Results 71 to 80 of about 2,358 (202)

Modulation of innate immune responses at birth by prenatal malaria exposure and association with malaria risk during the first year of life. [PDF]

, 2018
BACKGROUND: Factors driving inter-individual differences in immune responses upon different types of prenatal malaria exposure (PME) and subsequent risk of malaria in infancy remain poorly understood.
A Berg, A Dent, A Iwasaki, A Le Port, A Rachas, A Sarangi, AA Adegnika, AEP Frosch, AH Omar, AJF Luty, Anna Rosanas-Urgell, B Mbengue, B Sylvester, BA Blok, C Coban, Carlota Dobaño, CL King, CS Boutlis, D Prakash, E Kabyemela, EB Brickley, EB Staros, Eduard Rovira-Vallbona, EM Eriksson, G Moncunill, G Reed, G Xi, Gemma Moncunill, H Sanz, Halidou Tinto, Hamtandi Magloire Natama, HB Armah, Henk D. F. H. Schallig, Hermann Sorgho, HM Natama, HM Natama, HM Natama, Héctor Sanz, I Angulo, I Engelmann, I Malhotra, I Malhotra, IA Clark, Innocent Valéa, J Ismaili, J Riopel, J Zhu, JY Le Hesran, K Broen, K Brustoski, K Derra, K Gbédandé, K Takeda, KE Lyke, KK Smolen, KL Flanagan, KR Dobbs, L Maródi, L Maródi, LK Erdman, LP Breitling, Luc Kestens, M Bauer, M Liu, M Prahl, M. Athanase Somé, Maminata Coulibaly-Traoré, MG Netea, MM Stevenson, N Fievet, NG Schwarz, NH Hunt, O Defawe, O Levy, O Levy, O Levy, O Levy, P Aaby, P Gottschalk, P Ringwald, Petra F. Mens, RT Gazzinelli, Ruth Aguilar, S Burl, S Esposito, S Metenou, S Scott, Susana Scott, T Yoshimoto, TK Mutabingwa, V Jain, WR Weiss, Y Benjamini   +92 more
core   +1 more source

Unravelling the biochemical aspects of the interaction between ticks and Leishmania using a tick cell line

Medical and Veterinary Entomology, Volume 40, Issue 2, Page 350-359, June 2026.
Leishmania infantum propagated in IDE8 tick cell line in vitro. L. infantum reduces tick cell viability and induces reactive oxygen species production. Lipidic profile of IDE8 tick cell line is altered during Leishmania infection. Abstract Leishmaniasis comprises a group of vector‐borne neglected tropical diseases caused by species of the obligatory ...
Beatriz Filgueiras Silvestre, Karoline dos Anjos Lima, Fernanda de Paula Pepino, Daniela Cosentino‐Gomes, Adivaldo Fonseca, Lesley Bell‐Sakyi, Georgia Correa Atella, Lucia H. Pinto‐da‐Silva   +7 more
wiley   +1 more source

Preparation of azide biosynthetic surrogates of myo-Inositol [PDF]

, 2015
As a prelude to biomolecular incorporation studies, practical routes to a series of four regioisomeric azido-deoxy derivatives of inositol that mimic the natural myo-stereochemistry are described.
Agranoff, Angyal, Angyal, Angyal, Anilkumar, Baker, Baker, Ballereau, Banerjee, Bruzik, Cao, Chen, Collins, De Almeida, Desai, Dreef, Estevez, Fabris, Gigg, Gurale, Hammond, Jiang, Johnson, Johnson, Lee, Leiserow, Lin, Lu, Markus R. Wenk, Martin, Martin J. Lear, Mayer, Murali, Ozaki, Paulick, Podeschwa, Praveen, Riley, Riley, Rudolf, Sandip Pasari, Sanfilippo, Serrano, Shareef M. Ismail, Shears, Sureshan, Sureshan, Sureshan, Sureshan, Sureshan, Suzuki, Tagliaferri, Vacca, van Dijkum, Wang   +54 more
core   +1 more source

Rhamnogalacturonan‐II Dimerisation Reinforces Salt Resistance in Sugar Beet

Plant, Cell &Environment, Volume 49, Issue 6, Page 3082-3100, June 2026.
ABSTRACT Salinity stress predominantly affects negatively charged cell wall polymers, for example, pectin. Excess Na+ ions interact physically and affect growth in stress‐sensitive plants. However, the salinity resistance of sugar beet cell walls remains unclear.
Shah Newaz Chowdhury, Lukas Pfeifer, Kim‐Kristine Mueller, Sazzad Hossain, Birgit Classen, Karl Hermann Mühling   +5 more
wiley   +1 more source

Membrane plasmalogen composition and cellular cholesterol regulation: a structure activity study [PDF]

, 2010
Background Disrupted cholesterol regulation leading to increased circulating and membrane cholesterol levels is implicated in many age-related chronic diseases such as cardiovascular disease (CVD), Alzheimer's disease (AD), and cancer.
Rishikesh Mankidy, Pearson WK Ahiahonu, Hong Ma, Dushmanthi Jayasinghe, Shawn A Ritchie, Mohamed A Khan, Khine K Su-Myat, Paul L Wood, Dayan B Goodenowe   +8 more
core   +2 more sources

Real‐World Effectiveness and Safety of Ravulizumab in Patients With Paroxysmal Nocturnal Hemoglobinuria: Evidence From the International PNH Registry

American Journal of Hematology, Volume 101, Issue 5, Page 939-948, May 2026.
ABSTRACT Ravulizumab, a second‐generation complement component 5 inhibitor (C5i) derived from eculizumab, with improved pharmacokinetics, is the current standard‐of‐care treatment for patients with paroxysmal nocturnal hemoglobinuria (PNH), where available.
Alexander Röth, Christopher J. Patriquin, Jeff Szer, Louis Terriou, Ami S. Patel, Jesse Metzger, Philippe Gustovic, Jun‐ichi Nishimura, Robert A. Brodsky   +8 more
wiley   +1 more source

Communication between Toxoplasma gondii and its host: impact on parasite growth, development, immune evasion, and virulence [PDF]

, 2009
Toxoplasma gondii is an obligate intracellular protozoan parasite that can infect most warm-blooded animals and cause severe and life-threatening disease in developing fetuses and in immune-compromised patients.
Blader, Ira J., Saeij, Jeroen
core   +2 more sources

Computational Design of an mRNA Vaccine Targeting LRP6 for Triple‐Negative Breast Cancer Therapy

Cancer Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background Triple‐negative breast cancer (TNBC) presents a poorer prognosis than other breast cancer subtypes, attributed to its aggressive nature and the lack of specific therapeutic interventions. TNBC has high recurrence rates and limited survival despite current therapies, emphasizing the critical need for improved treatment options.
Pooriya Teimoori, Mohammadreza Heidari
wiley   +1 more source

Fluorine‐18‐Labeled Nucleotide Analogs Targeting Ecto‐5'‐Nucleotidase (CD73) for Positron Emission Tomography Imaging of Solid Tumors

Angewandte Chemie, Volume 138, Issue 17, 20 April 2026.
Fluorine‐18‐labeled CD73 inhibitor [18F]PSB‐19427 enables noninvasive PET mapping of CD73 overexpression in triple‐negative breast (TNBC) and pancreatic cancer. For [18F]PSB‐19427, specific binding in human tumor tissues, favorable biodistribution with prolonged blood retention, robust tumor uptake, and superiority to [18F]FDG in a TNBC model ...
Clemens Dobelmann, Constanze C. Schmies, Georg Wilhelm Rolshoven, Mirko Scortichini, Stefan Wagner, Andreas Isaak, Riham M. Idris, Jennifer Dabel, Lucie Grey, Karolina Losenkova, Susanne Moschütz, Haneen Al Hroub, Antje Keim, Sandra Höppner, Jouko Sandholm, Pia Boström, Maija Hollmén, Norbert Sträter, Sven Hermann, Gennady G. Yegutkin, Kenneth A. Jacobson, Sonja Schelhaas, Christa E. Müller, Anna Junker   +23 more
wiley   +2 more sources

Anopheles stephensi p38 MAPK signaling regulates innate immunity and bioenergetics during Plasmodium falciparum infection. [PDF]

, 2015
BackgroundFruit flies and mammals protect themselves against infection by mounting immune and metabolic responses that must be balanced against the metabolic needs of the pathogens.
Aguirre, Alejandro, Cheung, Kong, Drexler, Anna, Eigenheer, Richard, Giulivi, Cecilia, Glennon, Elizabeth KK, Klyver, John M, Lewis, Edwin E, Luckhart, Shirley, Napoli, Eleonora, Pakpour, Nazzy, Phinney, Brett S, Surachetpong, Win, Wang, Bo   +13 more
core   +1 more source