Tomato spotted wilt virus glycoproteins induce the formation of endoplasmic reticulum- and Golgi-derived pleomorphic membrane structures in plant cells [PDF]
Tomato spotted wilt virus (TSWV) particles are spherical and enveloped, an uncommon feature among plant infecting viruses. Previous studies have shown that virus particle formation involves the enwrapment of ribonucleoproteins with viral glycoprotein ...
Kormelink, R.J.M. +5 more
core +1 more source
Chagas disease is caused by the hemoflagellate protozoan Trypanosoma cruzi. The main transmission mechanism for the parasite in endemic areas is contact with the feces of an infected triatomine bug. Part of the life cycle of T.
Olivia A. Reynoso-Ducoing +8 more
doaj +1 more source
Glycoprotein Processing and Glycoprotein Processing Inhibitors [PDF]
Considerable evidence is now accumulating from both in vivo and in vitro studies that the oligosaccharide chains of the plant N-linked glycoproteins undergo modification or processing reactions after the oligosaccharide has been transferred from its lipid-linked oligosaccharide intermediate to the protein.
openaire +2 more sources
Isolation and characterization of calcium binding glycoproteins of cardiac sarcolemmal vesicles [PDF]
Two major Ca2(+)-binding glycoproteins Mr 120,000 and 100,000 were isolated from 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonic acid -solubilized bovine heart sarcolemma membrane.
Michalak, M. +2 more
core +1 more source
Repurposed Single Inhibitor for Serine Protease and Spike Glycoproteins of SAR-CoV-2 [PDF]
In this research, structure of SARS-CoV-2 spike glycoprotein S1 and S2 along with TMPRSS2, TMPRSS4, TMPRSS11A, TMPRSS11D and TMPRSS11E serine protease (which activates S1 and S2) are used for docking with repurposed inhibitor drug molecules.
Mohtasheemul, Hassan +4 more
core +1 more source
Misexpression and remodeling of the extracellular matrix is a canonical hallmark of cancer, although the extent of cancer‐associated aberrations in the genes coding for extracellular matrix (ECM) proteins and the consequences thereof are not well ...
Jimpi Langthasa +4 more
doaj +1 more source
Pancreatic cancer (PC) remains one of the top 10 causes of cancer-related death in recent years. Approximately 80% of PC patients are diagnosed at the middle or advanced stage and miss the opportunity for surgery.
Shanshan Sha +6 more
doaj +1 more source
Glycoproteomic Analysis of Wga-Bound Glycoprotein Biomarkers in Sera from Patients with Lung Adenocarcinoma [PDF]
Differential protein expression profiles in the serum samples from patients with lung adenocarcinoma may be associated with glycosylation during cancer development.
HUANG-LIU, ROSA;PAN, FU-MING;CHUANG, YU-MIN;YU, CHONG-JEN;CHEN, SHUI-TEIN +1 more
core +1 more source
Construction and Evaluation of Recombinant Adenovirus Candidate Vaccines for Chikungunya Virus
Chikungunya virus (CHIKV) is a mosquito-borne virus. The emergence of CHIKV infection has raised global concern, and there is a growing need to develop safe and effective vaccines.
Liang Cao +10 more
doaj +1 more source
Mechanisms of productive folding and endoplasmic reticulum-associated degradation of glycoproteins and non-glycoproteins [PDF]
BACKGROUND: The quality of proteins destined for the secretory pathway is ensured by two distinct mechanisms in the endoplasmic reticulum (ER): productive folding of newly synthesized proteins, which is assisted by ER-localized molecular chaperones and ...
George, Ginto +2 more
core +3 more sources

