Results 11 to 20 of about 82,991 (164)
Control of glycogen content in retina: allosteric regulation of glycogen synthase. [PDF]
PLoS ONE, 2012 Retinal tissue is exceptional because it shows a high level of energy metabolism. Glycogen content represents the only energy reserve in retina, but its levels are limited.
Ixchel Osorio-Paz +2 more
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Incorporation of phosphate into glycogen by glycogen synthase [PDF]
Archives of Biochemistry and Biophysics, 2016 The storage polymer glycogen normally contains small amounts of covalently attached phosphate as phosphomonoesters at C2, C3 and C6 atoms of glucose residues. In the absence of the laforin phosphatase, as in the rare childhood epilepsy Lafora disease, the phosphorylation level is elevated and is associated with abnormal glycogen structure that ...
Christopher J. Contreras +7 more
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Isozymes of glycogen synthase [PDF]
FEBS Letters, 1984 Antisera to rat skeletal muscle glycogen synthase failed to recognize liver glycogen synthase by electroblot analysis. The antisera recognized the enzyme in skeletal muscle, heart, fat, kidney, and brain. The results support the hypothesis that there are at least two isozymes of glycogen synthase, and that most tissues contain a form similar or ...
Kaslow, Harvey R., Lesikar, David D.
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Liver Glycogen Synthase in Rats with a Glycogen‐Storage Disorder [PDF]
European Journal of Biochemistry, 1980 1. A strain of rats with a genetically‐determined liver glycogen‐storage disorder (gsd/gsd) caused by a deficiency of liver phosphorylase kinase has a very high concentration of glycogen in the liver with a total glycogen synthase activity higher than in liver of fed normal animals, but only a small amount of the enzyme in the active form.
C, Watts, R S, Malthus
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Glycogen Synthase Kinase‐3 [PDF]
International Journal of Alzheimer’s Disease, 2011 Glycogen synthase kinase-3 (GSK3) is a ubiquitous and promiscuous kinase that has been studied extensively for over four decades. Initial reports beginning in the 1970s described its role in cellular metabolic pathways fundamental to glucose metabolism, but in more recent years the number of reports describing aberrant GSK3 activity in pathological ...
Crouch, P +4 more
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Regulation of Glycogen Synthase by Glucose and Glycogen [PDF]
Diabetes, 2003 We report here use of human myoblasts in culture to study the relationships between cellular glycogen concentrations and the activities of glycogen synthase (GS) and AMP-activated protein kinase (AMPK). Incubation of cells for 2 h in the absence of glucose led to a 25% decrease in glycogen content and a significant decrease in the fractional activity ...
Reza Halse +4 more
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Alternative splicing of the porcine glycogen synthase kinase 3β (GSK-3β) gene with differential expression patterns and regulatory functions. [PDF]
PLoS ONE, 2012 Glycogen synthase kinase 3 (GSK3α and GSK3β) are serine/threonine kinases involved in numerous cellular processes and diverse diseases including mood disorders, Alzheimer's disease, diabetes, and cancer.
Linjie Wang +7 more
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The role of glycogen phosphorylase in glycogen biogenesis in skeletal muscle after exercise
Sports Medicine and Health Science, 2023 Initially it was believed that phosphorylase was responsible for both glycogen breakdown and synthesis in the living cell. The discovery of glycogen synthase and McArdle's disease (lack of phosphorylase activity), together with the high Pi/glucose 1-P ...
Abram Katz
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Neural Regeneration Research, 2017 Myocardial ischemia/reperfusion injury can lead to severe brain injury. Glycogen synthase kinase 3 beta is known to be involved in myo-cardial ischemia/reperfusion injury and diabetes mellitus. However, the precise role of glycogen synthase kinase 3 beta
Bo Zhao +7 more
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Ambient pH controls glycogen levels by regulating glycogen synthase gene expression in Neurospora crassa. New insights into the pH signaling pathway. [PDF]
PLoS ONE, 2012 Glycogen is a polysaccharide widely distributed in microorganisms and animal cells and its metabolism is under intricate regulation. Its accumulation in a specific situation results from the balance between glycogen synthase and glycogen phosphorylase ...
Fernanda Barbosa Cupertino +3 more
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