Safety Evaluation of an Aqueous Root and Leaf Extract of Ashwagandha (Withania somnifera)
Sensoril, an aqueous root and leaf extract of ashwagandha showed no evidence of mutagenicity in the in vitro Ames assay, was negative in the in vitro micronucleus, in vivo mammalian bone marrow chromosome aberration assays, and was well tolerated in the rat at up to 4000 mg/kg BW/day when administered orally for a period of 90 days. The data from these
Mukesh Summan +2 more
wiley +1 more source
Promiscuous Transferases Malonylate Furaneol Glucoside in <i>Fragaria</i> × <i>ananassa</i>. [PDF]
Wulanjati MP +4 more
europepmc +1 more source
Phytochemicals in MASLD: A Focused Review of Gut Microbiome‐Linked Mechanisms
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as a major global health burden, yet effective pharmacological options remain limited. Recent advances highlight the gut microbiome as a key modulator of liver metabolism, inflammation, and fibrosis, making it a promising therapeutic target.
Jeong In Seo, Su Min Kim, Hye Hyun Yoo
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Synthesis, Biological Evaluation, and Computational Studies of Phenolic <i>N</i>-Acetylglucosamine Glycosides as α-Glucosidase Inhibitors. [PDF]
Wang W +7 more
europepmc +1 more source
Emulsion type governed the microstructure and functionality of papers coated with biopolymers matrix loaded with hydrophobic bioactives encapsulated into O/W emulsions. Emulsified systems improved UV–Vis barrier and antioxidant activity, whereas gelatin coatings with conventional or Pickering emulsions provided the greatest mechanical reinforcement ...
Kamila de L. Santos +4 more
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When herbal supplements cause heart problems: Clinical case report and forensic toxicological analysis. [PDF]
Theuer T +9 more
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ABSTRACT This study evaluated the water quality of artesian wells and effluents generated in cassava processing in a rural area of Bragança, Pará, with emphasis on physicochemical parameters, multielement composition, and cyanogenic compounds. The well water presented specific nonconformities, highlighting pH values below the recommended level and high
Alana Coêlho Maciel +13 more
wiley +1 more source
Safety and efficacy of a feed additive consisting of a proanthocyanidin-rich dry extract from the fruit of <i>Vaccinium macrocarpon</i> Aiton (cranberry extract) for dogs and cats (ACEL pharma S.r.l.). [PDF]
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +26 more
europepmc +1 more source
Read the free Plain Language Summary for this article on the Journal blog. Abstract Root exudates play a key role as signals and nutrients in mediating plant–microbe communication. However, critical knowledge gaps remain regarding how root exudates mediate soil–microbe–plant interactions to regulate crop yield under long‐term straw mulching combined ...
Jiajie Song +7 more
wiley +1 more source
Antibodies as Tools for Characterization, Isolation and Production Enhancement of Anti-Cancer Drugs and Steroidal Hormones from Ginsenoside and Solasodine Glycoside: A Review. [PDF]
Shoyama Y.
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