Results 21 to 30 of about 26,625 (243)

Prediction of Intact N-Glycopeptide Retention Time Windows in Hydrophilic Interaction Liquid Chromatography

open access: yesMolecules, 2022
Analysis of protein glycosylation is challenging due to micro- and macro-heterogeneity of the attached glycans. Hydrophilic interaction liquid chromatography (HILIC) is a mode of choice for separation of intact glycopeptides, which are inadequately ...
Petr Kozlik   +4 more
doaj   +1 more source

Evaluating the Performance of 193 nm Ultraviolet Photodissociation for Tandem Mass Tag Labeled Peptides

open access: yesAnalytica, 2021
Despite the successful application of tandem mass tags (TMT) for peptide quantitation, missing reporter ions in higher energy collisional dissociation (HCD) spectra remains a challenge for consistent quantitation, especially for peptides with labile post-
Mowei Zhou   +5 more
doaj   +1 more source

Acquisition of Daptomycin Resistance by Enterococcus faecium Confers Collateral Sensitivity to Glycopeptides

open access: yesFrontiers in Microbiology, 2022
Daptomycin is a last-line antibiotic used in the treatment of multidrug-resistant Enterococcus faecium infections. Alarmingly, daptomycin-resistant E. faecium isolates have emerged.
Weiliang Zeng   +10 more
doaj   +1 more source

Daptomycin versus Glycopeptides for the Treatment of Enterococcus faecium Bacteraemia: A Cohort Study

open access: yesAntibiotics, 2021
Background: Ampicillin resistant and glycopeptide susceptible Enterococcus faecium bloodstream infection (GSEF-BSI) incidence has risen. However, the treatment of choice remains unknown.
Daniel Echeverría-Esnal   +5 more
doaj   +1 more source

Chemical Synthesis of Glycopeptides containing l‑Arabinosylated Hydroxyproline and Sulfated Tyrosine

open access: yes, 2023
Post-translationally modified peptides are important regulating molecules for living organisms. Here, we report the stereoselective total synthesis of β-1,2-linked l-arabinosylated Fmoc-protected hydroxyproline building blocks and their incorporation ...
Bauke Albada (1781323)   +5 more
core   +1 more source

Validation and Clinical Application of a New Liquid Chromatography Coupled to Mass Spectrometry (HPLC-MS) Method for Dalbavancin Quantification in Human Plasma

open access: yesSeparations, 2021
Dalbavancin (DBV) is an intravenous long-acting second-generation glycolipopeptide antibiotic with high efficacy and excellent tolerability, approved for use in the treatment of Gram-positive skin and skin structure infections (ABSSSI).
Valeria Avataneo   +13 more
doaj   +1 more source

Tissue Penetration of Antimicrobials in Intensive Care Unit Patients: A Systematic Review—Part I

open access: yesAntibiotics, 2022
The challenging severity of some infections, especially in critically ill patients, makes the diffusion of antimicrobial drugs within tissues one of the cornerstones of chemotherapy.
Stefano Finazzi   +7 more
doaj   +1 more source

‐Glycopeptides Found in Serum [PDF]

open access: yes, 2018
Purpose Experimental design There are no blood biomarkers to detect early-stage oral cavity squamous cell carcinoma (OSCC) prior to clinical signs. Most OSCC incidence is associated with significant morbidity and poor survival.
Tohmola, Tiialotta   +20 more
core   +1 more source

Determination of the safety of glycopeptides lactic acid bacteria in laboratory animals

open access: yesФармакокинетика и Фармакодинамика, 2019
The study of acute toxicity and allergenity glycopeptides lactic acid bacteria in mice and rabbits. At the present level of physical, chemical and biological pollution of the environment, domestic and farm animals in no less, if not more than people ...
O. V. Sofronova   +2 more
doaj   +1 more source

Cephalosporin-Glycopeptide Combinations for Use against Clinical Methicillin-Resistant Staphylococcus aureus Isolates: Enhanced In vitro Antibacterial Activity

open access: yesFrontiers in Microbiology, 2017
The empirical combination of both a beta-lactam and glycopeptide to counter potential staphylococcal pathogens may improve the clinical outcomes for cases of Staphylococcus aureus bacteremia.
Hung-Jen Tang   +13 more
doaj   +1 more source

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