Results 261 to 270 of about 116,862 (285)

Monitoring T-Cell Activation in the Tumor Microenvironment by PET Imaging of the Chemokine CXCL9. [PDF]

J Nucl Med
Jacobson O, Zhang HH, Olkowski CP, Ghaemi B, Basuli F, Shi J, Bell MM, Parween F, Ganesan S, Esparza TJ, Escorcia FE, Choyke PL, Farber JM.   +12 more
europepmc   +1 more source

The Expanding Role of Gene Sequencing in Shaping Fetal Therapies: Clinical and Ethical Considerations

Prenatal Diagnosis, EarlyView.
ABSTRACT In utero interventions are transformative in addressing genetic and anatomic conditions during fetal development. Next generation sequencing enables early genetic testing, playing a pivotal role in prenatal decision‐making by supporting risk stratification, precise and timely diagnosis, which directly informs eligibility for fetal surgical and
Matthew A. Shear, Beltran Borges, Billie R. Lianoglou, Tony Lum, Emma Canepa, Jennifer L. Cohen, Julia E. H. Brown, Akos Herzeg   +7 more
wiley   +1 more source

A synthetic glycosaminoglycan reduces sinonasal inflammation in a murine model of chronic rhinosinusitis

, 2018
Jeremiah A. Alt, Won Yong Lee, Brock Davis, Justin R. Savage, Thomas P. Kennedy, Glenn D. Prestwich, Abigail Pulsipher   +6 more
openalex   +2 more sources

Sample Preparation for Multi‐Omics Analysis: Considerations and Guidance for Identifying the Ideal Workflow

PROTEOMICS, EarlyView.
ABSTRACT Advances in methodologies and technologies over the past decade have led to an unprecedented depth of analysis of a cell's biomolecules, with entire genomes able to be sequenced in hours and up to 10,000 transcripts or ORF products (proteins) able to be quantified from a single cell.
Breyer Woodland, Luke A. Farrell, Lana Brockbals, Maria Rezcallah, Aiden Brennan, Emily J. Sunnucks, Sam T. Gould, Aleksandra M. Stanczak, Matthew B. O'Rourke, Matthew P. Padula   +9 more
wiley   +1 more source

An effective approach to cartilage regeneration using antler stem cell-conditioned medium. [PDF]

Sci Rep
Zhou J, Xing B, Guo Q, Zhao J, Li X, Wang D, Yue Z, Lv J, Jiang Y, Sun H.   +9 more
europepmc   +1 more source

Exploring relationships between tumor mutation burden with immunity and prognosis in lung adenocarcinoma based on weighted gene co‐expression network analysis

Precision Medical Sciences, EarlyView.
This study reveals that high TMB in lung adenocarcinoma correlates with better survival prognosis and lower immune/stromal scores. Through WGCNA and consensus clustering, we identify two LUAD subtypes with distinct prognoses and mutation frequencies, offering novel insights for immunotherapy response prediction and prognosis stratification.
Haiyong Wu, Jinzhuo Ren, Zhipeng Gong, Yan Zhang, Hua Zhang, Weikang Chen, Chenyang Zhao, Tao Fang   +7 more
wiley   +1 more source

Novel Phenotypic Insights into the <i>IDS</i> c.817C>T Variant in Mucopolysaccharidosis Type II from Newborn Screening Cohorts. [PDF]

Int J Neonatal Screen
Beauregard-Lacroix É, Menello C, Steffensen M, Lin HY, Chuang CK, Lin SP, Ficicioglu C.   +6 more
europepmc   +1 more source

Iterative Modeling via Structural Diffusion (IMSD): Exploring Fold‐Switching Pathways in Metamorphic Proteins Using AlphaFold2‐Based Generative Diffusion Model UFConf

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Metamorphic proteins (MPs) can fold into two or more distinct spatial structures. Increasing interest in MPs has spurred the search for computational tools to predict proteins fold‐switching potential and model their refolding pathways. Here we address this problem by using the recently reported generative diffusion predictor UFConf, based on ...
Dmitrii A. Luzik, Nikolai R. Skrynnikov
wiley   +1 more source