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Construction and Evaluation of Recombinant Adenovirus Candidate Vaccines for Chikungunya Virus
Viruses, 2022 Chikungunya virus (CHIKV) is a mosquito-borne virus. The emergence of CHIKV infection has raised global concern, and there is a growing need to develop safe and effective vaccines.
Liang Cao +10 more
doaj +1 more source
Mechanisms of productive folding and endoplasmic reticulum-associated degradation of glycoproteins and non-glycoproteins [PDF]
, 2021 BACKGROUND: The quality of proteins destined for the secretory pathway is ensured by two distinct mechanisms in the endoplasmic reticulum (ER): productive folding of newly synthesized proteins, which is assisted by ER-localized molecular chaperones and ...
George, Ginto +2 more
core +2 more sources
Microbiology Spectrum, 2022 Corals owe their ecological success to their symbiotic relationship with dinoflagellate algae (family Symbiodiniaceae). While the negative effects of heat stress on this symbiosis are well studied, how heat stress affects the onset of symbiosis and ...
Shumpei Maruyama +8 more
doaj +1 more source
The s-layer glycome-adding to the sugar coat of bacteria [PDF]
, 2011 This work was supported by the Austrian Science Fund FWF, projects P19047-B12, P20605-B12, P21954-B20 (to C. Sch¨affer), and P20745-B11 (to P. Messner). Zarschler and Ristl were supported by the Hochschuljubil¨aumsstiftung der Stadt Wien, Projects H-2229-
Zayni, Sonja +11 more
core +1 more source
Frontiers in Pharmacology, 2021 Background and Aims:Rabdosia japonica var. glaucocalyx is a traditional Chinese medicine (TCM) for various inflammatory diseases. This present work aimed to investigate the protective effects of R. japonica var.
An-qi Ren +7 more
doaj +1 more source
Methods, 2005 Proteins following the secretory pathway acquire their proper tertiary and in certain cases also quaternary structures in the endoplasmic reticulum (ER). Incompletely folded species are retained in the ER and eventually degraded. One of the molecular mechanisms by which cells achieve this conformational sorting is based on monoglucosylated N-glycans ...
Trombetta, E. Sergio +1 more
openaire +3 more sources
Identification of a Novel α-herpesvirus Associated with Ulcerative Stomatitis in Donkeys
Emerging Infectious Diseases, 2020 An outbreak of ulcerative stomatitis was observed in a donkey (Equus asinus) dairy herd. Similar lesions were also observed on the dams’ udders and, sporadically, in genital areas. The lesions typically resolved in 1–3 weeks.
Vito Martella +8 more
doaj +1 more source
Frontiers in Immunology, 2022 Rift Valley fever virus (RVFV) is one of the most important virulent pathogens causing severe disease in animals and humans. However, there is currently no approved vaccine to prevent RVFV infection in humans. The use of human adenovirus serotype 4 (Ad4)
Ting Bian +10 more
doaj +1 more source
Well Put Together—A Guide to Accessorizing with the Herpesvirus gH/gL Complexes
Viruses, 2022 Herpesviruses are enveloped, double-stranded DNA viruses that infect a variety of hosts across the animal kingdom. Nine of these establish lifelong infections in humans, for which there are no cures and few vaccine or treatment options.
Gonzalo L. Gonzalez-Del Pino +1 more
doaj +1 more source
mSphere, 2020 While Epstein-Barr virus (EBV) is the major cause of nasopharyngeal carcinoma (NPC), the value of the humoral immune response to EBV glycoproteins and NPC development remains unclear.
Qian-Ying Zhu +6 more
doaj +1 more source