Results 221 to 230 of about 238,504 (307)

Immobilised enzyme reactors for post-production glycan modification of purified glycoproteins. [PDF]

Front Mol Biosci
DeBono NJ, Cain J, Lin CH, Packer NH, Moh ESX.   +4 more
europepmc   +1 more source

Circulating Exosomes Drive Persistent Neuronal Dysfunction in Post‐Herpetic Neuralgia Patients

Annals of Neurology, EarlyView.
Proposed model of exosome‐mediated neuronal dysfunction in post‐herpetic neuralgia (PHN). (1) Circulating, non‐pathogenic exosomes maintain homeostatic processes in healthy skin, where sensory nerve fibers innervate the epidermis and dermis. (2) During acute zoster, reactivating varicella zoster virus (VZV) travels down neurites to the skin causing ...
Christy S. Niemeyer, Seth Frietze, Serena W.R. Lewis, Emily C. Artman, Christina Coughlan, Safa I. Vaseemuddin, Arianna Gentile Polese, Maria A. Nagel, Stephen K. Tyring, Fyona Okundia, Anthony J. Saviola, Gary C. Curhan, Sharon G. Curhan, Diego Restrepo, Andrew N. Bubak   +14 more
wiley   +1 more source

α2-3-Sialylated Glycoproteins Attenuate <i>Streptococcus mutans</i> Virulence and Associated Host Inflammatory Responses. [PDF]

Int J Mol Sci
Ren X, Wei L, Liu T, Wang M, Chang Z, Shu J, Li Z.   +6 more
europepmc   +1 more source

Serum Chitotriosidase Links to Activated Glia at Chronic Active Lesion Rims in Multiple Sclerosis Brain

Annals of Neurology, EarlyView.
Objective The objective of this study was to explore the association between 18 kDa translocator protein (TSPO)‐positron emission tomography (PET)–measurable glial activation and serum chitotriosidase (CHIT1) in people with multiple sclerosis (pwMS), and its expression in postmortem MS brain tissue.
Venla Ahola, Maija Saraste, Edoardo Pedrini, Joel Tuomaala, Luzia Buchholz, Markus Matilainen, Johanna Lindenberg, Eeva‐Christine Brockmann, Maria Sofia Martire, Sofia Sandgren, David Leppert, Jens Kuhle, Tanja Kuhlmann, Martina Absinta, Laura Airas   +14 more
wiley   +1 more source

Regio-specific glycan expression within the mammalian brain and tumors. [PDF]

iScience
Tulin EKC, Noel M, Pepi LE, Florido MH, Muerner L, Cielen L, von Gunten S, Cummings RD.   +7 more
europepmc   +1 more source

Astrocyte SMN Restoration and Forskolin Treatment Improve SMA Synaptic Pathology

Annals of Neurology, EarlyView.
Objective Early phenotypic presentation of central afferent synapse dysfunction within patients with spinal muscular atrophy (SMA) represents a key target for therapeutic development; however, the underlying disease mechanisms remain unresolved. By further investigating motor neuron synapse and peri‐synaptic astrocyte process (PAP) defects in human SMA
Emily Welby, Xiaojie Liu, Melinda Wojtkiewicz, Linda Berg Luecke, Rebekah L. Gundry, Qing‐Song Liu, Allison D. Ebert   +6 more
wiley   +1 more source

Optimized Simultaneous N/O-Glycopeptide Enrichment Strategy Identifies Lung Cancer Diagnostic Biomarkers in Serum. [PDF]

J Proteome Res
Zhou Z, Zhao J, Zhang J, Wu P, Yang Y, Li W, Peng C, Qiang Z.   +7 more
europepmc   +1 more source

Carbohydrate‐Directed Labeling Probes for UV‐Independent Chemoproteomic Profiling of Carbohydrate–Protein Interactions

Angewandte Chemie International Edition, Volume 65, Issue 44, 26 October 2026.
Modular carbohydrate‐directed labeling probes (CDLPs) convert weak carbohydrate–protein interactions into durable covalent tags in live cells without the need for multivalency or UV irradiation. Ligand binding triggers proximity‐enabled, glycan‐releasing acyl transfer to install a click handle for protein tagging and chemoproteomic profiling.
Matthew C. Russolillo, Wariya Nirachonkul, Nora Ross, Rahul M. Hedau, Zachary Clark, Michaella J. Rekowski, Michael P. Washburn, Mark P. Farrell   +7 more
wiley   +1 more source

Modulation of Leptin and Serotonin by Honey and Its Glycoproteins Against High-Fat Diet-Induced Metabolic and Anxiety Phenotypes. [PDF]

Biomedicines
Gohar A, Atkinson RL, Shakeel M, Haleem DJ, Ullah K, Rasool A.   +5 more
europepmc   +1 more source

Influence of Direct Saponification Conditions on Sterol Yield and Composition of the Unsaponifiable Fraction of the Microalga Isochrysis galbana and the Seaweed Ascophyllum nodosum

Journal of the American Oil Chemists' Society, EarlyView.
ABSTRACT Saponification is a key step for recovering the unsaponifiable fraction (USF) of lipids, which contains bioactive sterols, tocopherols, and carotenoids. This study optimized direct saponification conditions (50–300 g L−1 KOH; 60°C–100°C) to recover sterol‐rich USFs from the microalga Isochrysis galbana and the brown seaweed Ascophyllum nodosum,
Mina Zareie, Suzanne M. Budge
wiley   +1 more source