Unravelling the structural complexity of glycolipids with cryogenic infrared spectroscopy [PDF]
Nature Communications, 2021 Glycolipids are glycoconjugates with important biological functions, but techniques for their analysis are deficient. Here, the authors report the use of cryogenic gas-phase infrared spectroscopy to investigate isomerism in a set of immunologically ...
Carla Kirschbaum +13 more
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Glycosylation of Glycolipids in Cancer: Basis for Development of Novel Therapeutic Approaches [PDF]
Frontiers in Oncology, 2013 Altered networks of gene regulation underlie many pathologies, including cancer. There are several proteins in cancer cells that are turned either on or off, which dramatically alters the metabolism and the overall activity of the cell, with the complex ...
Jose Luis Daniotti +4 more
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Analytical Approaches to the Rapid Characterisation of Marine Glycolipids in Bioproduct Discovery [PDF]
Marine DrugsGlycolipids are structurally diverse amphiphilic molecules with potential as non-petrochemical-derived bioproducts, including surfactants, emulsifiers, and antioxidants. The different bioactivities associated with this range of glycolipid structures also
Sudarshan Dhakal +3 more
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Identification of two glycosyltransferases required for synthesis of membrane glycolipids in Clostridioides difficile [PDF]
mBioClostridioides difficile infections cause over 12,000 deaths and an estimated one billion dollars in healthcare costs annually in the United States.
Brianne R. Zbylicki +3 more
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Yeast-derived glycolipids disrupt Candida biofilm and inhibit expression of genes in cell adhesion [PDF]
Scientific ReportsCandida albicans is a leading fungal pathogen in humans, responsible for infections that span from mucosal surfaces to severe systemic diseases. This study aimed to investigate potential ability of yeast-derived glycolipids from Meyerozyma guilliermondii
Kwanrutai Watchaputi +6 more
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Click mediated synthesis of functionalized glycolipids with peptide-peptoid linkages [PDF]
Journal of the Serbian Chemical Society, 2023 The present work describes the synthesis of a new class of glycolipids with systematic variations in the linkage region, as well as in the aglycon part using Cu(I) catalyzed click reaction.
Singhamahapatra Anadi +5 more
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Glycolipids as a promising ingredient in food and pharmaceutical technologies
Новые технологии, 2023 The relevance of the analysis of scientific publications devoted to the study of the composition, properties, methods of preparation, areas of application, as well as the qualitative and quantitative identification of glycolipids is determined by the ...
E. O. Gerasimenko +3 more
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Immunological hyporesponsiveness in tuberculosis: The role of mycobacterial glycolipids
Frontiers in Immunology, 2022 Glycolipids constitute a major part of the cell envelope of Mycobacterium tuberculosis (Mtb). They are potent immunomodulatory molecules recognized by several immune receptors like pattern recognition receptors such as TLR2, DC-SIGN and Dectin-2 on ...
Margarida Correia-Neves +11 more
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Interplay of Trans- and Cis-Interactions of Glycolipids in Membrane Adhesion
Frontiers in Molecular Biosciences, 2021 Glycolipids mediate stable membrane adhesion of potential biological relevance. In this article, we investigate the trans- and cis-interactions of glycolipids in molecular dynamics simulations and relate these interactions to the glycolipid-induced ...
Batuhan Kav +7 more
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Pharmaceutics, 2022 Melanomas account for 80% of skin cancer deaths. Due to the strong relationship between melanomas and U.V. radiation, sunscreens have been recommended for use as a primary preventative measure.
Simms A. Adu +4 more
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