Results 241 to 250 of about 1,005,229 (334)

Fast-acting single-dose vesicular stomatitis virus-Sudan virus vaccine: a challenge study in macaques. [PDF]

Lancet Microbe
Fletcher P, O'Donnell KL, Feldmann F, Rhoderick JF, Clancy CS, Haase JA, Prator CA, Smith BJ, Gunn BM, Feldmann H, Marzi A.   +10 more
europepmc   +1 more source

Self-regulation of MGAT4A and MGAT4B activity toward glycoproteins through interaction of lectin domain with their own N-glycans

Naoko Osada, Sushil K. Mishra, Miyako Nakano, Yuko Tokoro, Masamichi Nagae, Robert J. Doerksen, Yasuhiko Kizuka   +6 more
openalex   +1 more source

Circadian control of P-glycoprotein in Hepa1-6 hepatocarcinoma tumor cells and Hepa1-6 tumor-bearing mice

, 2018
Narin Öztürk, Sandrine Dulong, Xiaomei Li, Françis Lévi, Alper Okyar   +4 more
openalex   +2 more sources

Activating the Osteoblastic USP26 Pathway Alleviates Multi‐Organ Fibrosis by Decreasing Insulin Resistance

Advanced Science, EarlyView.
The loss of Ubiquitin Specific Peptidase 26 (USP26) in osteoblasts results in decreased bone formation, as well as multi‐organ fibrosis associated with insulin resistance (IR). Mechanistically, the absence of USP26 reduces glycolysis and lactate accumulation, leading to decreased histone H3 lysine 18 lactylation (H3K18LA) in the promoter region of KH ...
Jiyuan Tang, Wenkai Ye, Liang He, Zhou Dan, Leilei Chang, Zijie You, Yuanyue Jiang, Guoqing Tang, Lianfu Deng, Changwei Li   +9 more
wiley   +1 more source

Glycoproteins

The Biochemical journal, 2010
Merry, T., Astrautsova, S.
openaire   +3 more sources

MRI characteristics during attack and remission distinguish patients with MOG antibody-associated disease from multiple sclerosis. [PDF]

J Neurol Neurosurg Psychiatry
Syc-Mazurek SB, Cacciaguerra L, Tajfirouz DA, Redenbaugh V, Krecke KN, Thakolwiboon S, Dinoto A, Madhavan A, Tillema JM, Lopez-Chiriboga AS, Valencia-Sanchez C, Sechi E, Chen JJ, Pittock SJ, Flanagan EP.   +14 more
europepmc   +1 more source

A Modular Vaccine Platform Against SARS‐CoV‐2 Based on Self‐Assembled Protein Nanoparticles

Advanced Science, EarlyView.
A modular BP26 nanoparticle vaccine platform incorporating the SpyTag/SpyCatcher system enables high‐density, repetitive antigen display with post‐expression flexibility. Conjugation of the SARS‐CoV‐2 RBD to BP26 nanoparticles elicits strong humoral immunity and confers protection against viral challenge in vivo.
Seojung Lee, Yejin Jang, Yujin Kim, Yumi Shin, Ji‐Joon Song, Meehyein Kim, Sangyong Jon   +6 more
wiley   +1 more source

Charting the Proteins of Oropouche Virus. [PDF]

Viruses
Thomas S.
europepmc   +1 more source

A Quantum Framework for Protein Binding‐Site Structure Prediction on Utility‐Level Quantum Processors

Advanced Science, EarlyView.
This study presents a hybrid quantum‐classical framework for accurate prediction of protein structures on utility‐level quantum processors. We evaluate the practical application of the Variational Quantum Eigen‐solver (VQE) in protein structure prediction and demonstrate its superiority over state‐of‐the‐art deep learning methods in molecular docking ...
Yuqi Zhang, Yuxin Yang, William Martin, Kingsten Lin, Zixu Wang, Cheng‐Chang Lu, Weiwen Jiang, Ruth Nussinov, Joseph Loscalzo, Qiang Guan, Feixiong Cheng   +10 more
wiley   +1 more source

DNA Nanostructure‐Templated Multivalency Enables Broad‐Spectrum Virus Inhibition

Advanced Science, EarlyView.
A honeycomb‐shaped DNA nanostructure is introduced that organizes nanobodies or aptamers into trimeric clusters mirroring the native hemagglutinin arrangement on influenza viruses. This geometry‐matched multivalency enhances binding avidity by up to 1000‐fold, resulting in robust, broad‐spectrum viral neutralization and a 30–55% improvement in host ...
Saurabh Umrao, Abhisek Dwivedy, Dhanush Gandavadi, Chi Chen, Lifeng Zhou, Jinwei Duan, Vineetha Mareddy, Ying Fang, Xing Wang   +8 more
wiley   +1 more source