Results 21 to 30 of about 998,690 (392)
Methods, 2005 Proteins following the secretory pathway acquire their proper tertiary and in certain cases also quaternary structures in the endoplasmic reticulum (ER). Incompletely folded species are retained in the ER and eventually degraded. One of the molecular mechanisms by which cells achieve this conformational sorting is based on monoglucosylated N-glycans ...
Trombetta, E. Sergio +1 more
openaire +3 more sources
Detection of Bourbon Virus-Specific Serum Neutralizing Antibodies in Human Serum in Missouri, USA
mSphere, 2022 Bourbon virus (BRBV) was first discovered in 2014 in a fatal human case. Since then it has been detected in the tick Amblyomma americanum in the states of Missouri and Kansas in the United States.
Gayan Bamunuarachchi +8 more
doaj +1 more source
PLoS Pathogens, 2018 The trimeric SARS coronavirus (SARS-CoV) surface spike (S) glycoprotein consisting of three S1-S2 heterodimers binds the cellular receptor angiotensin-converting enzyme 2 (ACE2) and mediates fusion of the viral and cellular membranes through a pre- to ...
Wenfei Song +3 more
semanticscholar +1 more source
P-Glycoprotein: One Mechanism, Many Tasks and the Consequences for Pharmacotherapy of Cancers
Frontiers in Oncology, 2020 P-glycoprotein or multidrug resistance protein (MDR1) is an adenosine triphosphate (ATP) binding cassette transporter (ABCB1) intensely investigated because it is an obstacle to successful pharmacotherapy of cancers.
A. Seelig
semanticscholar +1 more source
Fucosylation and protein glycosylation create functional receptors for cholera toxin
eLife, 2015 Cholera toxin (CT) enters and intoxicates host cells after binding cell surface receptors using its B subunit (CTB). The ganglioside (glycolipid) GM1 is thought to be the sole CT receptor; however, the mechanism by which CTB binding to GM1 mediates ...
Amberlyn M Wands +18 more
doaj +1 more source
Crystal Structure of the Pre-fusion Nipah Virus Fusion Glycoprotein Reveals a Novel Hexamer-of-Trimers Assembly. [PDF]
, 2015 Nipah virus (NiV) is a paramyxovirus that infects host cells through the coordinated efforts of two envelope glycoproteins. The G glycoprotein attaches to cell receptors, triggering the fusion (F) glycoprotein to execute membrane fusion.
Aguilar, Hector C +14 more
core +2 more sources
Proceedings of the National Academy of Sciences of the United States of America, 2000 To evaluate whether alterations in the multidrug-resistance (MDR)-1 gene correlate with intestinal MDR-1 expression and uptake of orally administered P-glycoprotein (PGP) substrates, we analyzed the MDR-1 sequence in 21 volunteers whose PGP expression ...
S. Hoffmeyer +10 more
semanticscholar +1 more source
Glycoprotein Processing and Glycoprotein Processing Inhibitors [PDF]
Plant Physiology, 1988 Considerable evidence is now accumulating from both in vivo and in vitro studies that the oligosaccharide chains of the plant N-linked glycoproteins undergo modification or processing reactions after the oligosaccharide has been transferred from its lipid-linked oligosaccharide intermediate to the protein.
openaire +3 more sources
Functional Divergence of Glycoprotein Hormone Receptors [PDF]
, 2010 Two lamprey glycroprotein hormone receptors (lGpH-R I and II) highly similar with gnathostome GpH-Rs were cloned from sea lamprey testes and thyroid, respectively.
Freamat, Mihael, Sower, Stacia A.
core +3 more sources
Vitronectin Levels in Leukocyte-platelet Rich Fibrin, Injectable-platelet Rich Fibrin, and Serum: A Cross-sectional Study [PDF]
Journal of Clinical and Diagnostic ResearchIntroduction: Platelet-rich Fibrin (PRF) is an autologous platelet concentrate preparation containing several proteins that aid in healing. Vitronectin is one of these proteins that has not been quantified in all types of PRF. Various protocols have been
Anirudh B Acharya +4 more
doaj +1 more source