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Glycomics and angiogenesis: biological implications and therapeutical exploiting
, 2006 RUSNATI, Marco +2 more
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Shotgun glycomics: a microarray strategy for functional glycomics [PDF]
Nature Methods, 2010 Major challenges of glycomics are to characterize a glycome and identify functional glycans as ligands for glycan-binding proteins (GBPs). To address these issues we developed a general strategy termed shotgun glycomics. We focus on glycosphingolipids (GSLs), a class of glycoconjugates that is challenging to study, recognized by toxins, antibodies and ...
Jeanne M Rhea +2 more
exaly +3 more sources
Glycomics@ExPASy: Bridging the Gap
Molecular and Cellular Proteomics, 2018 Glycomics@ExPASy (https://www.expasy.org/glycomics) is the glycomics tab of ExPASy, the server of SIB Swiss Institute of Bioinformatics. It was created in 2016 to centralize web-based glycoinformatics resources developed within an international network ...
Julien Mariéthoz +2 more
exaly +2 more sources
The minimum information required for a glycomics experiment (MIRAGE) project: sample preparation guidelines for reliable reporting of glycomics datasets [PDF]
Glycobiology, 2016 The minimum information required for a glycomics experiment (MIRAGE) project was established in 2011 to provide guidelines to aid in data reporting from all types of experiments in glycomics research including mass spectrometry (MS), liquid ...
Miloš Novotny +2 more
exaly +2 more sources
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Current Opinion in Chemical Biology, 2007
The study of protein-carbohydrate interactions is one central theme of glycomics research. The challenges encountered when investigating these interactions have resulted in an approach that studies saccharides through the enzymes that process them. Proteins and their function are often probed by manipulating the genes that encode them.
Timmer, M., Stocker, B., Seeberger, P.
openaire +4 more sources
The study of protein-carbohydrate interactions is one central theme of glycomics research. The challenges encountered when investigating these interactions have resulted in an approach that studies saccharides through the enzymes that process them. Proteins and their function are often probed by manipulating the genes that encode them.
Timmer, M., Stocker, B., Seeberger, P.
openaire +4 more sources
Relative versus absolute quantitation in disease glycomics
Proteomics - Clinical Applications, 2015 The glycome of a diagnostic biological material such as blood, urine, saliva, tissue, or cell cultures comprises of a vast array of structurally distinct glycans attached to the protein complement. Aberrant glycan structures and distributions result from
Morten Andersen +2 more
exaly +2 more sources
Mass Spectrometry-Based N-Glycomics of Colorectal Cancer
International Journal of Molecular Sciences, 2015 Colorectal cancer (CRC) is one of the most prevalent cancers worldwide. An increased molecular understanding of the CRC pathology is warranted to gain insights into the underlying molecular and cellular mechanisms of the disease.
Manveen Sethi, Susan Fanayan
exaly +2 more sources
2009
Metabolomics is essentially the study of all low molecular weight molecules in a biological system under defined conditions. In glycomics, there is much potential to gain insight into the biosynthesis of novel glycoconjugate structures by probing the metabolome for substrates that are suspected, or known, to be involved in the biosynthetic processes ...
Soo, Evelyn C., Hui, Joseph P. M.
openaire +3 more sources
Metabolomics is essentially the study of all low molecular weight molecules in a biological system under defined conditions. In glycomics, there is much potential to gain insight into the biosynthesis of novel glycoconjugate structures by probing the metabolome for substrates that are suspected, or known, to be involved in the biosynthetic processes ...
Soo, Evelyn C., Hui, Joseph P. M.
openaire +3 more sources