Results 61 to 70 of about 88,938 (144)

Clinical Application Guideline of Combination With Traditional Chinese Medicine and Western Medicine in the Prevention and Treatment of Chronic Obstructive Pulmonary Disease (2024)

Journal of Evidence-Based Medicine, Volume 18, Issue 2, June 2025.
ABSTRACT Aim Chronic Obstructive Pulmonary Disease (COPD) is a common chronic airway disease that can lead to decreased lung function in patients. It places a heavy economic burden on patients and society. Traditional Chinese medicine (TCM) and Western medicine have played important roles in managing COPD.
Di Wu, Wei Liu, Jianxin Wang, Wei Chen, Mengyao Shi, Lu Zhang, Hui Wang, Huanzhang Ding, Xiao Ma, Yating Gao, Zengtao Sun, Jiangtao Lin, Hongchun Zhang, Suyun Li, Zhuying Li, Zhenhui Lu, Fuqiang Wen, Zegeng Li   +17 more
wiley   +1 more source

The effect of glycopyrronium bromide on nocturnal clozapineinduced sialorrhoea in psychiatric patients [PDF]

, 2015
OBJECTIVE: To determine the effect of oral glycopyrronium bromide in comparison with placebo on the severity of complaints of nocturnal sialorrhoea in psychiatric patients treated with clozapine and also in a subset of patients using a double dose of ...
Wilting, I., Sub Clinical Pharmacy, Pharmacoepi, Colen-De Koning, J. C A, Van Haelst, I. M M, Cahn, W., Cahn, W, Schulte, PFJ, Schulte, P. F J, Egberts, A. C G, Wilting, I, Egberts, ACG, Man, W. H., Heerdink, E.R., Man, WH, Pharmacoepidemiology and Clinical Pharmacology, Doodeman, H.J., Doodeman, H. J., Colen-de Koning, Jantien, Heerdink, E. R., van Haelst, I.M.M.   +19 more
core   +1 more source

Efficacy and Safety of Treatments for Primary Palmar Hyperhidrosis: A Systematic Review Assessing Patient‐Centric Outcomes

Dermatology Research and Practice, Volume 2025, Issue 1, 2025.
Background: Primary palmar hyperhidrosis (PH) is a chronic condition characterized by excessive sweating in the palms, significantly affecting the quality of life (QOL) of affected individuals. Despite the availability of various treatment modalities, the long‐term efficacy and safety of these interventions remain unclear, warranting a comprehensive ...
Foteini Moniati, Marianna Vassiliou, Christos Costa, Constantina Chatzimatthaiou, Marios Chatzimatthaiou, Craig G. Burkhart   +5 more
wiley   +1 more source

Efficacy and Safety of Glycopyrronium Bromide 1% Cream in Axillary and Extra‐Axillary Primary Hyperhidrosis: A Real‐Life Two‐Center Experience on 68 Subjects

Dermatologic Therapy, Volume 2025, Issue 1, 2025.
Introduction: Primary hyperhidrosis (PH) is a common disorder affecting approximately 1% of the general population, characterized by focal sweating in excess of that required for normal temperature regulation without any associated condition. It is an embarrassing and disabling condition with a great impact on patients’ quality of life.
Helena Gioacchini, Andrea Marani, Federico Diotallevi, Agnese Rossi, Sara Lambiase, Virginia Maffei, Luca Bianchi, Elena Campione, Anna Campanati, Suraiya Saleem   +9 more
wiley   +1 more source

The Real‐World Analysis of Adverse Events With Two Types of Single‐Inhaler Triple Therapy: A VigiAccess Database Study

Journal of Clinical Pharmacy and Therapeutics, Volume 2025, Issue 1, 2025.
Background The advent of single‐inhaler triple therapies (SITTs), including fluticasone furoate/umeclidinium/vilanterol (FF/UMEC/VI) and beclomethasone dipropionate/formoterol fumarate/glycopyrronium bromide (BDP/FOR/GLY), has expanded treatment options for chronic obstructive pulmonary disease (COPD).
Baiquan Zhang, Jiayu Bai, Lu Zhou, Hongda Liu   +3 more
wiley   +1 more source

A randomised, double-blind, active placebo-controlled, parallel groups, dose-response study of scopolamine hydrobromide (4–6 μg/kg) in patients with major depressive disorder

Trials, 2020
Background Depressive disorders are a leading cause of disability, but current behavioural and pharmacological therapies have a slow onset of response, typically taking several weeks before achieving efficacy.
Joseph C. C. Chen, Rachael L. Sumner, Venkat Krishnamurthy Naga, Nicholas Hoeh, Hafis Adetokunbo Ayeni, Vikrant Singh, Frederick Sundram, Douglas Campbell, Suresh Muthukumaraswamy   +8 more
doaj   +1 more source

Drugs Used in the Treatment of Viral Infections for the Prevention of Airway Remodeling in Asthma

Mediators of Inflammation, Volume 2025, Issue 1, 2025.
One of the main causes of the exacerbation of chronic airway inflammatory diseases is respiratory virus infections. The most prevalent viruses that can infect humans multiple times a year are rhinovirus (RV) and respiratory syncytial virus (RSV). Because remodeling factors like matrix metalloproteinases (MMPs), which are released by infiltrating ...
Joanna Wieczfinska, Rafal Pawliczak, Mirella Giovarelli   +2 more
wiley   +1 more source

Implications of the non‐neuronal cholinergic system for therapeutic interventions of inflammatory skin diseases

Experimental Dermatology, Volume 33, Issue 10, October 2024.
Abstract The pivotal roles of acetylcholine (ACh) in physiological processes encompass both the nervous and non‐neuronal cholinergic systems (NNCS). This review delineates the synthesis, release, receptor interactions, and degradation of ACh within the nervous system, and explores the NNCS in depth within skin cells including keratinocytes, endothelial
Hui‐Qi Qu, Charlly Kao, Hakon Hakonarson   +2 more
wiley   +1 more source

Profile of glycopyrronium for once-daily treatment of moderate-to-severe COPD

International Journal of COPD, 2012
Roland Buhl,1 Donald Banerji21Pulmonary Department, Mainz University Hospital, Mainz, Germany; 2Novartis Pharmaceuticals Corporation, East Hanover, NJ, USAAbstract: Bronchodilators are central in the symptomatic management of chronic obstructive ...
Buhl R, Banerji D
doaj  

Investigating the Heterogeneity of “Study Twins”

Biometrical Journal, Volume 66, Issue 6, September 2024.
ABSTRACT Meta‐analyses are commonly performed based on random‐effects models, while in certain cases one might also argue in favor of a common‐effect model. One such case may be given by the example of two “study twins” that are performed according to a common (or at least very similar) protocol. Here we investigate the particular case of meta‐analysis
Christian Röver, Tim Friede
wiley   +1 more source