Results 131 to 140 of about 238,504 (307)

Evaluating the CRP Interactome: Insights into Possible Novel Roles in Cellular Signaling and Tumorigenicity

Current Issues in Molecular Biology
C-reactive protein (CRP) is a well-known acute phase reactant and putative biomarker for advancing and chronically established inflammation. Its biological activity across its multiple isoforms plays various roles in the initiation, potentiation, and ...
Alison Gerhardt, Dlen Nanakaliy, Harnish D. Shah, Syed Sarfaraz, Charlotte Madigan, Makenna Downing, Robert P. Elliott, Rafid Dipto, Bella Vrapciu, Joseph W. Noetzel, Jessica Armas, Ayesha Ahmed, Marc Potempa, Margaret E. Olson, Lawrence A. Potempa, Peter C. Hart   +15 more
doaj   +1 more source

Bio‐Inspired Oligocellulose‐Regulated Ice‐Water Interfaces Enable Sustained Ion Transport in Frozen Aqueous Zinc Batteries

Advanced Science, EarlyView.
Inspired by antifreeze glycoproteins (AFGPs), we synthesized a type of oligomeric cellulose (OC‐8) to inhibit ice formation and enlarge the inter‐ice water channel for transportation. Typical confocal fluorescence experiments display the expansion of the ice‐water interface for zinc‐ion transport.
Zeyu Zhu, Jingxuan Pan, Haoran Ma, Boya Yuan, Cristina Carucci, Sunghak Park, Chong Gao, Minmin Liang, Kaiqi Li, Wei Li, Dan Wang, Xiaoting Chen, Zhiyuan He   +12 more
wiley   +1 more source

Enzyme‐Linked Cycloaddition Assay (ELCA) for Rapid, Ultra‐Sensitive Monitoring of Secreted Sialoglycoproteins [PDF]

Advanced science
Secreted glycoproteins report on cellular state faster than the cell surface, yet remain hard to measure. The Enzyme‐Linked Cycloaddition Assay (ELCA) combines metabolic azide labeling with click chemistry in an ELISA‐like microplate format, resolving sialylation changes within minutes for 1‐2 EUR per sample.
Lundstrøm J, Yang J, Bojar D.
europepmc   +2 more sources

N‑Glycoproteomics of Human Seminal Plasma Glycoproteins

, 2016
Seminal plasma aids sperm by inhibiting premature capacitation, helping in the intracervical transport and formation of an oviductal sperm reservoir, all of which appear to be important in the fertilization process.
Sarman Singh (52206), Mayank Saraswat (124763), Sakari Joenväärä (1397176), Risto Renkonen (172507), Anil Kumar Tomar (124764), Savita Yadav (124767)   +5 more
core   +1 more source

Defect‐Engineered BiO2‐X Nanosheets Mediate Sono‐Thermomechanical ECM Remodeling for Hepatocellular Carcinoma Immunotherapy

Advanced Science, EarlyView.
Herein, an ultrasound‐responsive BiO2‐X/siFn1 nanoplatform is developed to overcome anti‐PD‐1 resistance in hepatocellular carcinoma. Upon ultrasound irradiation, the platform downregulates fibronectin expression, while its sonothermal effect softens the dense extracellular matrix and activates antitumor immunity in the tumor microenvironment, thereby ...
Huimin Tian, Shen Zhang, Bolin Wu, Yichi Chen, Haitao Shang, Haoyan Tan, Chunyue Wang, Weichen Xu, Huixiong Xu, Haohao Yin, Wen Cheng   +10 more
wiley   +1 more source

Intracellular trafficking of lysosomal membrane glycoproteins [PDF]

, 1996
P(論文)Lysosomes are single membrane-bounded vacuoles. A vast number of acid hydrolases in the lysosomal matrix degrades intracellular and extracellular macromolecules such as proteins, polysaccharides, and nucleic acids.
赤崎, 健司, 辻, 宏, 35562, 35561
core  

Design and Synthesis of Antifreeze Glycoproteins and Mimics

, 2010
New synthetic routes to antifreeze glycoproteins as pure glycoforms, the identification of cyclic antifreeze glycoproteins, structure-activity studies, conformational studies and the properties of novel C-linked analogues, present opportunities for the ...
Margaret M. Harding, Harding, Margaret, James Garner, Garner, James   +3 more
core   +1 more source

Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T‐Cell Immunity

Advanced Science, EarlyView.
Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang, Zijian Zhang, Fulin Dai, Zhijie Yin, Zhen Xing, Yurong Li, Haochong Lei, Junfeng Zhang, Chunyan Liu, Yan Li, Lei Dong   +10 more
wiley   +1 more source

cDNA cloning and characterization of rat salivary glycoproteins

, 1995
The cDNAs for two glycoproteins, the 158-kDa submandibular glycoprotein (SGP158) and the 200-kDa parotid glycoprotein (PGP200), have been cloned from rat submandibular and parotid glands, respectively.
Subramaniam, V. Nathan, Miao, Yong-Jie, Carlson, Don M.   +2 more
core   +1 more source

A Photothermally Amplified Enzyme–Nitric Oxide Co‐Regulatory System Reprograms Pathological ECM–Fibroblast Crosstalk to Alleviate Hypertrophic Scarring

Advanced Science, EarlyView.
An enzyme–nitric oxide (NO) co‐regulatory strategy reprograms pathological extracellular matrix (ECM)–fibroblast crosstalk in hypertrophic scars. Enzymatic degradation of pre‐existing ECM relieves aberrant mechanical cues, while NO‐mediated fibroblast phenotypic modulation restrains excessive collagen synthesis.
Junzhe Fu, Fan Jia, Yixian Mu, Wanzhe Liu, Dingqi Tang, Qiao Jin, Jian Ji, Youxiang Wang   +7 more
wiley   +1 more source