Results 161 to 170 of about 252,043 (349)

Macrotermycins A–D, Glycosylated Macrolactams from a Termite-Associated Amycolatopsis sp. M39

, 2017
Christine Beemelmanns, Timothy R. Ramadhar, Ki Hyun Kim, Jonathan L. Klassen, Shugeng Cao, Thomas P. Wyche, Yanpeng Hou, Michael Poulsen, Tim S. Bugni, Cameron R. Currie, Jon Clardy   +10 more
openalex   +2 more sources

Data from Novel Glycosylated VEGF Decoy Receptor Fusion Protein, VEGF-Grab, Efficiently Suppresses Tumor Angiogenesis and Progression

, 2023
Jung‐Eun Lee, Chan Kim, Hannah Yang, Intae Park, Nuri Oh, Serenus Hua, Ha-Neul Jeong, Hyun Joo An, Sun Chang Kim, Gyun Min Lee, Gou Young Koh, Ho Min Kim   +11 more
openalex   +1 more source

Bioresponsive pseudoGlucosinolates (psGSLs) Release Isothiocyanates (ITCs) in the Presence of Nitroreductases

Chemistry – A European Journal, EarlyView.
This work introduces the concept of pseudoglucosinolates (psGSLs) and reports the synthesis and evaluation of nitroreductase‐responsive psGSLs. These compounds represent a complementary prodrug strategy to natural glucosinolates (GSLs) for the controlled release of isothiocyanates (ITCs), enabling bio‐responsive protein labeling, as demonstrated in ...
Claire C. Jimidar, Charity S. G. Ganskow, Mervic D. Kagho, Aishi Chakrabarti, Lorenz Wiese, Michael Zollo, Ulrike Beutling, Leona C. Cesar, Julia Morud, Kamila Bugaj, Mark Brönstrup, Stephan A. Sieber, Stephan M. Hacker, Philipp Klahn   +13 more
wiley   +1 more source

Synthesis of Potential Glycosylated Anticancer Compounds

, 2018
Amy Au
openalex   +1 more source

Synthesis and Biological Evaluation of Well‐Defined M6P(n)‐Modified Glycopeptides for Targeted Protein Degradation

Chemistry – A European Journal, EarlyView.
A synthetic methodology has been developed to prepare multifunctional M6P and M6Pn ligands of different valency. The glycopeptides were conjugated to cetuximab and then examined to mediate cellular uptake of fluorescently labeled EGFRvIII. Only cetuximab modified by glycopeptides having 3 or 6 M6P or M6Pn residues demonstrated greater uptake.
Patrycja Lenartowicz, Jan‐Willem H. Langenbach, Nataliia Voloshyna, David Aidukas, Arwin J. Brouwer, John A. W. Kruijtzer, Geert‐Jan Boons   +6 more
wiley   +1 more source

Immunodetection of partially glycosylated isoforms of α‐dystroglycan by a new monoclonal antibody against its β‐dystroglycan‐binding epitope [PDF]

, 2004
Ernesto Pavoni, Francesca Sciandra, Stefano Barca, Bruno Giardina, Tamara C. Petrucci, Andrea Brancaccio   +5 more
openalex   +1 more source

Recombinant Monoclonal Antibodies for Detecting the Tubulin Post‐Translational Modifications Glutamylation and Lysine‐40 Acetylation

Cytoskeleton, EarlyView.
ABSTRACT Post‐translational modifications (PTMs) to tubulin subunits in microtubule filaments are thought to comprise a component of the tubulin code that specifies microtubule functions in cell physiology and animal development. Acetylation of Lysine‐40 (K40) on α‐tubulin (αTub‐K40ac) and glutamylation of both α‐ and β‐tubulin are two tubulin PTMs of ...
Lynne Blasius, Ezekiel C. Thomas, Erik H. Collet, Erin Jenson, Chad G. Pearson, Ryoma Ohi, Kristen J. Verhey   +6 more
wiley   +1 more source

A Glycosylated RBD Protein Induces Enhanced Neutralizing Antibodies against Omicron and Other Variants with Improved Protection against SARS-CoV-2 Infection

, 2022
Juan Shi, Jian Zheng, Wanbo Tai, Abhishek Kumar Verma, Xiujuan Zhang, Qibin Geng, Gang Wang, Xiao‐Qing Guan, Moffat M. Malisheni, Abby Odle, Wei Zhang, Fang Li, Stanley Perlman, Lanying Du   +13 more
openalex   +2 more sources

Detection of the GH Analogue Redalsomatropin Alfa in Sports Drug Testing: Immunological Approaches and LC‐HRMS/MS

Drug Testing and Analysis, EarlyView.
After evaluating the compatibility of the GH analogue redalsomatropin alfa with approved doping control immunoassays for rhGH, it was implemented into the existing detection method for somatrogon employing affinity purification with GHR‐Fc‐conjugated magnetic beads, tryptic digestion, and LC‐HRMS/MS to allow for a specific and sensitive detection ...
Katja Walpurgis, Andreas Thomas, Jasmin Thelen, Bettina Majer, Maneera Al‐Jaber, Wadha Abushareeda, Mario Thevis   +6 more
wiley   +1 more source

Glycosylated Hemoglobin: A Tool in Identifying Psychological Problems? [PDF]

, 1980
Wendy Citrin, George J. Ellis, Jay S. Skyler   +2 more
openalex   +1 more source