Results 151 to 160 of about 10,062 (222)
Donor‐induced conformational gating and substrate‐assisted catalysis in α‐1,3‐galactosyltransferase
Protein Science, Volume 35, Issue 9, September 2026.Abstract Retaining glycosyltransferases catalyze the formation of stereochemically conserved glycosidic bonds through mechanisms that remain debated. Using bovine α1,3‐galactosyltransferase (α3GalT) as a model, we combine mutagenesis, equilibrium unfolding, kinetics, and molecular dynamics simulations to understand how donor‐induced loop ordering ...
Javier A. Linares‐Pastén +1 more
wiley +1 more source
Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 9, Page 1610-1627, September 2026.ABSTRACT The role of the cell envelope‐associated Rv0132c/FGD2 from Mycobacterium tuberculosis has long been a subject of debate. Importantly, FGD2 is found only in pathogenic mycobacteria, making it a potential drug target. While some suggest it functions as a glucose‐6‐phosphate dehydrogenase, others propose it acts instead as an F420‐dependent ...
Adewale V. Aderemi +12 more
wiley +1 more source
Chemical approaches to the glycolipid biological mechanism of action
, 2010 F. Compostella +2 more
core +2 more sources
Akkermansia muciniphila and Its Bioactive Derivatives: Emerging Regulators of Healthy Aging
Aging Cell, Volume 25, Issue 9, September 2026.The beneficial gut bacterium Akkermansia muciniphila (AKK) declines with age but is enriched in healthy centenarians. Supplementation of AKK extends healthspan and alleviates age‐related decline through direct host–microbe interactions and its bioactive derivatives, which collectively enhance gut barrier integrity, restore metabolic homeostasis ...
Ting Zhang +7 more
wiley +1 more source
Some Exposure for Influenza Hemagglutinin Interface Antibodies
Immunological Reviews, Volume 342, Issue 1, September 2026.ABSTRACT Influenza viruses are a constant threat to human health. Current vaccines often confer low to moderate protection against infection with seasonal viruses and little‐to‐no protection against pandemic viruses. Improved vaccines are needed. These vaccines will need to reliably elicit antibodies to conserved sites that are broadly protective.
Kevin R. McCarthy
wiley +1 more source
Immunological Reviews, Volume 342, Issue 1, September 2026.ABSTRACT Human infection with or vaccination against influenza A virus has been one of the most informative systems for understanding how human antibody repertoires recognize viral glycoproteins. Decades of antibody isolation, repertoire sequencing, lineage tracing, serology, viral antigenic evolution, and structural biology have shown that antibody ...
Bruno Bonnettaz, Goran Bajic
wiley +1 more source
Molecular Microbiology, Volume 126, Issue 3, Page 237-243, September 2026.The glycosyltransferase All4160 is regulated by the reversible phosphorylation of Ser74. The kinase Alr3423 phosphorylates and inactivates All4160, while the SpoIIE‐like phosphatase HenR restores its activity through dephosphorylation. A nonphosphorylatable variant of All4160 bypasses the need for HenR, which demonstrates that a phosphorylation ...
Mai Harada +2 more
wiley +1 more source
New Phytologist, Volume 251, Issue 5, Page 2574-2587, September 2026.Grazing rates of Ochromonas CCMP2951 expressed as carbon obtained per mean cell volume (a) and Caut/het‐photosynthetically fixed carbon divided by carbon obtained through grazing (b) in the four experimental treatments. Summary Mixotrophic protists capable of both photosynthesis and phagotrophy are key members of marine plankton communities.
Shai Slomka +4 more
wiley +1 more source
Functional Specialization of Clathrin‐Independent Endocytic Routes: Mechanisms and Cellular Roles
Traffic, Volume 27, Issue 3, September 2026.Distinct clathrin‐independent endocytic (CIE) routes support specialized cellular functions across different contexts. Created with Biorender.com. ABSTRACT Clathrin‐independent endocytosis (CIE) comprises a diverse repertoire of internalization mechanisms that operate in parallel with clathrin‐mediated endocytosis.
Andrea Francesco Benvenuto +5 more
wiley +1 more source
Land Degradation &Development, Volume 37, Issue 14, Page 10053-10062, 30 August 2026.ABSTRACT Species in grasslands restored from former arable land have multiple obstacles when establishing. Understanding whether these limitations stem from soil chemical or microbial differences could help to create suitable environments for specific target and other species with similar requirements.
Epp Maria Lillipuu +3 more
wiley +1 more source