Results 51 to 60 of about 87,711 (206)
A very common mechanism to trap pathogens is the release of DNA. Like flies in a spider's web, pathogens are enclosed in a sticky chromatin meshwork. Interestingly, plants already use this mechanism to catch bacteria.
Kim F. Bornhöfft, Sebastian P. Galuska
doaj +1 more source
Visual histological grading system for the evaluation of in vitro-generated neocartilage [PDF]
Here we present the development of a visual evaluation system for routine assessment of in vitro-engineered cartilaginous tissue. Neocartilage was produced by culturing human articular chondrocytes in pellet culture systems or in a scaffold-free ...
Barbero, Andrea+7 more
core +1 more source
Mucopolysaccharidoses (MPS) and mucolipidosis (ML II/III) are a group of lysosomal storage disorders (LSDs) that occur due to a dysfunction of the lysosomal hydrolases responsible for the catabolism of glycosaminoglycans (GAGs).
Nivethitha Arunkumar+14 more
doaj +1 more source
Glycosaminoglycan-Based Cryogels as Scaffolds for Cell Cultivation and Tissue Regeneration
Cryogels are a class of macroporous, interconnective hydrogels polymerized at sub-zero temperatures forming mechanically robust, elastic networks. In this review, latest advances of cryogels containing mainly glycosaminoglycans (GAGs) or composites of ...
Annika Wartenberg+2 more
doaj +1 more source
New Applications of Heparin and Other Glycosaminoglycans
Heparin, the widely used pharmaceutical anticoagulant, has been in clinical use for well over half a century. Its introduction reduced clotting risks substantially and subsequent developments, including the introduction of low-molecular-weight heparin ...
M. Lima, T. Rudd, E. Yates
semanticscholar +1 more source
Transcriptome-based reconstructions from the murine knockout suggest involvement of the urate transporter, URAT1 (slc22a12), in novel metabolic pathways. [PDF]
URAT1 (slc22a12) was identified as the transporter responsible for renal reabsorption of the medically important compound, uric acid. However, subsequent studies have indicated that other transporters make contributions to this process, and that URAT1 ...
Eraly, Satish A+3 more
core +2 more sources
Cellular Aspects of Prion Replication In Vitro
Prion diseases or transmissible spongiform encephalopathies (TSEs) are fatal neurodegenerative disorders in mammals that are caused by unconventional agents predominantly composed of aggregated misfolded prion protein (PrP).
Ina Vorberg+4 more
doaj +1 more source
Mast cells contain granules packed with a mixture of proteins that are released on degranulation. The proteoglycan serglycin carries an array of glycosaminoglycan (GAG) side chains, sometimes heparin, sometimes chondroitin or dermatan sulphate.
B. Mulloy, R. Lever, C. Page
semanticscholar +1 more source
Roles of Proteoglycans and Glycosaminoglycans in Wound Healing and Fibrosis
A wound is a type of injury that damages living tissues. In this review, we will be referring mainly to healing responses in the organs including skin and the lungs.
S. Ghatak+7 more
semanticscholar +1 more source
Remodeling Of The Bone Tissue Of Rats Of Different Lines After Melatonin Effect [PDF]
The markers of remodeling of bone tissue (BT) were studied after the impact of pharmacologic dose of melatonin (5 mg/kg of the animal body weight) during 28 days for 3-months rats-males of Wistar and SHR lines.
Berezovskyi, V. (Vadim)+2 more
core +2 more sources