Results 31 to 40 of about 280,308 (388)

Emerging organometallic methods for the synthesis of C-branched (hetero)aryl, alkenyl and alkyl glycosides: C-H functionalization and dual photoredox approaches.

Chemistry, 2020
Transition-metal catalyzed C-H functionalization and photoredox-nickel dual catalysis have emerged as innovative and powerful avenues for the synthesis of C -branched glycosides. These two concepts have been recently established and provide efficient and
Juba Ghouilem, Morgane Robichon, Franck Le Bideau, A. Ferry, S. Messaoudi   +4 more
semanticscholar   +1 more source

Exploring and applying the substrate promiscuity of a C-glycosyltransferase in the chemo-enzymatic synthesis of bioactive C-glycosides

Nature Communications, 2020
Bioactive natural C-glycosides are rare and chemical C-glycosylation faces challenges while enzymatic C-glycosylation catalyzed by C-glycosyltransferases provides an alternative way. However, only a small number of C-glycosyltransferases have been found,
Kebo Xie, Xiao-lin Zhang, Song-yang Sui, Fei Ye, J. Dai   +4 more
semanticscholar   +1 more source

Angling for Uniqueness in Enzymatic Preparation of Glycosides

Biomolecules, 2013
In the early days of biocatalysis, limitations of an enzyme modeled the enzymatic applications; nowadays the enzyme can be engineered to be suitable for the process requirements.
Antonio Trincone
doaj   +1 more source

Toxic Phenolic Glycosides From \u3ci\u3ePopulus:\u3c/i\u3e Physiological Adaptations of the Western North American Tiger Swallowtail Butterfly, \u3ci\u3ePapilio Rutulus\u3c/i\u3e (Lepidoptera: Papilionidae) [PDF]

, 2017
The phenolic glycosides tremulacin and salicortin found in quaking aspen, Populus tremuloides, and other members of the Salicaceae, are known to be toxic to larvae of the Eastern tiger swallowtail butterfly, Papilio glaucus, but not to the Canadian tiger
Lindroth, Richard L, Nitao, James K, Scriber, J. Mark   +2 more
core   +2 more sources

Anomeric O-Functionalization of Carbohydrates for Chemical Conjugation to Vaccine Constructs

Molecules, 2018
Carbohydrates mediate a wide range of biological interactions, and understanding these processes benefits the development of new therapeutics. Isolating sufficient quantities of glycoconjugates from biological samples remains a significant challenge ...
Simon S. Park, Hsiao-Wu Hsieh, Jacquelyn Gervay-Hague   +2 more
doaj   +1 more source

Novel 1,2,3-Triazole-Coumarin Hybrid Glycosides and Their Tetrazolyl Analogues: Design, Anticancer Evaluation and Molecular Docking Targeting EGFR, VEGFR-2 and CDK-2

Molecules, 2022
This study represents the design and synthesis of a new set of triazole-coumarin-glycosyl hybrids and their tetrazole hybrid analogues possessing various sugar moieties and modified analogues. All the newly synthesized derivatives were screened for their
Wael A. El-Sayed, Fahad M. Alminderej, Marwa M. Mounier, Eman S. Nossier, Sayed M. Saleh, Asmaa F. Kassem   +5 more
doaj   +1 more source

Predicting the substrate specificity of a glycosyltransferase implicated in the production of phenolic volatiles in tomato fruit [PDF]

, 2011
The volatile compounds that constitute the fruit aroma of ripe tomato (Solanum lycopersicum) are often sequestered in glycosylated form. A homology-based screen was used to identify the gene SlUGT5, which is a member of UDP-glycosyltransferase 72 family ...
Alba, Baldwin, Birtic, Bowles, Brazier-Hicks, Brazier-Hicks, Brazier-Hicks, Buttery, Chervin, Fleuriet, Fukuchi-Mizutani, Gachon, Hansen, Hefner, Jones, Jones, Jugdé, Kino, Lairson, Lairson, Lanot, Lanot, Li, Lim, Loutre, Lunkenbein, Marlatt, Morris, Ortiz-Serrano, Pang, Ross, Sali, Schuettelkopf, Shimoda, Smart, Song, Syahrani, Tikunov, Wang, Witte, Yoon, Zanor   +41 more
core   +2 more sources

Antitumor, antioxidant and anti-inflammatory activities of kaempferol and its corresponding glycosides and the enzymatic preparation of kaempferol

PLoS ONE, 2018
Kaempferol (kae) and its glycosides are widely distributed in nature and show multiple bioactivities, yet few reports have compared them. In this paper, we report the antitumor, antioxidant and anti-inflammatory activity differences of kae, kae-7-O ...
Jingqiu Wang, Xianying Fang, Lin Ge, F. Cao, Linguo Zhao, Zhenzhong Wang, W. Xiao   +6 more
semanticscholar   +1 more source

Potential Therapeutic Anti-Inflammatory and Immunomodulatory Effects of Dihydroflavones, Flavones, and Flavonols

Molecules, 2020
Systemic inflammation, circulating immune cell activation, and endothelial cell damage play a critical role in vascular pathogenesis. Flavonoids have shown anti-inflammatory effects.
Cristina Zaragozá, Lucinda Villaescusa, Jorge Monserrat, Francisco Zaragozá, Melchor Álvarez-Mon   +4 more
doaj   +1 more source

A gene-derived SNP-based high resolution linkage map of carrot including the location of QTL conditioning root and leaf anthocyanin pigmentation [PDF]

, 2014
Purple carrots accumulate large quantities of anthocyanins in their roots and leaves. These flavonoid pigments possess antioxidant activity and are implicated in providing health benefits.
Cavagnaro, Pablo Federico, Ellison, Shelby, Iorizzo, Massimo, Parsons, Joshua, Senalik, Douglas, Simon, Philipp W., Yildiz, Mehtap   +6 more
core   +2 more sources