Results 81 to 90 of about 8,639 (159)

Glycopyrrolate abolishes the exercise-induced increase in cerebral perfusion in humans

, 2010
Brain blood vessels contain muscarinic receptors that are important for cerebral blood flow (CBF) regulation, but whether a cholinergic receptor mechanism is involved in the exercise-induced increase in cerebral perfusion or affects cerebral metabolism ...
Fisher, James P, Young, Colin N, Peter B. Raven, Paul J. Fadel, Secher, Niels H, Doreen Hartwich, Shigehiko Ogoh, Raven, Peter B, Fadel, Paul J, Fadel, PJ, Thomas Seifert, Seifert, Thomas, Young, CN, Raven, PB, Secher, NH, Seifert, T, Niels H. Secher, Ogoh, S, Colin N. Young, Ogoh, Shigehiko, Hartwich, Doreen, James P. Fisher, Fisher, James   +22 more
core   +1 more source

Anticholinergic treatments for focal and generalized hyperhidrosis

JAAD Reviews
Hyperhidrosis is a condition characterized by excessive and uncontrollable sweating that can significantly impact a patient’s physical, mental, and social qualities of life.
Mark Houdi, BA, Sahil Kapur, BS, Bassem Chamma, BS, Kermanjot Sidhu, BS, Emma Wolinsky, BA, Priyal Kancharla, BS, Craig G. Burkhart, MD   +6 more
doaj   +1 more source

Carry Over of Impurities: A Detailed Exemplification for Glycopyrrolate (NVA237)

, 2016
The original synthesis of glycopyrrolate (NVA237) was revised and shortened into an essentially one-pot process. Without isolating the intermediates, their purification became obsolete, thereby increasing the possibility of the carry over of impurities ...
Marco Manz (2023084), Regine Wicky (2023090), Dominique Bixel (2023093), Elena Gavioli (2023105), Laura Di Geronimo (2023087), Darko Valentekovic (2023081), Martin Schneider (101577), Thomas Allmendinger (2023096), Adrian Clarke (2023099), Fabien J. Stauffert (2023108), Jean-Wilfried Fredy (2023078), Markus Tibi (2023102)   +11 more
core   +1 more source

Comparison of the Effects of Atropine and Glycopyrrolate on various End-Organs¹

, 1980
Atropine and glycopyrrolate (glycopyrronium bromide), a quaternary ammonium drug, were evaluated in volunteers following intramuscular administration with respect to effects on various end-organs with cholinergic innervation.
R K Mirakhur, J W Dundee
core   +1 more source

A Comparison of Prophylactic Intravenous Glycopyrrolate and Ephedrine in the Prevention of Spinal Induced Maternal Hypotension during Caesarean Section

, 2017
Background: Spinal anaesthesia is complicated by hypotension and bradycardia. There are many risk factors for bradycardia in parturients who present for caesarean section.
Idehen, H.O., Imarengiaye, C.A.
core   +1 more source

A bioanalytical method development and validation for quantification of glycopyrrolate and neostigmine in rat plasma by LC-MS and its application to pharmacokinetic study

Journal of Applied Pharmaceutical Research
Background: After surgery, non-depolarizing neuromuscular blocking medications include neostigmine (NEO) and glycopyrrolate (GLY). Numerous traditional approaches, such as HPLC and UPLC procedures, are established for the quantification of GLY and NEO ...
P. Vasu Babu, D. Akiladevi
doaj   +1 more source

The Effect of Baseline Rescue Medication Use on Efficacy and Safety of Nebulized Glycopyrrolate Treatment in Patients with COPD from the GOLDEN 3 and 4 Studies [Corrigendum]

International Journal of COPD, 2020
Donohue JF, Ozol-Godfrey A, Goodin T, Sanjar S. Int J Chron Obstruct Pulmon Dis. 2020;15:745–754. The authors have advised there is an error in Figure 4 on page 751. The Q2 subgroup of the placebo arm has the label of “−0.
Donohue JF, Ozol-Godfrey A, Goodin T, Sanjar S   +3 more
doaj  

Hemodynamic effects of atropine and glycopyrrolate in isoflurane-xylazine-anesthetized dogs

The purpose of this study was to evaluate and compare the haemodynamic changes caused by the administration of i.v. atropine or glycopyrrolate after i.v. xylazine in isoflurane-anaesthetized dogs.

core   +1 more source

Cost-effectiveness of twice-daily indacaterol/glycopyrrolate inhalation powder for the treatment of moderate to severe COPD in the US

International Journal of COPD, 2018
Krithika Rajagopalan,1 Lisa Bloudek,2 Jessica Marvel,3 Carole Dembek,1 Abhishek Kavati3 1Sunovion Pharmaceuticals Inc., Marlborough, MA 01752, USA; 2Curta Inc., Seattle, WA 98116, USA; 3Novartis Pharmaceuticals Corporation, East Hanover, NJ 07936, USA ...
Rajagopalan K, Bloudek L, Marvel J, Dembek C, Kavati A   +4 more
doaj  

Comparative evaluation of zoletil and propofol induction in glycopyrrolate-xylazine-butorphanol premedicated dogs under isoflurane anaesthesia

The aim of this study was to evaluate two anaesthetic protocols in mixed-breed canine patients. Twelve dogs were randomly allocated into two groups, A and B, with six animals in each group.
Aarzoo Goswami, Surbhi K. Tyagi, Shubham Chaudhary, V. Malik   +3 more
core   +1 more source