Results 51 to 60 of about 64,705 (285)

Norfloxacin-Loaded Electrospun Scaffolds: Montmorillonite Nanocomposite vs. Free Drug

open access: yesPharmaceutics, 2020
Infections in nonhealing wounds remain one of the major challenges. Recently, nanomedicine approach seems a valid option to overcome the antibiotic resistance mechanisms.
Angela Faccendini   +10 more
doaj   +1 more source

Chemokine‐Capturing Wound Contact Layer Rescues Dermal Healing

open access: yesAdvanced Science, 2021
Excessive inflammation often impedes the healing of chronic wounds. Scavenging of chemokines by multiarmed poly(ethylene glycol)‐glycosaminoglycan (starPEG‐GAG) hydrogels has recently been shown to support regeneration in a diabetic mouse chronic skin ...
Lucas Schirmer   +3 more
doaj   +1 more source

The multifaceted roles of lysosomes in cancer

open access: yesMolecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

Urinary excretion of oxalate, citrate, glycosaminoglycans in children with urolithiasis [PDF]

open access: yes, 2016
Analizirano je izlučivanje urinom oksalata, citrata i glikozaminoglikana u 83 djece s idiopatskom urolitijazom. Iz analize su isključene primarne hiperoksalurije i idiopatske hiperokslurije (HOGA 1) koje su uzrokovane mutacijama gena i enteričkom ...
Turudić, Daniel
core   +1 more source

Is Endothelial Nitric Oxide Synthase a Moonlighting Protein Whose Day Job is Cholesterol Sulfate Synthesis? Implications for Cholesterol Transport, Diabetes and Cardiovascular Disease

open access: yesEntropy, 2012
Theoretical inferences, based on biophysical, biochemical, and biosemiotic considerations, are related here to the pathogenesis of cardiovascular disease, diabetes, and other degenerative conditions.
Stephanie Seneff   +3 more
doaj   +1 more source

Mechanistic insights into molecular evolution of species-specific differential glycosaminoglycan binding surfaces in growth-related oncogene chemokines [PDF]

open access: yesRoyal Society Open Science, 2017
Chemokines are chemotactic cytokines involved in leucocyte trafficking to infected tissue. Growth-related oncogene (GRO) chemokines namely CXCL1, CXCL2 and CXCL3 are neutrophil activating chemokines sharing a conserved three-dimensional structure, but ...
Khushboo Gulati   +2 more
doaj   +1 more source

Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling

open access: yesFEBS Open Bio, EarlyView.
Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt   +2 more
wiley   +1 more source

Biodegradable Conductors for Implantable and Wearable Transient Bioelectronics

open access: yesAdvanced Functional Materials, EarlyView.
Biodegradable conductors are essential building blocks for transient bioelectronics, enabling temporary sensing, stimulation, and energy transfer while eliminating the need for device retrieval. This review summarizes biodegradable metals, conducting polymers, ionic conductors, and conductive composites, highlighting degradation mechanisms, material ...
Yicheng Zhu, Yijun Liu, Naoji Matsuhisa
wiley   +1 more source

Artemisinin‐Loaded Core‐Shell Microspheres Modulate Histone Lactylation to Remodel the Microenvironment for Cartilage Protection in Rheumatoid Arthritis

open access: yesAdvanced Healthcare Materials, EarlyView.
ART@PLGA@GH‐A microspheres are developed via microfluidic technology for intra‐articular delivery of artemisinin. The system remodels rheumatoid arthritis microenvironments by regulating metabolic and inflammatory disorders, reducing lactate‐driven histone lactylation and cellular senescence, while restoring cartilage homeostasis and protecting joint ...
Shijie Meng   +10 more
wiley   +1 more source

Influence of combined nitrate and fluoride intoxication on connective tissue disorders in rats gastric mucosa [PDF]

open access: yesArchives of the Balkan Medical Union, 2019
Introduction. Certain regions in Europe and Ukraine have high concentration of fluorides in drinking waters. Highly developed agriculture can result in increased concentration of nitrates in ground and drinking waters. Therefore, their combined excessive
Oleh Y. AKIMOV   +2 more
doaj   +1 more source

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