Results 11 to 20 of about 998,690 (392)

SARS-CoV-2 Vaccines Based on the Spike Glycoprotein and Implications of New Viral Variants

open access: yesFrontiers in Immunology, 2021
Coronavirus 19 Disease (COVID-19) originating in the province of Wuhan, China in 2019, is caused by the severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), whose infection in humans causes mild or severe clinical manifestations that mainly
Daniel Martínez-Flores   +5 more
semanticscholar   +1 more source

Emerging COVID-19 coronavirus: glycan shield and structure prediction of spike glycoprotein and its interaction with human CD26

open access: yesEmerging Microbes and Infections, 2020
The recent outbreak of pneumonia-causing COVID-19 in China is an urgent global public health issue with an increase in mortality and morbidity. Here we report our modelled homo-trimer structure of COVID-19 spike glycoprotein in both closed (ligand-free ...
Naveen Vankadari, J. Wilce
semanticscholar   +1 more source

Characterisation of the transcriptome and proteome of SARS-CoV-2 reveals a cell passage induced in-frame deletion of the furin-like cleavage site from the spike glycoprotein

open access: yesGenome Medicine, 2020
SARS-CoV-2 is a recently emerged respiratory pathogen that has significantly impacted global human health. We wanted to rapidly characterise the transcriptomic, proteomic and phosphoproteomic landscape of this novel coronavirus to provide a fundamental ...
A. Davidson   +10 more
semanticscholar   +1 more source

The SARS-CoV-2 Spike Glycoprotein Biosynthesis, Structure, Function, and Antigenicity: Implications for the Design of Spike-Based Vaccine Immunogens

open access: yesFrontiers in Immunology, 2020
The ongoing pandemic of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), poses a grave threat to global public health and imposes a severe burden on the entire human society.
L. Duan   +5 more
semanticscholar   +1 more source

The surface glycoproteins of hantaviruses

open access: yesCurrent Opinion in Virology, 2021
Hantaviruses are rodent-borne viruses distributed worldwide, transmitted through the air and with the ability to spread from person to person. They maintain a non-symptomatic persistent infection in their rodent hosts, but their spillover to humans produces a renal or pulmonary syndrome associated with high fatality rates.
Guardado-Calvo, Pablo, Rey, Félix
openaire   +3 more sources

Production of glycoprotein-deleted rabies viruses for monosynaptic tracing and high-level gene expression in neurons

open access: yesNature Protocols, 2010
Recombinant rabies viruses rendered replication-deficient by the deletion of their envelope glycoprotein gene are useful tools for neuroscientists, permitting (1) extraordinarily high transgene expression levels within neurons, (2) retrograde infection ...
Citation Wickersham   +3 more
semanticscholar   +1 more source

Recent Developments in Deciphering the Biological Role of Plant Complex N-Glycans

open access: yesFrontiers in Plant Science, 2022
Asparagine (N)-linked protein glycosylation is a ubiquitous co- and posttranslational modification which has a huge impact on the biogenesis and function of proteins and consequently on the development, growth, and physiology of organisms.
Richard Strasser
doaj   +1 more source

Vesicular stomatitis virus glycoprotein is necessary for H-2-restricted lysis of infected cells by cytotoxic T lymphocytes [PDF]

open access: yes, 1978
Vesicular stomatitis virus (VSV) elicited cytotoxic thymus-derived lymphocytes (CTLs) in mice of the BALB/c and three congenic strains (BALB.b, BALB.k, BALB.HTG).
Baltimore, David   +3 more
core   +2 more sources

Synthesis, Antigenicity Against Human Sera and Structure-Activity Relationships of Carbohydrate Moieties from <em>Toxocara</em> larvae and Their Analogues

open access: yesMolecules, 2012
Stereocontrolled syntheses of biotin-labeled oligosaccharide portions containing the Galβ1-3GalNAc core of the TES-glycoprotein antigen obtained from larvae of the parasite <em>Toxocara</em> and their analogues have been accomplished ...
Takashi Tsuchiya   +5 more
doaj   +1 more source

Amino acid sequence elucidation of human acrosin-trypsin inhibitor (HUSI-II) reveals that Kazal-type proteinase inhibitors are structurally related to β-subunits of glycoprotein hormones [PDF]

open access: yes, 1990
The amino acid sequence of the acrosin-trypsin inhibitor HUSI-II from human seminal plasma is presented which unequivocally identifies HUSI-II as being of Kazal-type.
Eulitz, Manfred   +2 more
core   +1 more source

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