Results 61 to 70 of about 60,454 (182)
Glycosaminoglycan–Protein Interactions: The First Draft of the Glycosaminoglycan Interactome [PDF]
Journal of Histochemistry & Cytochemistry, 2020 The six mammalian glycosaminoglycans (GAGs), chondroitin sulfate, dermatan sulfate, heparin, heparan sulfate, hyaluronan, and keratan sulfate, are linear polysaccharides. Except for hyaluronan, they are sulfated to various extent, and covalently attached to proteins to form proteoglycans.
Sylvain D, Vallet +2 more
openaire +2 more sources
Functionality of surface-coupled oxidised glycosaminoglycans towards fibroblast adhesion [PDF]
, 2016 Glycosaminoglycans are able to bind many growth factors and adhesive proteins, which affect cell activities such as adhesion, migration, growth and differentiation.
Yang, Y. +6 more
core +1 more source
Glycosaminoglycan-Based Cryogels as Scaffolds for Cell Cultivation and Tissue Regeneration
Molecules, 2021 Cryogels are a class of macroporous, interconnective hydrogels polymerized at sub-zero temperatures forming mechanically robust, elastic networks. In this review, latest advances of cryogels containing mainly glycosaminoglycans (GAGs) or composites of ...
Annika Wartenberg +2 more
doaj +1 more source
Biomedicines, 2021 In clinical studies, OM-85 Broncho-Vaxom®, a bacterial lysate, reduced viral respiratory tract infection. Infection of epithelial cells by SARS-CoV-2 depends on the interaction of its spike-protein (S-protein) with host cell membrane proteins.
Lei Fang +3 more
doaj +1 more source
Glycosaminoglycan Functionalized Nanoparticles Exploit Glycosaminoglycan Functions
, 2014 Nanoparticles are being explored for a variety of applications including medical imaging, drug delivery, and biochemical detection. Surface functionalization of nanoparticles with glycosaminoglycans (GAGs) is an attractive strategy that is only starting to be investigated to improve their properties for biological and therapeutic applications.
Vassie, JA, Whitelock, JM, Lord, MS
openaire +3 more sources
Glycosaminoglycans in gingival crevicular fluid of patients with periodontal class II furcation involvement before and after guided tissue regeneration. A pilot study [PDF]
, 2000 Background: The levels of glycosaminoglycans in gingival crevicular fluid (GCF) are good indicators of underlying tissue turnover. We hypothesize that connective tissue elements in GCF may be used as indicators of tissue maturation underneath barrier ...
P. Mark Bartold +13 more
core +1 more source
Metabolites, 2023 Mucopolysaccharidosis 1 (MPS 1) is a group of rare lysosomal genetic disorders resulting from the accumulation of undegraded glycosaminoglycans (GAGs) leading to multiorgan damage. Neurological symptoms vary from mild to severe.
Magdalena Machnikowska-Sokołowska +5 more
doaj +1 more source
Heparin modulates the endopeptidase activity of Leishmania mexicana cysteine protease cathepsin L-Like rCPB2.8 [PDF]
, 2013 Cysteine protease B is considered crucial for the survival and infectivity of the Leishmania in its human host. Several microorganism pathogens bind to the heparin-like glycosaminoglycans chains of proteoglycans at host-cell surface to promote their ...
Gesteira, Tarsis F. +11 more
core +3 more sources
Pharmaceutics, 2022 One of the main problems of modern health care is the growing number of oncological diseases both in the elderly and young population. Inadequately effective chemotherapy, which remains the main method of cancer control, is largely associated with the ...
Natalia Todosenko +5 more
doaj +1 more source
Marine Sourced Glycosaminoglycans ‘GAGs’ [PDF]
, 2014 Globally, there is an uprising interest for availability of tangible, novel, added value, sustainable commercial exploitable therapeutic compounds from naturally derived sources.
Ghazali, Farid C. +2 more
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