Results 71 to 80 of about 23,307 (259)

Herb5GluCon: A novel polyherbal formulation with dual-action inhibiting properties against oxidative stress and glycoside hydrolases – an in silico and in vitro approach

Phytomedicine Plus
Introduction: Oxidative stress contributes to hyperglycaemia by inducing the hyperactivity of alpha-amylase (AA) and alpha-glucosidase (AG) enzymes. The study aimed to evaluate the antioxidant and anti-glycoside hydrolase potential of a novel polyherbal ...
Abbirami Balachandran, Patrick N. Okechukwu, Baskaran Gunasekaran, Jeleń Małgorzata, Beata Morak-Młodawska, Gabriele R.A. Froemming, Sameer Sapra, Charlie A. Lavilla, Jr., Merell P. Billacura, Salini D. Rajendran, Anis Najwa Abdul Rani, Anand Gaurav   +11 more
doaj   +1 more source

Ecophysiology of Freshwater Verrucomicrobia Inferred from Metagenome-Assembled Genomes

mSphere, 2017
Microbes are critical in carbon and nutrient cycling in freshwater ecosystems. Members of the Verrucomicrobia are ubiquitous in such systems, and yet their roles and ecophysiology are not well understood.
Shaomei He, Sarah L. R. Stevens, Leong-Keat Chan, Stefan Bertilsson, Tijana Glavina del Rio, Susannah G. Tringe, Rex R. Malmstrom, Katherine D. McMahon   +7 more
doaj   +1 more source

Enzymatic Synthesis of Novel Vitexin Glucosides

Molecules, 2021
Vitexin is a C-glucoside flavone that exhibits a wide range of pharmaceutical activities. However, the poor solubility of vitexin limits its applications. To resolve this limitation, two glycoside hydrolases (GHs) and four glycosyltransferases (GTs) were
Jiumn-Yih Wu, Tzi-Yuan Wang, Hsiou-Yu Ding, Yun-Rong Zhang, Shu-Yuan Lin, Te-Sheng Chang   +5 more
doaj   +1 more source

Microbial ecological memory of recurrent drought enhances host stress tolerance through enrichment of plant‐beneficial bacteria

iMetaOmics, EarlyView.
Recurrent desiccation induced niche‐specific microbial ecological memory in the green part of Calohypnum plumiforme, marked by enrichment of plant‐beneficial bacteria, especially Methylobacterium and Sphingomonas, and functional shifts toward symbiosis and stress protection, potentially enhancing host tolerance within a “holobiont ecology memory ...
Chengguang Xing, Dandan Zhou, Dongwei Hou, Chunyi Lei, Zhiwei Liu, Jinhui Liu, Chaojian Hu, Jinye Liu, Shuzhen Huang, Yong Huo, Mingrui Zhou, Weiqiu Liu   +11 more
wiley   +1 more source

A Novel Glycoside Hydrolase DogH Utilizing Soluble Starch to Maltose Improve Osmotic Tolerance in Deinococcus radiodurans [PDF]

, 2023
Deinococcus radiodurans is a microorganism that can adjust, survive or thrive in hostile conditions and has been described as “the strongest microorganism in the world”.
Yuan Gui, Zhengfu Zhou, Jin Wang, Yongliang Yan, Min Lin, Shijie Jiang   +5 more
core   +1 more source

Transcriptomic analysis of Cryphonectria parasitica during the initial infection stages reveals a glycoside hydrolase that is required for fungal pathogenicity

Phytopathology Research
Chestnut blight, caused by Cryphonectria parasitica, is a notorious disease that severely harms chestnut species, leading to great economic and ecological loss worldwide. Understanding the pathogenic mechanisms of C.
Xiaolin Qiu, Can Huang, Dianguang Xiong, Lu Yu, Yuchen Yang, Xiaorong Lin, Chengming Tian   +6 more
doaj   +1 more source

Biocompatible Sulfobetaine Polymer‐Artemisinin Conjugates Inducing Ferroptosis in Cancer Cells: Synthesis by Mechanochemical Solid‐State Polymerization and Characterization

Macromolecular Rapid Communications, EarlyView.
The amphiphilic copolymer incorporating a hydrophobic chain conjugated with artesunate into a biocompatible sulfobetaine polymer is synthesized by solid‐state copolymerization of sulfobetaine methacrylate and methacrylamide derivative conjugating artesunate.
Naoki Doi, Yukinori Yamauchi, Yasushi Sasai, Ryosuke Nagai, Ayaka Koike, Madoka Ikawa, Toru Yoshimoto, Satoshi Yamada, Masayuki Kuzuya, Shin‐ichi Kondo   +9 more
wiley   +1 more source

VPI‐5482 glycoside hydrolase family 66 homolog catalyzes dextranolytic and cyclization reactions [PDF]

, 2012
Bacteroides thetaiotaomicron VPI-5482 harbors a gene encoding a putative cycloisomaltooligosaccharide glucanotransferase (BT3087) belonging to glycoside hydrolase family 66.
Young‐Min Kim, M S Kang, M Okuyama, Min‐Sun Kang, Mikihiko Kobayashi, Eiji Yamamoto, Mitsuru Momma, Masayuki Okuyama, M Kobayashi, Haruhide Mori, Kazumi Funane, W Saburi, H Mori, Z Fujimoto, Hiroyuki Nakai, K Funane, H Nakai, D Kim, M Momma, Wataru Saburi, Doman Kim, Zui Fujimoto, Young Min Kim, Atsuo Kimura, E Yamamoto, A Kimura   +25 more
core   +1 more source

Draft genome of pin nematode Paratylenchus projectus recovered from rhizosphere of blueberry

Parasites & Vectors
Background The pin nematode, belonging to the genus Paratylenchus, parasitizes higher plants, often causing reduced or inhibited root tip development. Methods Pin nematodes were isolated from the roots and rhizosphere of blueberry plants and subsequently
Liang-Qin Liu, Wei-Qi Fu, Yuan-Yuan Ma, Zhi-Yin Liu, Chun-feng Ge, Yi-Ru Yang, Xue Qing, Qi-Long Zeng   +7 more
doaj   +1 more source

Redefining CHI3L1: Therapeutic Opportunities at the Crossroads of Immune Suppression and Disease Progression

Medicinal Research Reviews, EarlyView.
ABSTRACT Chitinase‐3‐like‐1 (CHI3L1, also known as YKL‐40) has been recognized as a biomarker of inflammation and tissue remodeling and has now emerged as a pseudoenzymatic immune checkpoint. Recent structural, immunological, and translational studies redefine it as an active regulator of immune suppression rather than a passive disease marker. Despite
Kirti Upmanyu, Saurabh Upadhyay, Moustafa T. Gabr   +2 more
wiley   +1 more source