Results 71 to 80 of about 159,503 (303)

Molecular phenotyping of the pal1 and pal2 mutants of Arabidopsis thaliana reveals far-reaching consequences on phenylpropanoid, amino acid, and carbohydrate metabolism [PDF]

, 2004
The first enzyme of the phenylpropanoid pathway, Phe ammonia-lyase (PAL), is encoded by four genes in Arabidopsis thaliana. Whereas PAL function is well established in various plants, an insight into the functional significance of individual gene family ...
Boerjan, Wout, De Rycke, Riet, Goeminne, Geert, Hostyn, Vanessa, Joseleau, Jean-Paul, Kushnir, Sergei, Messens, Eric, Morreel, Kris, Ralph, John, Rohde, Antje, Van Beeumen, Jozef, Van Doorsselaere, Jan, Van Driessche, Gonzalez, Vuylsteke, Marnik   +13 more
core   +3 more sources

Preparation, Component Identification, and Antioxidant Activity of Anthocyanins From Punica granatum “Tunisia”

AgriFood: Journal of Agricultural Products for Food, EarlyView.
The preparation for Tunisian pomegranate anthocyanin extract. The molecular mechanisms underlying the antioxidant effects of these compounds were investigated using network pharmacology and molecular docking. Antioxidant activity was evaluated through DPPH, ABTS, and FRAP assays, whereas the effects on oxidative stress and inflammation were examined in
Jing Zhang, Xu‐han Yang, Meng‐qi Zhang, Xu Guo, Ning‐yang Li, Fang‐yu Long, Chao Liu   +6 more
wiley   +1 more source

Click chemistry based synthesis, cytotoxic activity and molecular docking of novel triazole-thienopyrimidine hybrid glycosides targeting EGFR

Journal of Enzyme Inhibition and Medicinal Chemistry, 2021
In the current study, new thienopyrimidine conjugates bearing 1,2,3-triazole core and different sugar moieties have been designed and synthesized by Cu(I)-catalysed click dipolar cycloaddition. The cytotoxic activity of the synthesised conjugates 2, 5, 7,
Reham R. Khattab, Asma K. Alshamari, Allam A. Hassan, Hussein H. Elganzory, Wael A. El-Sayed, Hanem M. Awad, Eman S. Nossier, Nasser A. Hassan   +7 more
doaj   +1 more source

One-pot multicomponent synthesis of 2,3-dihydropyrans: new access to furanose–pyranose 1,3-C–C-linked-disaccharides [PDF]

, 2009
An efficient synthesis of 2,3-dihydropyrans starting from different terminal alkynes was developed. The 2,3-dihydropyrans were obtained in a few minutes through a microwave-assisted multicomponent enyne cross-metathesis/hetero-Diels–Alder reaction ...
Armstrong, Bataille, Beccalli, Bertozzi, Boivin, Castagnolo, Castagnolo, Class, Coppi, Daniele Castagnolo, Dondoni, Dondoni, Giessert, Guerrini, Haraguchi, Li, Liu, Lorenzo Botta, Maurizio Botta, Nair, Nicolaou, Oishi, Ramon, Schmidt, Strecker, Strubing, Tietze, Tietze, Yet   +28 more
core   +1 more source

A seed-specific regulator of triterpene saponin biosynthesis in Medicago truncatula [PDF]

, 2020
Plants produce a vast array of defense compounds to protect themselves from pathogen attack or herbivore predation. Saponins are a specific class of defense compounds comprising bioactive glycosides with a steroidal or triterpenoid aglycone backbone. The
Arendt, Philipp, Bicalho, Keylla, Buitink, Julia, Calegario, Gabriela, Ceulemans, Evi, Goossens, Alain, Gryffroy, Lore, Lacchini, Elia, Mertens, Jan, Pollier, Jacob, Ribeiro, Bianca, Vanden Bossche, Robin   +11 more
core   +2 more sources

Fermented Citrus as a Functional Food Matrix: Evaluating Probiotic, Prebiotic, and Postbiotic Potential

AgriFood: Journal of Agricultural Products for Food, EarlyView.
Fermented citrus transforms bioactive compounds into metabolites with probiotic and prebiotic properties, enhancing gut health, immunity, and metabolic balance. This review highlights fermentation's role in developing sustainable, health‐promoting functional foods while addressing challenges in process optimization, sensory quality, and commercial ...
Sony Kumari, Rahel Debbarma, Shakil Haque, Himalay Baruah   +3 more
wiley   +1 more source

Large‐Scale Machine Learning to Screen for Small‐Molecule Senolytics

Advanced Intelligent Discovery, EarlyView.
A consistent workflow underpins all experiments in this study. A dedicated model‐selection dataset first identifies optimal hyperparameters for each algorithm. Models are then trained and rigorously evaluated on independent sets of molecules using the senolytic ratio SR. Comprehensive hyperparameter exploration across SMILES representations, task types,
Alexis Dougha, Jesus Gil, Pedro J. Ballester   +2 more
wiley   +1 more source

Strategies toward protecting group-free glycosylation through selective activation of the anomeric center

Beilstein Journal of Organic Chemistry, 2017
Glycosylation is an immensely important biological process and one that is highly controlled and very efficient in nature. However, in a chemical laboratory the process is much more challenging and usually requires the extensive use of protecting groups ...
A. Michael Downey, Michal Hocek
doaj   +1 more source

Aroma potential of three autochthonous grapevine varieties from Tunisia

OENO One, 2008
Aims: The aim of the present work is to characterize the aromatic profiles of three Tunisian autochthonous grapevine (Vitis vinifera L.) varieties (Asli, Beldi and Ferrani). Methods and results: The GC-MS analysis of the autochthonous grapevine varieties
Imène Souid, Zemni Hassene, Eva Sánchez Palomo, Maria Soledad Pérez-Coello, Abdelwahed Ghorbel   +4 more
doaj   +1 more source

Safety in use of glucosylated steviol glycosides as a food additive in different food categories [PDF]

, 2018
The EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS) provides a scientific opinion on the safety of glucosylated steviol glycosides proposed for use as a new food additive in different food categories.
Agneta Oskarsson, Alicja Mortensen, Ana Maria Rincon, Birgit Dusemund, Camilla Smeraldi, Claude Lambré, David Gott, Fernando Aguilar, Gunter Georg Kuhnle, Ine Waalkens‐Berendsen, Inger Therese Lillegaard, Ivan Stankovic, Jean‐Charles Leblanc, Maged Younes, Maria Jose Frutos, Matthew Wright, Metka Filipič, null null, Paul Tobback, Peter Aggett, Peter Moldeus, Pierre Galtier, Riccardo Crebelli, Rudolf Antonius Woutersen, Ursula Gundert‐Remy   +24 more
core   +1 more source