Results 41 to 50 of about 88,938 (144)

The efficacy and safety of glycopyrronium bromide for the treatment of chronic obstructive pulmonary disease: A protocol for systematic review and meta-analysis

, 2021
To assess the efficacy and safety of glycopyrronium bromide for the treatment of chronic obstructive pulmonary disease (COPD)
Yonghong Xiang
core   +1 more source

A 1% glycopyrronium bromide cream for topical treatment of severe primary axillary hyperhidrosis in adolescents: safety, local tolerability, systemic exposure and efficacy from an open‐label phase II study

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objectives Primary axillary hyperhidrosis (PAHH) results from dysregulation of the autonomic nervous system and typically begins during puberty. Treatment options for adolescents remain limited. This open‐label phase II study evaluated the safety, local tolerability, systemic exposure, and efficacy of 1% GPB cream over 8 weeks in
Rolf‐Markus Szeimies, Ana Kilic, Hubert Reich, Birgit Berger, Erik Schulze zur Wiesche, Leonie Litzka, Katharina Schramm, Susanne Heimstaedt‐Muskett, Clarissa Masur   +8 more
wiley   +1 more source

Glycopyrronium bromide for the treatment of chronic obstructive pulmonary disease

, 2015
Glycopyrronium bromide is a new long-acting muscarinic antagonist to be used once-daily, which is approved as a bronchodilator for the symptomatic maintenance treatment of adult patients with chronic obstructive pulmonary disease (COPD).
Riario Sforza, Gian Galeazzo, RIDOLO, Erminia, Incorvaia, Cristoforo, Riario Sforza, Edoardo   +3 more
core   +1 more source

Long-acting muscarinic antagonists for the prevention of exacerbations of chronic obstructive pulmonary disease

Therapeutic Advances in Respiratory Disease, 2015
Exacerbations of chronic obstructive pulmonary disease (COPD) have important consequences for lung function, health status and mortality. Furthermore, they are associated with high economic costs, predominantly related to hospitalization.
Paul W. Jones
doaj   +1 more source

Oral Health Care Services, Barriers and Enablers to Maintaining Good Oral Health in Motor Neurone Disease: A Scoping Review

Community Dentistry and Oral Epidemiology, Volume 54, Issue 4, Page 447-461, August 2026.
ABSTRACT Objectives The objective of this scoping review was to map existing literature on oral health and related care in individuals with Motor Neurone Disease (MND). Specifically, the review aimed to identify barriers and facilitators to maintaining oral hygiene, summarise available clinical guidelines and patient‐facing resources, and examine how ...
Mariam A. Khokhar, Lucy A. O'Malley, Anne‐Marie Glenny, Xiaohui Chen   +3 more
wiley   +1 more source

Pharmacological investigations on muscarinic and P2 receptor subtypes : pharmacological charakterisation of the stereoisomers of glycopyrronium bromide and their tertiary analogues and evaluation of the isolated guinea-pig and rat ileal longitudinal [PDF]

, 2003
Die Beschäftigung mit Muskarinrezeptoren reicht bis in das vergangene Jahrhundert zurück als, in Folge der verschiedenen Wirkungen des Neurotransmitters Acetylcholin, einerseits Nikotin- und andererseits Muskarinrezeptoren sowie deren Subtypen entdeckt ...
Czeche, Sittah
core  

Use of oral glycopyrronium bromide in hyperhidrosis

Background Idiopathic hyperhidrosis may be a disabling condition causing emotional stress and negative impact on a patient\u27s quality of life. Oral anticholinergics are one of the treatments available.
Langtry JAA, Bajaj V
core   +5 more sources

Identification of Mepenzolate Derivatives With Long-Acting Bronchodilatory Activity

Frontiers in Pharmacology, 2018
The standard treatment for chronic obstructive pulmonary disease is a combination of anti-inflammatory drugs and bronchodilators. We recently found that mepenzolate bromide (MP), an antagonist for human muscarinic M3 receptor (hM3R), has both anti ...
Ken-Ichiro Tanaka, Naoki Yamakawa, Yasunobu Yamashita, Teita Asano, Yuki Kanda, Ayaka Takafuji, Masahiro Kawahara, Mitsuko Takenaga, Yoshifumi Fukunishi, Tohru Mizushima   +9 more
doaj   +1 more source

Skin Acceptability of a Topical Cream Containing Zinc Oxide, Zinc Gluconate, Taurine and Panthenol in Females With Urinary Incontinence

Journal of Cosmetic Dermatology, Volume 25, Issue 8, August 2026.
ABSTRACT Background Incontinence‐associated dermatitis (IAD) can be exacerbated by friction and occlusion from a diaper/incontinence pad. Skin barrier function in IAD can be preserved through humectant and emollient‐containing protective agents. Aims To investigate the efficacy, skin acceptability, and cosmetic qualities of a cream containing zinc ...
Leonardo Celleno, Linda Landini, Dalia Mostafa Kamal, Fabrizio Mazzicone   +3 more
wiley   +1 more source

Effect of glycopyrronium bromide on basal, and histamine- or gastrin-induced gastric secretion

, 1969
Acid secretory responses were obtained in rats given either intravenous histamine as dihydrochloride or gastrin subjected to partial purification. A continuous recording method for measuring gastric acid secretion was used.
B O Amure
core   +1 more source