Results 31 to 40 of about 238,504 (307)

Well Put Together—A Guide to Accessorizing with the Herpesvirus gH/gL Complexes

Viruses, 2022
Herpesviruses are enveloped, double-stranded DNA viruses that infect a variety of hosts across the animal kingdom. Nine of these establish lifelong infections in humans, for which there are no cures and few vaccine or treatment options.
Gonzalo L. Gonzalez-Del Pino, Ekaterina E. Heldwein   +1 more
doaj   +1 more source

Protein glycosylation in the gram-negative gamma proteobacterium photorhabdus luminescens [PDF]

, 2011
The objective of this research was to investigate the possibility that Photorhabdus luminescens produces glycoproteins and thus contains a protein glycosylation system. P. luminescens is a pathogen of insects and a symbiont of soil nematodes.
Fox, Mary
core   +2 more sources

Association between Antibody Responses to Epstein-Barr Virus Glycoproteins, Neutralization of Infectivity, and the Risk of Nasopharyngeal Carcinoma

mSphere, 2020
While Epstein-Barr virus (EBV) is the major cause of nasopharyngeal carcinoma (NPC), the value of the humoral immune response to EBV glycoproteins and NPC development remains unclear.
Qian-Ying Zhu, Xiang-Wei Kong, Cong Sun, Shang-Hang Xie, Allan Hildesheim, Su-Mei Cao, Mu-Sheng Zeng   +6 more
doaj   +1 more source

Similarities and Differences of Blood N-Glycoproteins in Five Solid Carcinomas at Localized Clinical Stage Analyzed by SWATH-MS

Cell Reports, 2018
Cancer is mostly incurable when diagnosed at a metastatic stage, making its early detection via blood proteins of immense clinical interest. Proteomic changes in tumor tissue may lead to changes detectable in the protein composition of circulating blood ...
Tatjana Sajic, Yansheng Liu, Eirini Arvaniti, Silvia Surinova, Evan G. Williams, Ralph Schiess, Ruth Hüttenhain, Atul Sethi, Sheng Pan, Teresa A. Brentnall, Ru Chen, Peter Blattmann, Betty Friedrich, Emma Niméus, Susanne Malander, Aurelius Omlin, Silke Gillessen, Manfred Claassen, Ruedi Aebersold   +18 more
doaj   +1 more source

Niemann-Pick type C1 protein regulates epidermal growth factor receptor stability in hepatic cells and facilitates the early steps of Hepatitis B virus infection

Frontiers in Cellular and Infection Microbiology
BackgroundChronic Hepatitis B virus (HBV) infection affects more than 250 million individuals worldwide, causing up to 1 million deaths yearly. Despite the significant disease burden, no curative therapy against HBV is currently available.
Stefania Ariadna Stefan-Buzatoiu, Petruta-Ramona Alexandru Flintoaca, Mihaela-Olivia Dobrica, Stefana-Maria Petrescu, Norica Branza-Nichita   +4 more
doaj   +1 more source

Genetic Diversity Underlying the Envelope Glycoproteins of Hepatitis C Virus: Structural and Functional Consequences and the Implications for Vaccine Design

Viruses, 2015
In the 26 years since the discovery of Hepatitis C virus (HCV) a major global research effort has illuminated many aspects of the viral life cycle, facilitating the development of targeted antivirals.
Alexander W. Tarr, Tanvi Khera, Kathrin Hueging, Julie Sheldon, Eike Steinmann, Thomas Pietschmann, Richard J. P. Brown   +6 more
doaj   +1 more source

TbGT8 is a bifunctional glycosyltransferase that elaborates N-linked glycans on a protein phosphatase AcP115 and a GPI-anchor modifying glycan in Trypanosoma brucei [PDF]

, 2014
The procyclic form of Trypanosoma brucei expresses procyclin surface glycoproteins with unusual glycosylphosphatidylinositol-anchor side chain structures that contain branched N-acetyllactosamine and lacto-N-biose units.
Hashida, Kazunori, Nakanishi, Masayuki, Karasudani, Moe, Nomoto, Hiroshi, Hino, Mami, Ferguson, Michael A. J; id_orcid, Shiraishi, Takahiro   +6 more
core   +1 more source

Potential Plasticity of the Mannoprotein Repertoire Associated to Mycobacterium tuberculosis Virulence Unveiled by Mass Spectrometry-Based Glycoproteomics

Molecules, 2020
To date, Mycobacterium tuberculosis (Mtb) remains the world’s greatest infectious killer. The rise of multidrug-resistant strains stresses the need to identify new therapeutic targets to fight the epidemic.
Laure Tonini, Bashir Sadet, Alexandre Stella, David Bouyssié, Jérôme Nigou, Odile Burlet-Schiltz, Michel Rivière   +6 more
doaj   +1 more source

Glycoprotein reglucosylation

Methods, 2005
Proteins following the secretory pathway acquire their proper tertiary and in certain cases also quaternary structures in the endoplasmic reticulum (ER). Incompletely folded species are retained in the ER and eventually degraded. One of the molecular mechanisms by which cells achieve this conformational sorting is based on monoglucosylated N-glycans ...
Trombetta, E. Sergio, Parodi, Armando José A.   +1 more
openaire   +3 more sources

ABH SECRETOR STATUS AMONG THE UNIVERSITY OF CALABAR UNDERGRADUATES, NIGERIA [PDF]

Sanamed
Introduction: Secretor status is a critical component of human biology that depends on specific glycoproteins in body fluids and secretions. Its importance lies in its significant impact on health and disease, making it a compelling subject for medical ...
Etura Joyce, Abam John, Akpan Uwem, Jeremiah Zaccheaus   +3 more
doaj   +1 more source