Results 51 to 60 of about 52,449 (293)

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

Advanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana, Indra Apsite, Leonid Ionov   +2 more
wiley   +1 more source

Glycosaminoglycans in Scleroderma and Scleredema

Journal of Investigative Dermatology, 1972
Skin from 6 patients with scleroderma, 3 with scleredema and 5 normal controls were subjected to qualitative and quantitative analysis of glycosaminoglycans. Glycosaminoglycans were identified by cetylpyridinium chloride-salt fractionation and by cellulose acetate electrophoresis.
Jerome S. Perlish, Raul Fleischmajer
openaire   +3 more sources

Versatile Cell Penetrating Peptide for Multimodal CRISPR Gene Editing in Primary Stem Cells

Advanced Functional Materials, EarlyView.
CRISPR machinery in diverse molecular formats (DNA, RNA, and ribonucleic protein) is complexed into nanoparticles with the cell‐friendly arginine‐alanine‐leucine‐alanine (RALA) cell‐penetrating peptide. Nanoparticles are delivered to primary mesenchymal stem cells ex vivo or locally in vivo to facilitate multimodal CRISPR gene editing. This RALA‐CRISPR
Joshua P. Graham, Jose Gabriel Castro, Lisette C. Werba, Joseph Amitrano, Luke Fardone, Kevin P. Francis, Anand Ramamurthi, Michael J. Layden, Helen O. McCarthy, Tomas Gonzalez‐Fernandez   +9 more
wiley   +1 more source

Natural Presentation of Glycosaminoglycans in Synthetic Matrices for 3D Angiogenesis Models

Frontiers in Cell and Developmental Biology, 2021
Glycosaminoglycans (GAGs) are long, linear polysaccharides that occur in the extracellular matrix of higher organisms and are either covalently attached to protein cores, as proteoglycans or in free form.
Cornelia Zapp, Cornelia Zapp, Patricia Mundinger, Patricia Mundinger, Heike Boehm, Heike Boehm   +5 more
doaj   +1 more source

Dermal Glycosaminoglycans in Psoriasis

Journal of Investigative Dermatology, 1970
Six dermal specimens from active plaques of psoriasis were subjected to biochemical analysis of glycosaminoglycans. The technique used consisted of digestion of the dermal samples with papain and trypsin, uronic acid determination by the carbazol method and identification of hyaluronic acid (HA) and dermatan sulfate (DS) by cellulose acetate ...
T. Piamphongsant, A. Burgoyne, Raul Fleischmajer   +2 more
openaire   +3 more sources

Glycosaminoglycans in horses with osteoarthritis [PDF]

Equine Veterinary Journal, 1991
SummaryHorse articular cartilage glycosaminoglycans (GAGs) were measured in synovial fluids from 48 joints affected with osteoarthritis (OA), 22 normal joints, four joints with osteochondritis, three joints with traumatic arthritis and seven joints infected with bacteria.
W.H. Alwan, G. B. Edwards, D. Bennett, Stuart D. Carter   +3 more
openaire   +3 more sources

Matrix Tropism Influences Endometriotic Cell Attachment Patterns

Advanced Functional Materials, EarlyView.
The influence of substrate stiffness and multicellular coculture on endometriotic cell attachment to extracellular matrix‐laden microarrayed islands is reported. This model investigates early endometriotic cell attachment, aiming to capture “lesion initiation events”.
Hannah S. Theriault, Hannah R.C. Kimmel, Alison C. Nunes, Allison L. Paxhia, Sarah Hashim, Kathryn B.H. Clancy, Gregory H. Underhill, Brendan A.C. Harley   +7 more
wiley   +1 more source

Regional Variation in Androgen Receptor Expression and Biomechanical Properties May Contribute to Cryptorchidism Susceptibility in the LE/orl Rat

Frontiers in Endocrinology, 2018
Background: The process of testicular descent requires androgen and insulin-like 3, hormones secreted by fetal Leydig cells. Knowledge concerning distinct and common functions of these hormones in regulating development of the fetal gubernaculum remains ...
Joshua T. Morgan, Alan K. Robbins, Abigail B. Mateson, Kazuki Sawamoto, Shunji Tomatsu, Dione R. Gray, Jason P. Gleghorn, Julia Spencer Barthold   +7 more
doaj   +1 more source

Advances in glycosaminoglycan detection

Molecular Genetics and Metabolism, 2020
Glycosaminoglycans (GAGs) are negatively charged long linear (highly sulfated) polysaccharides consisting of repeating disaccharide units that are expressed on the surfaces of all nucleated cells. The expression of GAGs is required for embryogenesis, regulation of cell growth and proliferation, maintenance of tissue hydration, and interactions of the ...
Hironori Kobayashi, Shunji Tomatsu, Robert W. Mason, Shaukat Khan, Seiji Yamaguchi   +4 more
openaire   +4 more sources

Embedded 3D‐Coaxial Bioprinting of Stenotic Brain Vessels with a Mechanically Enhanced Extracellular Matrix Bioink for Investigating Hemodynamic Force‐Induced Endothelial Responses

Advanced Functional Materials, EarlyView.
In this study, a physically enhanced vascular dECM bioink and used 3D‐coaxial bioprinting are developed to fabricate mature brain blood vessels for cerebral atherosclerosis research. This model demonstrates that vascular geometry‐induced hemodynamic changes trigger vascular inflammation, ensuring its potential for cerebrovascular research.
Wonbin Park, Min‐Ju Choi, Jae‐Seong Lee, Minjun Ahn, Wonil Han, Ge Gao, Dong‐Woo Cho, Byoung Soo Kim   +7 more
wiley   +1 more source