Viral glycoproteins: biological role and application in diagnosis
VirusDisease, 2016 The viruses that infect humans cause a huge global disease burden and produce immense challenge towards healthcare system. Glycoproteins are one of the major components of human pathogenic viruses. They have been demonstrated to have important role(s) in
Nilotpal Banerjee, S. Mukhopadhyay
semanticscholar +1 more source
Computational Modeling of Hepatitis C Virus Envelope Glycoprotein Structure and Recognition
Frontiers in Immunology, 2018 Hepatitis C virus (HCV) is a major global health concern, and though therapeutic options have improved, no vaccine is available despite decades of research.
Johnathan D. Guest +3 more
doaj +1 more source
Assembly of the Inner Perivitelline Layer, a Homo log of the Mammalian Zona Pellucida: An Immunohistochemical and Ultrastructural Study [PDF]
, 2012 The avian inner perivitelline layer (IPVL), a homologous structure to the mammalian zona pellucida, is deposited between the granulosa cells and the oocyte cell membrane during folliculogenesis. The glycoprotein meshwork of the IPVL forms a 3-dimensional
Bausek N. +37 more
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Incorporation of Spike and Membrane Glycoproteins into Coronavirus Virions
Viruses, 2015 The envelopes of coronaviruses (CoVs) contain primarily three proteins; the two major glycoproteins spike (S) and membrane (M), and envelope (E), a non-glycosylated protein.
M. Ujike, F. Taguchi
semanticscholar +1 more source
Glycan analysis of therapeutic glycoproteins
mAbs, 2015 Therapeutic monoclonal antibodies (mAbs) are glycoproteins produced by living cell systems. The glycan moieties attached to the proteins can directly affect protein stability, bioactivity, and immunogenicity.
Lei Zhang, Shen Luo, Baolin Zhang
semanticscholar +1 more source
Super-resolution microscopy reveals specific recruitment of HIV-1 envelope proteins to viral assembly sites dependent on the envelope C-terminal tail [PDF]
, 2013 The inner structural Gag proteins and the envelope (Env) glycoproteins of human immunodeficiency virus (HIV-1) traffic independently to the plasma membrane, where they assemble the nascent virion. HIV-1 carries a relatively low number of glycoproteins in
Heilemann, Mike +4 more
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Arquivos de Neuro-Psiquiatria, 2010 The extracellular matrix (ECM) in the brain tissue is a complex network of glycoproteins and proteoglycans that fills the intercellular space serving as scaffolding to provide structural framework for the tissue and regulate the behavior of cells via ...
Thereza Quirico-Santos +2 more
doaj +1 more source
Methods, 2005 Proteins following the secretory pathway acquire their proper tertiary and in certain cases also quaternary structures in the endoplasmic reticulum (ER). Incompletely folded species are retained in the ER and eventually degraded. One of the molecular mechanisms by which cells achieve this conformational sorting is based on monoglucosylated N-glycans ...
Trombetta, E. Sergio +1 more
openaire +3 more sources
Recombinant Flag-tagged E1E2 glycoproteins from three hepatitis C virus genotypes are biologically functional and elicit cross-reactive neutralizing antibodies in mice [PDF]
, 2018 Hepatitis C virus (HCV) is a globally disseminated human pathogen for which no vaccine is currently available. HCV is highly diverse genetically and can be classified into 7 genotypes and multiple sub-types. Due to this antigenic variation, the induction
Bieńkowska-Szewczyk, Krystyna +5 more
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Effects of Eimeria tenella infection on the barrier damage and microbiota diversity of chicken cecum
Poultry Science, 2020 The symbiosis of host and intestinal microbiota constitutes a microecosystem and plays an important role in maintaining intestinal homeostasis and regulating the host's immune system.
Bian-hua Zhou +5 more
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