ABSTRACT The plant endomembrane system and vesicle trafficking are central to plant immunity, mediating the targeted delivery and recycling of defence molecules during pathogen attack. Here, we investigated the functional role of soybean Vacuole Membrane Protein 1 (GmVMP1) in mediating resistance against soybean cyst nematode (SCN, Heterodera glycines).
Tracy E. Hawk +15 more
wiley +1 more source
Mapping condition-dependent regulation of metabolism in yeast through genome-scale modeling [PDF]
Background: The genome-scale metabolic model of Saccharomyces cerevisiae, first presented in 2003, was the first genome-scale network reconstruction for a eukaryotic organism.
Bordel, Sergio +3 more
core +1 more source
Glycosylphosphatidylinositol (GPI)-Anchored Proteins.
From the numerous studies developed at the last quarter of the 20th century, glycosylphosphatidylinositol (GPI) anchor has been established as a unique mode of protein binding to the plasma membrane. The core structure of this anchor consists of ethanolamine phosphate, trimannoside, glucosamine and inositol phospholipid in this order.
openaire +3 more sources
The Critical Role of GALNTs‐Regulated O‐GalNAc Glycosylation in Cancer Malignancy
The GALNT family initiates mucin‐type O‐GalNAc glycosylation in the Golgi apparatus and how regulatory mechanisms, including GALNT relocalization and microRNA control, modulate this process. Dysregulated O‐GalNAc glycosylation alters key cellular behaviors and promotes cancer malignancy, highlighting its relevance to tumor progression as well as its ...
Jiahao Liu +7 more
wiley +1 more source
Interactions of human galectins with Trypanosoma cruzi: binding profile correlate with genetic clustering of lineages [PDF]
This is a pre-copyedited, author-produced PDF of an article accepted for publication in Glycobiology following peer review. The version of record Pineda, M.A. et al.
Bonay, Pedro +5 more
core +2 more sources
GPI anchors: Regulated as needed. [PDF]
Aguilera-Romero A, Muñiz M.
europepmc +1 more source
Enhanced transmission of malaria parasites to mosquitoes in a murine model of type 2 diabetes [PDF]
core +1 more source
Glimepiride protects neurons against amyloid-beta-induced synapse damage [PDF]
Bate, C +5 more
core +2 more sources
IL-27 receptor signaling regulates CD4+ T cell chemotactic responses during infection.
IL-27 exerts pleiotropic suppressive effects on naive and effector T cell populations during infection and inflammation. Surprisingly, however, the role of IL-27 in restricting or shaping effector CD4(+) T cell chemotactic responses, as a mechanism to ...
Ana Villegas-Mendez +11 more
core +1 more source
Case report: Immune pressure on hematopoietic stem cells can drastically expand glycosylphosphatidylinositol-deficient clones in paroxysmal nocturnal hemoglobinuria. [PDF]
Shingai N +11 more
europepmc +1 more source

