-phosphate (G6P) and by dephosphorylation through inactivation of GS kinase-3 with insulin. The relative importance of these two regulatory mechanisms in controlling GS is not established, mainly due to the complex interplay between multiple ...
Bouskila, Michale, Hunter, Roger W., Ibrahim, Adel F.M., Delattre, Lucie, Peggie, Mark, Van Diepen, Janna A., Voshol, Peter J., Jensen, Jørgen, Sakamoto, Kei   +8 more
openaire   +4 more sources