Results 151 to 160 of about 252,043 (349)

Hidden O‐Deglycosylation Activity Triggers O → C Rearrangement for Aryl Di‐C‐Glucoside Formation by the C‐Glycosyltransferase From Fortunella crassifolia

Biotechnology and Bioengineering, EarlyView.
Here, we uncovered an unexpected O‐deglycosylation activity of the C glycosyltransferase (FcCGT), forming phloretin (1) from phloretin 2'‐O‐glucoside (2). In the presence of UDP, FcCGT catalyzes the O→C rearrangement to yield nothofagin (3). Upon additional UDP‐glucose, further C‐glycosylation occurs, forming phloretin 3',5'‐di‐C‐glucoside (4 ...
Tuo Li, Annika J. E. Borg, Leo Krammer, Rolf Breinbauer, Bernd Nidetzky   +4 more
wiley   +1 more source

Peer review report 2 on “Association between elevated pre-operative glycosylated hemoglobin and post-operative infections after non-emergent surgery”

, 2016
Andrea Conforti
openalex   +1 more source

RBD‐SD1 Nanoparticle Vaccines From DPP4‐Using Merbecoviruses Elicit a Cross‐Reactive Antibody Response but Limited Cross‐Protective Immunity

Biotechnology and Bioengineering, EarlyView.
SpyCatcher‐mi3 nanoparticles displaying RBD‐SD1 from MERS‐CoV, NL140422, and HKU4 elicited robust and cross‐reactive IgG responses in mice. Only MERS‐CoV RBD‐SD1 induced neutralizing antibodies against MERS‐CoV and protected human DPP4 mice from a MERS‐CoV challenge, indicating conserved serologic but limited cross‐neutralizing epitopes.
Peter J. Halfmann, Jeong Soo Lee, Tong Wang, Augustine Duffy, Janie E. Rogers, Natasha Chen, Elizabeth Frimpong, Carmen Rai, Yoshihiro Kawaoka, Ravi S. Kane   +9 more
wiley   +1 more source

OCT ASSESSMENT OF MACULAR THICKNESS IN NON-PROLIFERATIVE DIABETIC RETINOPATHY IN RELATION TO GLYCOSYLATED HEMOGLOBIN [PDF]

, 2021
Amr Muhammad Badr Salah El-Deen, Hazem Mohamed Sammor, Mohammed Al Taher Abd El-Wahab   +2 more
openalex   +1 more source

Engineered Bacterial Ligand From Streptococcus pneumoniae on Macroporous Resins for Selective Affinity Capture of Secretory IgA

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Secretory immunoglobulin A (sIgA) is a promising emerging biopharmaceutical candidate, but it currently lacks a standardized platform for purification. To address this, a novel affinity chromatography resin was developed by immobilizing protein variants of the Streptococcus pneumoniae surface protein, SpsA, as an affinity ligand.
David Scheich, Andres Männik, Oliver Meikar, Joan Teyra, Laura Kibena, Sebastiaan Eeltink, Rainer Hahn, Alois Jungbauer, Nico Lingg   +8 more
wiley   +1 more source

Reviewer #1 (Public Review): Allosteric modulation by the fatty acid site in the glycosylated SARS-CoV-2 spike

A Sofia F Oliveira, Fiona L Kearns, Mia A Rosenfeld, Lorenzo Casalino, Imre Berger, Christiane Schaffitzel, Andrew D Davidson, Rommie E Amaro, Adrian J Mulholland   +8 more
openalex   +2 more sources

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source

A Study of Correlation of Serum Chromium Level with Glycosylated Haemoglobin (HbA1c), Total Cholesterol and Triglycerides, among Type 2 Diabetes Patients

, 2019
Hani M. Mohamed, Isam M. Sadik, Abdelgadir Elamin Eltom, Ahmed L. Osman, Asaad Babker   +4 more
openalex   +2 more sources

Mimic, target, and adapt: Cell membrane‐coated nanoplatforms for precision and immune‐guided cancer treatment

BMEMat, EarlyView.
This Perspective explores the emerging landscape of cell membrane‐coated nanoparticles (CM‐NPs) as intelligent, immune‐compatible platforms for cancer therapy. Highlighting design strategies, translational challenges, and competitive positioning, it outlines how integrating biomimetic targeting with advanced analytical and manufacturing tools could ...
A. K. M. M. Alam, Xiaojun Cai, Malik Ihsan Ullah Khan, Robert Musiol, Quazi T. H. Shubhra   +4 more
wiley   +1 more source

Synthesis and Glycosidase Inhibition Studies of Novel Exoglycals Targeting GH3 Family Enzymes: Insights from Comparative Analysis with Macrolide Antibiotics

Chemistry – A European Journal, EarlyView.
A series of structurally diverse exoglycals was synthesized using a modified Julia‐olefination approach from sugar‐derived precursors. These glycosidase transition‐state mimics were further diversified via CuAAC chemistry to yield triazole‐conjugated analogues.
Elisa Ospanow, Oscar L. Alferez, David L. Jakeman   +2 more
wiley   +1 more source