Deglycosylation and truncation in the neuraminidase stalk are functionally equivalent in enhancing the pathogenicity of a high pathogenicity avian influenza virus in chickens. [PDF]
Kobayashi D+8 more
europepmc +1 more source
Discovery, design, and engineering of enzymes based on molecular retrobiosynthesis
Abstract Biosynthesis—a process utilizing biological systems to synthesize chemical compounds—has emerged as a revolutionary solution to 21st‐century challenges due to its environmental sustainability, scalability, and high stereoselectivity and regioselectivity.
Ancheng Chen+5 more
wiley +1 more source
Overexpression of Tn antigen induces chronic pancreatitis in mice. [PDF]
Mercanoglu B+9 more
europepmc +1 more source
The Antiviral Activity of Polyphenols
Polyphenols demonstrate remarkable antiviral properties by effectively disrupting multiple biochemical processes essential for viral replication. ABSTRACT Polyphenols are secondary metabolites produced by a large variety of plants. These compounds that comprise the class of phenolic acids, stilbenes, lignans, coumarins, flavonoids, and tannins have a ...
Markus Burkard+5 more
wiley +1 more source
Plasma N-Glycoproteomics in monozygotic twin pairs discordant for body mass index reveals an obesity signature related to inflammation and iron metabolism. [PDF]
Muniandy M+13 more
europepmc +1 more source
Effect of Natural Polyphenols on Breast Cancer Chemoprevention and Treatment
Effect of Natural Polyphenols on Breast Cancer proliferation and progression. ABSTRACT Breast cancer is the most common type of malignancy among women worldwide. Significant achievements have been made in diagnostic tools and cancer treatments in the past decade; however, the complexity and heterogeneity of certain breast cancer subtypes often lead to ...
Marzia Sichetti+4 more
wiley +1 more source
Nitrene-mediated glycosylation with thioglycoside donors under metal catalysis. [PDF]
Bai Z+5 more
europepmc +1 more source
Understanding how foods and enteral feedings influence the gut microbiome
Abstract The gut microbiome supports both gut and overall health. Diet is known to be one of the driving factors that influences the gut microbiome. The foods we eat, the dietary and nondietary components they contain, various food consumption patterns, and the ratio of nutrients consumed have been shown to impact gut microbiome composition and ...
Gail A. M. Cresci
wiley +1 more source
Poly-sialylated glycan of cervicovaginal fluid can be a potential marker of preterm birth. [PDF]
Go YY+8 more
europepmc +1 more source