Results 81 to 90 of about 2,358 (202)
Emerging Roles of Adenosine Metabolism in Astrocytes During Brain Injury
CNS Neuroscience &Therapeutics, Volume 32, Issue 5, May 2026.Adenosine, as a key metabolic and neurotransmitter in the brain, has become an important therapeutic target for improving the efficacy of immunotherapy for stroke. However, gaps in knowledge about its metabolic pathways have become a key factor limiting its clinical translation.
Shu Zhu +4 more
wiley +1 more source
Molecular Genetics &Genomic Medicine, Volume 14, Issue 5, May 2026.We report two young children with severe hypertriglyceridemia lacking monogenic causes. Both were ANA‐positive, with confirmed anti‐GPIHBP1 antibodies. Immunosuppressive therapy (hydroxychloroquine ± prednisolone) effectively reduced triglycerides. GPIHBP1 autoantibody‐related hypertriglyceridemia is an important pediatric cause, requiring accurate ...
Rai‐Hseng Hsu +4 more
wiley +1 more source
Lipidomics in Health and Diseases - Beyond the Analysis of Lipids [PDF]
, 2014 published_or_final_versio
Fan, P, Li, M, Wang, Y
core +1 more source
Evolutionary Applications, Volume 19, Issue 5, May 2026.ABSTRACT Crustaceans, such as shrimp and crabs, are pivotal to global aquaculture, yet their productivity is severely impacted by low‐temperature stress. This study employs comparative transcriptomic and genomic analyses to elucidate the molecular mechanisms underlying crustacean responses to cold stress across five economically significant species ...
Ying Chen +7 more
wiley +1 more source
Activin A: its role and involvement in inflammatory diseases [PDF]
, 2015 Activin proteins are members of the transforming growth factor-β family. Activin A is involved in several biological responses including wound repair, cell death, proliferation and differentiation of many cell types.
Basir, Rusliza +4 more
core
Insights into genomics of salt stress response in rice [PDF]
, 2013 Plants, as sessile organisms experience various abiotic stresses, which pose serious threat to crop production. Plants adapt to environmental stress by modulating their growth and development along with the various physiological and biochemical changes ...
Hojin Ryu +4 more
core +1 more source
CD24 in Melanoma: Biomarker, Innate Immune Checkpoint and Emerging Therapeutic Target
Experimental Dermatology, Volume 35, Issue 5, May 2026.ABSTRACT Immune checkpoint inhibitors have transformed the treatment of advanced melanoma, yet many patients develop primary or acquired resistance. Although most work has focused on adaptive checkpoints (PD‐1 and CTLA‐4), accumulating evidence implicates innate immune suppression and stem‐like, drug‐resistant melanoma cell states.
Claudia Lasalle +6 more
wiley +1 more source
The Hemoprotein Hhy1 Promotes Heme‐Dependent Catalase Activity of Ctt1
Molecular Microbiology, Volume 125, Issue 5, Page 389-411, May 2026.A Schizosaccharomyces pombe strain deficient in heme (hem1Δ) and siderophore (Fc) biosynthesis, as well as high‐affinity iron (Fe) uptake (blue), was used to uncover the hemoprotein Hhy1 that promotes the heme‐dependent activity of the catalase Ctt1. In contrast, hhy1Δ cells exhibit reduced Ctt1 activity and increased sensitivity to oxidative stress ...
Tobias Vahsen +3 more
wiley +1 more source
Secretory pathway of trypanosomatid parasites [PDF]
, 2002 The Trypanosomatidae comprise a large group of parasitic protozoa, some of which cause important diseases in humans. These include Tryanosoma brucei (the causative agent of African sleeping sickness and nagana in cattle), Trypanosoma cruzi (the causative
McConville, Malcolm J. +3 more
core +1 more source
AGP and EXO‐LIKE genes promote brassinosteroid‐dependent anisotropic growth
New Phytologist, Volume 250, Issue 4, Page 2384-2398, May 2026.Summary The brassinosteroid pathway promotes anisotropic cell expansion; however, the effectors in this process remain unclear. Candidates include ARABINOGALACTAN PROTEIN (AGP) genes, which are prominent brassinosteroid‐responsive transcriptional targets, and EXORDIUM (EXO)‐LIKE (EXL) genes.
Daria Novikova +8 more
wiley +1 more source