Results 81 to 90 of about 98,029 (348)

Diels‐Alder Click Chemistry as a Dynamic‐Covalent Crosslinking Method in Spheroid‐Encapsulating Hydrogels for Cartilage Engineering

Advanced Healthcare Materials, EarlyView.
This research shows the development of hydrogels with Diels‐Alder click chemistry for engineering cartilage‐like tissue. The hydrogels support cartilage spheroids which could be cultured for at least 28 days. Furthermore, the spheroids showed a tendency to fuse together into a more consistent construct, and produced important components needed for ...
Sanne M. van de Looij, Antonia G. Vasilopoulou, Lennard Spauwen, Antoinette van den Dikkenberg, Jasmijn V. Korpershoek, Mylene de Ruijter, Jos Malda, Bas G. P. van Ravensteijn, Tina Vermonden   +8 more
wiley   +1 more source

Synovial joint lubrication – does nature teach more effective engineering lubrication strategies? [PDF]

, 2007
Nature shows numerous examples of systems which show energy efficiency, elegance in their design and optimum use of materials. Biomimetics is an emerging field of research in engineering and successes have been documented in the diverse fields of ...
Liskiewicz, T., Morina, A., Neville, A., Yan, Y.   +3 more
core   +1 more source

Supramolecular Engineering of Fluid Pressure in Filamentous Hybrid Double Network Hydrogels for 3D Chondrocyte Culture

Advanced Healthcare Materials, EarlyView.
Inspired by the water‐rich and interconnected biopolymer networks of native load‐bearing tissues, we disclose a connectable design for a hybrid filamentous supramolecular and covalent double network hydrogel generated through in situ photopolymerization.
Ciqing Tong, Ying Chen, Merel L. Janssen, Isabel Sariol, Joeri A. J. Wondergem, Marijn van den Brink, Mertcan Özel, Rob G. H. H. Nelissen, Ingrid Meulenbelt, Doris Heinrich, Yolande F. M. Ramos, Roxanne E. Kieltyka   +11 more
wiley   +1 more source

Wound Geometry Determines Whether Aligned‐Fiber Scaffolds Accelerate or Impede Diabetic Wound Healing: A Biased Random Walk Analysis

Advanced Healthcare Materials, EarlyView.
Wound closure is governed by geometry‐orientation coupling: aligned fibers speed migration along their axis but hinder perpendicular advance. In vivo diabetic wound experiments with composition‐matched fibrin, combined with an anisotropic diffusion (biased random‐walk) model, quantify this trade‐off and generate a healing landscape.
Yin‐Yuan Huang, Xiangjun Peng, Yuxuan Huang, Kunkoo Kim, Chengli Li, Peilun Hu, Sean J. Wang, Rohan Avula, Chun‐Yi Yang, Pengchao Ma, Shuhui Yang, Shumeng Jiang, Guy M. Genin, Xiumei Wang   +13 more
wiley   +1 more source

Inhibition of Tendon Cell Proliferation and Matrix Glycosaminoglycan Synthesis by Non-Steroidal Anti-Inflammatory Drugs in vitro [PDF]

, 2002
The purpose of this study was to investigate the effects of some commonly used non-steroidal anti-inflammatory drugs (NSAIDs) on human tendon. Explants of human digital flexor and patella tendons were cultured in medium containing pharmacological ...
B. L HAZLEMAN, Brandt KD, Day RO, Dingle JT, Dingle JT, Flint M, G. P. RILEY, Gelberman RH, Hugenberg ST, M. COX, Martel-Pelletier J, Pelletier J-P, R. L. HARRALL, Rolf C, S. CLEMENTS, Scott JE, Thomas J   +16 more
core   +1 more source

Packed for Ossification: High‐Density Bioprinting of hPDC Spheroids in HAMA Toward Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
Human periosteum‐derived cell spheroids bioprinted at high density within a hyaluronic acid matrix promote fusion and hypertrophic cartilage formation in vitro. Early encapsulation enhances spheroid interaction and matrix maturation, generating scalable cartilage templates intended for endochondral bone regeneration.
Ane Albillos Sanchez, Maria Paula Marks, Paula Casademunt, Adrián Seijas‐Gamardo, Ioannis Papantoniou, Lorenzo Moroni, Carlos Mota   +6 more
wiley   +1 more source

Calculation of continuous reference intervals for biological parameters exhibiting strong age‐dependent level changes: Its application to glycosaminoglycans and sialic acid in urine

JIMD Reports
Glycosaminoglycan (GAG) and sialic acid (total and free) assays are used as first‐line screening tests for the diagnosis of mucopolysaccharidoses and glycoproteinoses, respectively.
Carlos Emilio Rodríguez, Mette Diswall, Anders Olsson, Torleif Jonsson, Eva Johansson, Maria Blomqvist   +5 more
doaj   +1 more source

The Physiological Mechanisms of Effect of Vitamins and Amino Acids on Tendon and Muscle Healing: A Systematic Review [PDF]

, 2018
© 2018 Human Kinetics, Inc.To evaluate the current literature via systematic review to ascertain whether amino acids/vitamins provide any influence on musculotendinous healing and if so, by which physiological mechanisms.
Abuja, Abuja, Akdemir, Akdemir, Anthony, Anthony, Anthony, Anthony, Anthony, Anthony, Anthony, Anthony, Arai, Arai, Barbul, Barbul, Blass, Blass, Bonci, Bonci, Bryant, Bryant, Buettner, Buettner, Cohen, Cohen, Collins, Collins, DerSimonian, DerSimonian, DiGuiseppi, DiGuiseppi, Dinçer, Dinçer, Ehrlich, Ehrlich, Ehrlich, Ehrlich, Eijnde, Eijnde, Ejaz, Ejaz, Galeano, Galeano, Gordon, Gordon, Gottrup, Gottrup, Greenwald, Greenwald, Gumina, Gumina, Hackam, Hackam, Hahn, Hahn, Henderson, Henderson, Hespel, Hespel, Hess, Hess, Higgins, Higgins, Hobson, Hobson, Holm, Holm, Hooijmans, Hooijmans, Hung, Hung, Hunt, Hunt, Judkins, Judkins, Kannus, Kannus, Kaplan, Kaplan, Kato, Kato, Kilkenny, Kilkenny, Kimball, Kimball, Kirk, Kirk, Knapik, Knapik, Knobloch, Knobloch, Li, Li, Li, Li, Lima, Lima, Malinauskas, Malinauskas, McDaniel, McDaniel, McGonigle, McGonigle, McHugh, McHugh, Moher, Moher, Moher, Moher, Molinero, Molinero, Mouw, Mouw, Negro, Negro, Norton, Norton, Notarnicola, Notarnicola, Otranto, Otranto, Pereira, Pereira, Pereira, Pereira, Petróczi, Petróczi, Petróczi, Petróczi, Petróczi, Petróczi, Popay, Popay, Raynaud-Simon, Raynaud-Simon, Reagan-Shaw, Reagan-Shaw, Rodgers, Rodgers, Rosa, Rosa, Sallis, Sallis, Sax, Sax, Schultz, Schultz, Sena, Sena, Sharp, Sharp, Shaw, Shaw, Shukla, Shukla, Stechmiller, Stechmiller, Stromberg, Stromberg, Sugaya, Sugaya, Svanberg, Svanberg, Tack, Tack, Tarnuzzer, Tarnuzzer, Tipton, Tipton, Torres-McGehee, Torres-McGehee, Tsilidis, Tsilidis, Uzgare, Uzgare, Vieira, Vieira, Vieira, Vieira, Viera, Viera, Virmani, Virmani, Wasserstein, Wasserstein, Watson, Watson, Wicke, Wicke, Williams, Williams, Woo, Woo, Yoshizawa, Yoshizawa, Ömeroğlu, Ömeroğlu   +197 more
core   +2 more sources

Purpose‐Adaptable Reinforced 3D Hyaluronic‐Acid Based Platform to Study Pathomechanisms of the Central Nervous System

Advanced Healthcare Materials, EarlyView.
Platform system to create biofabricated 3D spinal cord tissue models: Combining high resolution PCL fiber placement, a customized, hyaluronic acid‐based hydrogel, two cell types (spinal cord neurons and astrocytes) together with three distinct laminin isoforms allow the formation of functional cell–cell network interactions.
Nicoletta Murenu, Esra Tuerker, Anna‐Lena Wiessler, Jessica Faber, Ievgenii Liashenko, Jeanette Weigelt, Jörg Tessmar, Paul D. Dalton, Sibylle Jablonka, Mateo S. Andrade Mier, Carmen Villmann, Silvia Budday, Natascha Schaefer   +12 more
wiley   +1 more source

Arterial pathology in canine mucopolysaccharidosis-I and response to therapy. [PDF]

, 2011
Mucopolysaccharidosis-I (MPS-I) is an inherited deficiency of α-L-iduronidase (IdU) that causes lysosomal accumulation of glycosaminoglycans (GAG) in a variety of parenchymal cell types and connective tissues.
Dickson, Patricia I, Ellinwood, N Matthew, Kakkis, Emil D, Lyons, Jeremiah A, McEntee, Michael F, Passage, Merry B, Wall, Jonathan S   +6 more
core   +3 more sources