Results 81 to 90 of about 211,192 (311)

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Investigating the functionality and antigenicity of chimeric lyssavirus glycoproteins and their neutralisation profiles [PDF]

, 2013
Rabies, the archetypal lyssavirus, is one of the most feared viruses known to man and globally, is the cause of more than 50,000 deaths per year. Alongside rabies virus, numerous related lyssaviruses exist that are also capable of causing fatal clinical ...
Fooks, A.R., Wright, E., Banyard, A.C., Evans, J., Easton, A.   +4 more
core  

Recognition of viral glycoproteins by influenza A-specific cross- reactive cytolytic T lymphocytes [PDF]

, 1980
Two populations of cytolytic T lymphocytes (CTL) generated after influenza A virus infection can be distinguished into one with specificity for the sensitizing hemagglutinin type and a second with cross-reactivity for antigens induced by other type-A ...
Klenk, H, Gething, M. J., Koszinowski, Ulrich H., Gething, MJ, Waterfield, MD, M D Waterfield, U H Koszinowski, M J Gething, Koszinowski, UH, Klenk, H. D., H Allen, Allen, H, Gething, M, Koszinowski, U H, H D Klenk, Allen, H., Waterfield, M. D., Klenk, HD   +17 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Halobacterial flagellins are sulfated glycoproteins [PDF]

, 1985
The cell-surface glycoprotein of Halobacteria contains oligosaccharides of the type Glc4----1GlcA4----1GlcA4----1GlcA (where GlcA indicates glucuronic acid) with a sulfate group attached to each of the GlcA residues.
Sumper, Manfred, Wieland, F., Pauli, G.
core   +1 more source

Identification of Chemoresistance-Related Cell-Surface Glycoproteins in Leukemia Cells and Functional Validation of Candidate Glycoproteins [PDF]

, 2016
Chemoresistance remains the most significant obstacle to successful chemotherapy for leukemia, and its exact mechanism is still unknown. In this work, we used the cell-surface capturing method together with quantitative proteomics to investigate ...
Jiaqiang Dong (1837888), Zhengyan Hu (1837891), Kai Cheng (539804), Hanfa Zou (19660), Mingliang Ye (19659), Daiming Fan (124057), Zhen Sun (269397), Bo Xu (233514), Yongzhan Nie (124038), Song Zhang (180477), Kai Li (205203)   +10 more
core   +3 more sources

Loss of Kex2 Affects the Candida albicans Cell Wall and Interaction with Innate Immune Cells

Journal of Fungi, 2020
The secretory pathway in Candida albicans involves the protein translocation into the lumen of the endoplasmic reticulum and transport to the Golgi complex, where proteins undergo posttranslational modifications, including glycosylation and proteolysis ...
Manuela Gómez-Gaviria, Nancy E. Lozoya-Pérez, Monika Staniszewska, Bernardo Franco, Gustavo A. Niño-Vega, Hector M. Mora-Montes   +5 more
doaj   +1 more source

Bacterial Glycoproteins [PDF]

, 2002
115-119A large number of glycoprotein s are distributed in eukaryotic cells and their details are well documented. However, knowledge pertaining to prokaryotic glycoproteins is comparatively rare.
Upreti, Raj Kumar
core  

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem, Angel Liu, Sargis Manukyan, Mustafa Subhi, Elaina Luskin, Bryan Quah, Sreekanth Madhusoodhanan Nair, Arzu C. Has Silemek, Gabriela Zabala, Yujie Cui, Laura Locke, Paula Barreras, Marwa Kaisey, Vinicius Calsavara, Daniel S. Reich, Nancy L. Sicotte, Pascal Sati, Omar Al‐Louzi   +17 more
wiley   +1 more source