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Why enveloped viruses need cores -- the contribution of a nucleocapsid core to viral budding [PDF]

open access: yes, 2017
During the alphavirus lifecycle, a nucleocapsid core buds through the cell membrane to acquire an outer envelope of lipid membrane and viral glycoproteins. However, the presence of a nucleocapsid core is not required for assembly of infectious particles.
Hagan, Michael F.   +2 more
arxiv   +3 more sources

Identification of Secreted O-Mannosylated Proteins From BCG and Characterization of Immunodominant Antigens BCG_0470 and BCG_0980

open access: yesFrontiers in Microbiology, 2020
Bacterial glycoproteins have been investigated as vaccine candidates as well as diagnostic biomarkers. However, they are poorly understood in Mycobacterium bovis strain bacille Calmette-Guérin (BCG), a non-pathogenic model of Mycobacterium tuberculosis ...
Guoying Deng   +6 more
doaj   +1 more source

Detection of Nipah and Hendra Viruses Using Recombinant Human Ephrin B2 Capture Virus in Immunoassays

open access: yesViruses, 2022
Nipah virus (NiV) and Hendra virus (HeV) are classified as high-consequence zoonotic viruses characterized by high pathogenicity and high mortality in animals and humans. Rapid diagnosis is essential to containing the outbreak.
Ming Yang   +6 more
doaj   +1 more source

Distant sequence similarity between hepcidin and the novel coronavirus spike glycoprotein: a potential hint at the possibility of local iron dysregulation in COVID-19 [PDF]

open access: yesBiol. Direct 15 (2020) 19, 2020
The spike glycoprotein of the SARS-CoV-2 virus, which causes COVID-19, has attracted attention for its vaccine potential and binding capacity to host cell surface receptors. Much of this research focus has centered on the ectodomain of the spike protein. The ectodomain is anchored to a transmembrane region, followed by a cytoplasmic tail.
arxiv   +1 more source

A Novel Class of Elicitin-like Genes from Phytophthora infestans

open access: yesMolecular Plant-Microbe Interactions, 1997
Elicitins are a family of structurally related proteins that induce hypersensitive response in specific plant species. Two Phytophthora infestans cDNAs, inf2A and inf2B, potentially encoding novel elicitin-like proteins, were isolated from a cDNA library
Sophien Kamoun   +2 more
doaj   +1 more source

The S-layer protein of the anammox bacterium Kuenenia stuttgartiensis is heavily O-glycosylated

open access: yesFrontiers in Microbiology, 2016
Anammox bacteria are a distinct group of Planctomycetes that are characterized by their unique ability to perform anaerobic ammonium oxidation with nitrite to dinitrogen gas in a specialized organelle.
Muriel C.F. van Teeseling   +8 more
doaj   +1 more source

Extraction of Auricularia auricula Glycoprotein and Analysis of Monosaccharide and Amino Acid Composition

open access: yesShipin gongye ke-ji, 2023
In order to obtain high-quality Auricularia auricula glycoprotein and clarify its monosaccharide and amino acid composition, the process conditions of ultrasonic assisted alkaline extraction of Auricularia auricula glycoprotein were optimized by single ...
Yingbin WANG   +3 more
doaj   +1 more source

Similarity Is Not Enough: Tipping Points of Ebola Zaire Mortalities [PDF]

open access: yes, 2014
In early 2014 an outbreak of a slightly mutated Zaire Ebola subtype appeared in West Africa which is less virulent than 1976 and 1994 strains. The numbers of cases per year appear to be ~ 1000 times larger than the earlier strains, suggesting a greatly enhanced transmissibility.
arxiv   +1 more source

Gulose as a constituent of a glycoprotein [PDF]

open access: yesFEBS Letters, 1992
The aldohexose gulose was identified as a constituent of a hydroxyproline‐rich glycopeptide derived from the glycoprotein SSG 185. This glycoprotein is part of the extracellular matrix of the green alga Volvox carteri. The gulose residue occupies a terminal position in the corresponding saccharide.
Mengele, R., Sumper, Manfred
openaire   +4 more sources

Evaluation of Diagnostic Performance of Three Indirect Enzyme-Linked Immunosorbent Assays for the Detection of IgG Antibodies to Ebola Virus in Human Sera

open access: yesViruses, 2019
Filovirus serological diagnosis and epidemiological investigations are hampered due to the unavailability of validated immunoassays. Diagnostic performance of three indirect enzyme-linked immunosorbent assays (I-ELISA) was evaluated for the detection of ...
Janusz T. Paweska   +6 more
doaj   +1 more source

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