Results 121 to 130 of about 43,195 (149)

The snake venom toxin alboaggregin-A activates glycoprotein VI

Blood, 2001
The glycoprotein (GP)–Ib-IX-V receptor complex has recently been reported to signal through a pathway similar to that used by the collagen receptor GPVI, with a critical role described for the Fc receptor γ-chain. The evidence for this was based in part on studies with the GPIbα-selective snake venom toxin, alboaggregin-A.
N, Asazuma, S J, Marshall, O, Berlanga, D, Snell, A W, Poole, M C, Berndt, R K, Andrews, S P, Watson   +7 more
openaire   +2 more sources

Platelet Glycoprotein VI Haplotypes and the Presentation of Paediatric Sepsis

Thrombosis and Haemostasis, 2018
AbstractSepsis triggers a complex series of pathophysiologic events involving inflammatory responses and coagulation abnormalities. While circulating blood platelets are well-characterized for their contributions to coagulation, increasingly platelet-dependent effects on inflammation are being recognized.
Ahmed, Asfari, Judith A, Dent, Adam, Corken, Danielle, Herington, Vamsikrishna, Kaliki, Natasha, Sra, Glenda, Hefley, Sanjiv, Pasala, Parthak, Prodhan, Jerry, Ware   +9 more
openaire   +2 more sources

Interaction of calmodulin with the cytoplasmic domain of platelet glycoprotein VI

Blood, 2002
The platelet collagen receptor, glycoprotein VI (GPVI), and GPIb-IX-V, which binds von Willebrand factor, initiate platelet aggregation at low or high shear stress, respectively. We recently reported that positively charged, membrane-proximal sequences within cytoplasmic domains of GPIbβ and GPV of GPIb-IX-V bind calmodulin.
Robert K, Andrews, Katsue, Suzuki-Inoue, Yang, Shen, David, Tulasne, Stephen P, Watson, Michael C, Berndt   +5 more
openaire   +2 more sources

Mechanical circulatory support is associated with loss of platelet receptors glycoprotein Ibα and glycoprotein VI

Journal of Thrombosis and Haemostasis, 2016
Essentials Relationship of acquired von Willebrand disease (VWD) and platelet dysfunction is explored. Patients with ventricular assist devices and on extracorporeal membrane oxygenation are investigated. Acquired VWD and platelet receptor shedding is demonstrated in the majority of patients.
P, Lukito, A, Wong, J, Jing, J F, Arthur, S F, Marasco, D A, Murphy, P J, Bergin, J A, Shaw, M, Collecutt, R K, Andrews, E E, Gardiner, A K, Davis   +11 more
openaire   +2 more sources

Platelet Receptor Glycoprotein VI in Ischaemic Stroke

2020
Platelet activation, thrombus growth and subsequent thromboembolism underpins the pathophysiology of ischaemic stroke. At sites of atherothrombotic plaque rupture, it is established that platelet surface receptor glycoprotein (GP) VI-dimer binds to exposed sub-endothelial collagen, initiating the signalling required to cause platelet activation.
openaire   +1 more source

Plasma Soluble Glycoprotein VI: A Biomarker of Bleeding

Thrombosis and Haemostasis, 2023
openaire   +2 more sources

Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein

Cell, 2020
Alexandra C Walls, Young-Jun Park, M Alejandra Tortorici   +2 more
exaly  

The Hantavirus Surface Glycoprotein Lattice and Its Fusion Control Mechanism

Cell, 2020
Alexandra Serris, Robert Stass, Eduardo A Bignon   +2 more
exaly  

Humanized Glycoprotein VI Mouse to Study Anti-Glycoprotein VI Agents In Vivo

The Journal of Pharmacology and Experimental Therapeutics, 2012
openaire   +1 more source

Ebola Virus Glycoprotein with Increased Infectivity Dominated the 2013–2016 Epidemic

Cell, 2016
William E Diehl, Aaron E Lin, Nathan D Grubaugh   +2 more
exaly