Results 191 to 200 of about 347,689 (338)

Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy

BMEMat, EarlyView.
This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma, Songyan Li, Jie Yan, Xuechun Wang, Wen Zhao, Yunxuan Song, Dongdong Liu, Jianwei Jiao, Xiuying Duan, Guiqiang Zhang   +9 more
wiley   +1 more source

Endothelial glycosylation and its emerging role in pulmonary vascular health and disease. [PDF]

Nat Commun
Nazaire V, Chandler KB.
europepmc   +1 more source

Wnt-driven O-glycosylation by LARGE2 in human colon and colorectal cancer [PDF]

, 2020
Vanessa Dietinger
openalex   +1 more source

Scale‐up of a monoclonal antibody CHO fed‐batch production in stirred tank bioreactors: Effect of hydrodynamic conditions and feeding regimen

Biotechnology Progress, EarlyView.
Abstract Key hydrodynamic‐related parameters such as volumetric power input (P/V), impeller configuration, aeration strategy, and maximum gas sparge rate, as well as an appropriate feeding strategy, must be carefully selected to improve production yields in bioreactor.
Lucas Lemire, Sebastian‐Juan Reyes, Yves Durocher, Robert Voyer, Olivier Henry, Phuong Lan Pham   +5 more
wiley   +1 more source

Comparative glycomic analysis of Mimiviridae and Marseilleviridae uncovers host-related and lineage-specific glycosylation. [PDF]

J Biochem
Shim J, Hozumi C, Kurogochi M, Yagi-Utsumi M, Furukawa JI, Takemura M, Yagi H, Kato K.   +7 more
europepmc   +1 more source

Plasma Membrane Targeting of Endogenous NKCC2 in COS7 Cells Bypasses Functional Golgi Cisternae and Complex N-Glycosylation [PDF]

, 2017
Richa Singh, Shams Kursan, Mohamed Y. Almiahoub, Mohammed M. Almutairi, Tomás Garzón-Muvdi, Francisco J. Alvarez‐Leefmans, Mauricio Di Fulvio   +6 more
openalex   +1 more source

Dynamic pH profiles drive higher cell‐specific and volumetric productivity

Biotechnology Progress, EarlyView.
Implementation of dyamic pH profiles for increased CHO cell culture productivity. Abstract Mammalian cell cultures in bioreactors rely heavily on critical process parameter control to ensure optimal growth, productivity, and reproducibility to produce recombinant therapeutic proteins. Culture pH has been shown to be a critical parameter that influences
Stephanie R. Klaubert, Dylan G. Chitwood, Danqia Peng, Erin Redman, Ji Young L. Anderson, Nicholas R. Sandoval, Sarah W. Harcum   +6 more
wiley   +1 more source

Does Altered Membrane Glycosylation Contribute to Neurodevelopmental Dysfunction in Autism Spectrum Disorder? [PDF]

Membranes (Basel)
Osterne VJS, Oliveira MV, Pinto-Junior VR, Mota FSB, Cavada BS, Nascimento KS.   +5 more
europepmc   +1 more source

Overexpression of N-acetylglucosaminyltransferases III and V in human melanoma cells. Implications for MCAM N-glycosylation

, 2014
Monika Bubka, Paweł Link‐Lenczowski, Marcelina Janik, Ewa Pocheć, Anna Lityń́ska   +4 more
openalex   +2 more sources

Artificial intelligence and machine learning‐assisted digital applications for biopharmaceutical manufacturing

Biotechnology Progress, EarlyView.
Abstract Artificial intelligence and automation are no longer just buzzwords in the biopharmaceutical industry. The manufacturing of a class of biologics, comprising monoclonal antibodies, cell therapies, and gene therapies, is far more complex than that of traditional small molecule drugs.
Shyam Panjwani, Hao Wei, John Mason
wiley   +1 more source