Results 31 to 40 of about 88,938 (144)

A novel model-based approach for dose determination of glycopyrronium bromide in COPD

BMC Pulmonary Medicine, 2012
Background Glycopyrronium bromide (NVA237) is an inhaled long-acting muscarinic antagonist in development for treatment of COPD. This study compared the efficacy and safety of once-daily (OD) and twice-daily (BID) glycopyrronium bromide regimens, using a
Arievich Helen, Overend Tim, Renard Didier, Gibbs Michael, Alagappan Vijay, Looby Michael, Banerji Donald   +6 more
doaj   +1 more source

Randomised, double-blind, placebo-controlled trial of glycopyrronium in children and adolescents with severe sialorrhoea and neurodisabilities: protocol of the SALIVA trial

BMJ Paediatrics Open, 2023
Introduction Severe sialorrhoea is a common, distressing problem in children/adolescents with neurodisabilities, which has adverse health and social consequences.
Denis Pouchain, Stéphane Auvin, Helen Shaw, Nathalie Texier, Pierre Fayoux, Mickael Dinomais, Nick Probert, Frédéric Villain   +7 more
doaj   +1 more source

Growing season methyl bromide and methyl chloride fluxes at a sub-arctic wetland in Sweden [PDF]

, 2009
Methyl bromide and methyl chloride fluxes were measured at several sites in a sub-arctic wetland near Abisko, Sweden (68°280N 18°490E) throughout the 2008 growing season.
Blei, Emanuel, Heal, Mathew R., Heal, Mathew R, M. R. Heal, Heal, M. R.; id_orcid, C. J. Hardacre, Hardacre, Catherine J., E. Blei, Hardacre, C. J., Hardacre, Catherine, Blei, E.   +10 more
core   +5 more sources

The in vitro and in vivo profile of aclidinium bromide in comparison with glycopyrronium bromide [PDF]

, 2014
This study characterised the in vitro and in vivo profiles of two novel long-acting muscarinic antagonists, aclidinium bromide and glycopyrronium bromide, using tiotropium bromide and ipratropium bromide as comparators.
Ramos, Israel, Otal, Raquel, Beleta, Jorge, Alberti, Joan, Miralpeix, Montserrat, Sentellas, Sonia, Aparici, Monica, Vilella, Dolors, Carcasona, Carla, Montero, José Luis, Calama, Elena, Gavaldà, Amadeu   +11 more
core   +1 more source

EVALUATION OF EFFECTIVENESS OF ACLIDINIUM BROMIDE FOR PATIENTS WITH OCCUPATIONAL CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD)

Наука и инновации в медицине, 2017
Aim - evaluation of effectiveness and safety of the innovative medicinal product aclidinium bromide for patients with occupational COPD (chronic obstructive pulmonary disease). Materials and methods.
NV V Vakurova, TA A Azovskova
doaj   +1 more source

A comparative study on efficacy and safety of glycopyrronium bromide + salmeterol/fluticasone and tiotropium bromide + salmeterol/fluticasone in chronic obstructive pulmonary disease [PDF]

, 2019
Objective: To compare the effect of tiotropium bromide and glycopyrronium bromide in the treatment of chronic obstructive pulmonary disease. Methods: This was an open labeled Randomized controlled trial study.
Srivastava, Rahul, Ghosh, Dibyadeb, Kumar, Deepak, Khare, A.K., Raman, Ram Babu   +4 more
core   +1 more source

When single-inhaler triple therapy is a preferred option in asthma management?

Annals of Thoracic Medicine, 2022
Asthma control is the main goal of management. Unfortunately, most asthma patients with moderate–severe asthma remain uncontrolled despite receiving standard treatment of inhaled corticosteroids (ICS) with long-acting β2 agonists (LABA).
Mohamed S Al-Moamary, Riyad Al-Lehebi, Majdy M Idrees, Mohammed O Zeitouni   +3 more
doaj   +1 more source

Dose bridging data for mometasone furoate in once-daily fixed-dose inhaled combinations of mometasone furoate/indacaterol and mometasone furoate/ indacaterol/glycopyrronium in patients with asthma [PDF]

, 2021
Once-daily (o.d.) fixed-dose combinations of mometasone furoate/indacaterol acetate and mometasone furoate/indacaterol acetate/glycopyrronium bromide, both delivered via the Breezhaler® device, are approved for the maintenance treatment of asthma. Across
Jauernig, Juergen, Kerstjens, Huib A M; id_orcid, Kerstjens, Huib A M, Nikolaev, Ivan, Bartels, Christian, Tillmann, Hanns-Christian, Vaidya, Soniya, Jain, Monish, Buhl, Roland   +8 more
core   +2 more sources

A Novel Stability-Indicating Method for Simultaneous Estimation of Glycopyrronium Bromide and Neostigmine Methyl Sulfate Injectable Formulations by RP-HPLC

Indonesian Journal of Chemistry
Glycopyrronium bromide and neostigmine methyl sulfate drugs combination is used in treatment as an injectable formulation. The present study proposes the development and validation of an accurate, selective, and sensitive RP-HPLC method, which will ...
Chetankumar Mashru, Jayesh Dhalani
doaj   +1 more source

The discovery and development of ensifentrine: A novel inhaled dual PDE3/4 inhibitor having ‘bifunctional’ bronchodilator and anti‐inflammatory activity

British Journal of Pharmacology, EarlyView.
Abstract Ensifentrine (formerly called RPL 554) is a novel, first in class, inhaled bifunctional dual PDE3/4 inhibitor for the treatment of chronic respiratory diseases. Ensifentrine exhibits both bronchodilation via PDE3 inhibition and anti‐inflammatory activity via PDE4 inhibition.
Clive Page
wiley   +1 more source