Results 71 to 80 of about 199,203 (353)
The preparation for Tunisian pomegranate anthocyanin extract. The molecular mechanisms underlying the antioxidant effects of these compounds were investigated using network pharmacology and molecular docking. Antioxidant activity was evaluated through DPPH, ABTS, and FRAP assays, whereas the effects on oxidative stress and inflammation were examined in
Jing Zhang +6 more
wiley +1 more source
2-Deoxy-2-iodo- and 2-deoxy-2-bromoglucopyranosyl trichloroacetimidates 8−10 and 22 are extremely useful precursors of 2-deoxy-β-glycosides. These reactive glycosyl donors undergo highly stereoselective glycosidation reactions at −78 °C with a range of ...
Benjamin W. Gung (2277694) +2 more
core +1 more source
Steviol glycosides (SGs), such as stevioside and rebaudioside A, are natural, non-caloric sweet-tasting organic molecules, present in extracts of the scrub plant Stevia rebaudiana, which are widely used as sweeteners in consumer foods and beverages ...
Koenraad Philippaert +20 more
semanticscholar +1 more source
Fermented citrus transforms bioactive compounds into metabolites with probiotic and prebiotic properties, enhancing gut health, immunity, and metabolic balance. This review highlights fermentation's role in developing sustainable, health‐promoting functional foods while addressing challenges in process optimization, sensory quality, and commercial ...
Sony Kumari +3 more
wiley +1 more source
Large‐Scale Machine Learning to Screen for Small‐Molecule Senolytics
A consistent workflow underpins all experiments in this study. A dedicated model‐selection dataset first identifies optimal hyperparameters for each algorithm. Models are then trained and rigorously evaluated on independent sets of molecules using the senolytic ratio SR. Comprehensive hyperparameter exploration across SMILES representations, task types,
Alexis Dougha +2 more
wiley +1 more source
Marine Microalgae Biomolecules and Their Adhesion Capacity to Salmonella enterica sv. Typhimurium
Different molecules have been tested as analog receptors due to their capacity to bind bacteria and prevent cell adhesion. By using in vitro assays, the present study characterized the aqueous and alkaline extracts from microalgae Pavlova lutheri and ...
Tatiane Winkler Marques Machado +4 more
doaj +1 more source
Three new chlorinated phenolic glycosides from Przewalskia tangutica
Three new chlorinated phenolic glycosides, namely przewatangosides A-C (1-3), along with one known compound, globosumoside A (4), were isolated from the whole plants of Przewalskia tangutica.
Gu, YC +8 more
core +1 more source
Synthesis of Reversed C-Acyl Glycosides via Ni/Photoredox Dual Catalysis
The incorporation of C-glycosides in drug design has become a routine practice for medicinal chemists. These naturally occurring building blocks exhibit attractive pharmaceutical profiles, becoming an extensive topic of synthetic efforts in recent ...
Shorouk O. Badir +3 more
semanticscholar +1 more source
Angling for Uniqueness in Enzymatic Preparation of Glycosides
In the early days of biocatalysis, limitations of an enzyme modeled the enzymatic applications; nowadays the enzyme can be engineered to be suitable for the process requirements.
Antonio Trincone
doaj +1 more source
Anomeric O-Functionalization of Carbohydrates for Chemical Conjugation to Vaccine Constructs
Carbohydrates mediate a wide range of biological interactions, and understanding these processes benefits the development of new therapeutics. Isolating sufficient quantities of glycoconjugates from biological samples remains a significant challenge ...
Simon S. Park +2 more
doaj +1 more source

