Results 131 to 140 of about 46,712 (217)

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

Small, Volume 22, Issue 16, 17 March 2026.
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti, Marius F.W. Trollmann, Christina Wichmann, Thomas Gutsmann, Christian Eggeling, Rainer A. Böckmann   +5 more
wiley   +1 more source

A Pilot Study Using Microbial Glycolipid Signatures to Diagnose Nosocomial Ventriculitis. [PDF]

Rapid Commun Mass Spectrom
O'Keefe IP, Putnam N, Ernst RK, Doub JB.
europepmc   +1 more source

Mechanism elucidation of cell‐selective fluorescent probes

Smart Molecules, Volume 4, Issue 1, March 2026.
This perspective outlines five mechanistic strategies—Protein‐oriented, carbohydrate‐oriented, lipid‐oriented, gating‐oriented, and metabolism‐oriented live‐cell distinctions—for achieving cell‐selective fluorescence in live‐cell imaging. By classifying probes based on their interactions with proteins, carbohydrates, lipids, transporters, or metabolic ...
Sourav Sarkar, Young‐Tae Chang
wiley   +1 more source

Glucolipid metabolic disorders and ferroptosis in diabetic ulcers: pathogenic crossroads and therapeutic opportunities. [PDF]

Front Endocrinol (Lausanne)
Yeerbao Z, Li X, Zhang L, Du G, Tang J, Jiang S, Ru X, Li D, Abulimiti D, Chen L, Deng Y, Aihemaitijiang G, Halimulati H, Li Y, Tian Y.   +14 more
europepmc   +1 more source

Lipid Nanoparticles in Drug Delivery: Overcoming Challenges and Unlocking New Frontiers

Small Structures, Volume 7, Issue 3, March 2026.
Lipid nanoparticles (LNPs) have revolutionized nucleic acid delivery, yet challenges in formulation, stability, and targeted efficacy persist. This review explores how advances in microfluidic manufacturing, precision targeting, and endosomal escape are reshaping LNP design.
Jordan Kambanis, Lauren A. Lowe, Jingyi Yao, Zhenxu Yang, Shaoxue Zeng, Ken‐Tye Yong, Ling Zhu, Yi Shen   +7 more
wiley   +1 more source

Metabolic phenotyping of sepsis in large multicenter cohorts: identification of a reproducible high-risk subgroup. [PDF]

Lipids Health Dis
Zhang Y, Liu G, Shang Z, Yu X, Shang H, Cui X, Chen J, Ye J, Zhang J, Zhai Y, Qian J, Ma C, Liu W, Chen M, Zhao B, Gao C.   +15 more
europepmc   +1 more source

Trends in Dietary Exosome‐Like Nanoparticles: Preparation, Nutritional Functions, Bioactive Delivery Efficacy, Human Health Effects, and Future Product Development

Small Structures, Volume 7, Issue 3, March 2026.
This graphical abstract summarizes the current advances in dietary exosome‐like nanoparticles (ELNs), highlighting their biogenesis pathways (MVB‐dependent, vacuole‐mediated, and EXPO routes), molecular composition (nucleic acids, lipids, proteins, and bioactive compounds), and major preparation strategies including differential ultracentrifugation ...
Nidesha Randeni, Jinhai Luo, Min‐Hsiung Pan, Baojun Xu   +3 more
wiley   +1 more source

BDH1 Mediates Aerobic Exercise-Induced Improvement in Skeletal Muscle Metabolic Remodeling in Type 2 Diabetes Mellitus. [PDF]

Biomolecules
Wu M, Ma X, Dai W, Li K, Gao H, Guo Y, Xiao W.   +6 more
europepmc   +1 more source

Two‐Dimensional Frameworks From Metal Oxo Clusters at Liquid Interfaces

Small Structures, Volume 7, Issue 3, March 2026.
A two‐dimensional analog of the hexagonally close‐packed UiO‐66 metal–organic framework is assembled as a Langmuir monolayer at liquid interfaces using preformed metal oxo clusters and tailor‐made organic linkers. Coordination‐driven self‐assembly governs film formation, while linker amphiphilicity confines growth to two dimensions.
Ajmal Roshan Unniram Parambil, Muhammed Jibin Parammal, Prashant Hitaishi, Seyed Amirabbas Nazemi, Narmadha Devi Suresh Kumar, Alla Sologubenko, Stephan Handschin, Bridget M. Murphy, Thomas A. Jung, Jonathan De Roo, Patrick Shahgaldian   +10 more
wiley   +1 more source

Bifunctional glycolipids targeting TLR4·MD-2 and short pentraxins. [PDF]

RSC Chem Biol
Zucchetta D, Nuschy L, Gumpelmair S, Steinberger P, Wilson I, Heine H, Zamyatina A.   +6 more
europepmc   +1 more source