Results 111 to 120 of about 210,654 (311)

Engineering synthetic glycoproteins [PDF]

, 2020
Post-translational glycosylation of proteins is an extremely complex process, involving large enzymatic cascades leading to many heterogeneous glycoforms. Performing glycosylation using chemical, or chemoenzymatic processes to mimic natural glycoproteins
McBerney, Ryan Carl
core  

Identification of O-Linked Glycoproteins Binding to the Lectin Helix pomatia Agglutinin as Markers of Metastatic Colorectal Cancer. [PDF]

, 2015
BACKGROUND: Protein glycosylation is an important post-translational modification shown to be altered in all tumour types studied to date. Mucin glycoproteins have been established as important carriers of O-linked glycans but other glycoproteins ...
Fry, S, Loizidou Marilena, Peiris, D, Fry, S., Dwek, MV, Marilena Loizidou (817610), Smith-Ravin Juliette, Smith-Ravin, J, Marlène Ossondo (817609), Loizidou, M., Smith-Ravin, J., Simon Fry, Miriam V. Dwek (817612), Loizidou, M, Dwek, M., Diluka Peiris, Ossondo Marlène, Dwek Miriam V., Ossondo, M, Peiris, D., Juliette Smith-Ravin, Fry Simon, Simon Fry (5665618), Marlène Ossondo, Marilena Loizidou, Miriam V Dwek, Peiris Diluka, Diluka Peiris (817608), Ossondo, M., Juliette Smith-Ravin (817611)   +29 more
core   +1 more source

Brain sweet brain: importance of sugars for the cerebral microenvironment and tumor development Cérebro doce cérebro: importância dos açúcares para o microambiente cerebral e o desenvolvimento tumoral

Arquivos de Neuro-Psiquiatria, 2010
The extracellular matrix (ECM) in the brain tissue is a complex network of glycoproteins and proteoglycans that fills the intercellular space serving as scaffolding to provide structural framework for the tissue and regulate the behavior of cells via ...
Thereza Quirico-Santos, Clovis O Fonseca, Jussara Lagrota-Candido   +2 more
doaj   +1 more source

Chamber‐Specific Decellularized Extracellular Matrices Differentially Modulate Cardiomyocyte Subtypes to Drive Engineered Heart Tissue Development and Function

Advanced Healthcare Materials, EarlyView.
Chamber‐specific decellularized extracellular matrices (ECMs) were developed, preserving native proteomic profiles of ventricular and atrial myocardium. These innate biochemical cues differentially modulate cardiomyocyte subtypes to drive engineered heart tissue development and function, highlighting the importance of incorporating regional ECM cues in
Dong Gyu Hwang, Myungji Kim, Hwanyong Choi, Jinseon Park, Minji Kim, Donghwan Kim, Bo Ram Lee, Jinah Jang   +7 more
wiley   +1 more source

Development of a vesicular stomatitis virus pseudotyped with herpes B virus glycoproteins and its application in a neutralizing antibody detection assay

mBio
Herpes B virus (BV) is a zoonotic virus and belongs to the genus Simplexvius, the same genus as human herpes simplex virus (HSV). BV typically establishes asymptomatic infection in its natural hosts, macaque monkeys.
Hitomi Kinoshita, Souichi Yamada, Takuma Ogawa, Phu Hoang Anh Nguyen, Shizuko Harada, Madoka Kawahara, Keita Ishijima, Ken Maeda, Hideki Ebihara, Shuetsu Fukushi   +9 more
doaj   +1 more source

One‐Step Microfluidic Manufactured Fucose‐Decorated Sweetosomes Choose the Time and the Road for Their Intracellular Journey to Cancer Treatment

Advanced Healthcare Materials, EarlyView.
Sweetosomes, a new class of fucose‐decorated liposomes, are developed via a one‐step microfluidic process without surface chemistry. This study elucidates their main caveolae‐mediated entry and distinct endosomal trafficking. These nanostructures demonstrate superior endosomal escape, organelle acidity modulation, and prolonged plasma persistence ...
Mattia Tiboni, Mariele Montanari, Shiva Khorshid, Michele Verboni, Andrea Duranti, Simone Lucarini, Daniele Lopez, Annalisa Aluigi, Gianluca Morganti, Michele Menotta, Giovanna Panza, Daniel J. Klionsky, Barbara Canonico, Luca Casettari   +13 more
wiley   +1 more source

Increased infectivity of human cytomegalovirus strain TB40/E conferred by variants of the envelope glycoprotein UL128 and the regulatory protein IE2

Journal of Virology
Human cytomegalovirus (HCMV) infects various cell types in its human host, and this broad tropism plays a vital role in viral transmission, dissemination, and pathogenesis.
Xuan Zhou, Linjiang Yang, Giorgia Cimato, Giada Frascaroli, Ana Águeda-Pinto, Laura Hertel, Wolfram Brune   +6 more
doaj   +1 more source

Natural Biomaterials for Osteochondral Repair: From Source to Strategy

Advanced Healthcare Materials, EarlyView.
Biological origin‐guided overview of natural biomaterials and therapeutic strategies for osteochondral tissue engineering. The circular diagram categorizes representative materials and strategies into plant/algae‐derived, microbial‐derived, animal‐derived, and human‐derived sources, centered on an osteochondral defect repair model.
Hengyu Liu, Hanyang Zhang, Wenbo Yang, Hao Chen, Jincheng Wang, Fei Chang   +5 more
wiley   +1 more source

Equine Herpesvirus Infections: Treatment Progress and Challenges in Horses and Donkeys

Veterinary Sciences
Equine herpesvirus (EHV) infections represent a significant global veterinary and economic challenge affecting both horses and donkeys across all inhabited continents.
Muhammad Zahoor Khan, Yanfei Ji, Xuewei Fan, Yihong Liu, Wenqiang Liu, Changfa Wang   +5 more
doaj   +1 more source

Engineered AuNPs/fMWCNT Nanocomposite Electrodes for High‐Sensitivity Methylglyoxal Sensing in Saliva and Sweat for Non‐Invasive Diabetes Monitoring

Advanced Healthcare Materials, EarlyView.
An AuNPs/fMWCNT nanocomposite‐modified screen‐printed carbon electrode was engineered via sequential electrodeposition and integrated into a 3D‐printed microfluidic platform for ultrasensitive methylglyoxal detection. The non‐invasive sensing platform enables rapid analysis in saliva and sweat, highlighting strong potential for wearable point‐of‐care ...
Ahadul Amin Soshi, Md Younus Ali, Dadbeh Pazuki, Matiar M.R. Howlader   +3 more
wiley   +1 more source