Results 191 to 200 of about 26,147 (300)

Post‐Translational Modifications of Key Proteins in Hematologic Malignancies: Carcinogenic Mechanisms, Biomarker Potential, and New Therapeutic Strategies

open access: yesiLABMED, Volume 4, Issue 2, Page 91-107, June 2026.
This article reviews the pivotal role of post‐translational modifications of proteins in the development and progression of hematologic malignancies, and explores their clinical translation potential as novel biomarkers and therapeutic targets. ABSTRACT Post‐translational modifications (PTMs) of proteins have emerged as critical regulators in the ...
Yuxuan Han   +6 more
wiley   +1 more source

Genomic and Transcriptomic Insights Into Salinity Tolerance in Dry Pea

open access: yesLegume Science, Volume 8, Issue 2, June 2026.
ABSTRACT Salinity is a major crop production constraint in dry pea (Pisum sativum L.), making the development of salt‐tolerant varieties essential to improve crop productivity and land‐use efficiency. The genetic mechanisms of salt tolerance in dry pea are largely unknown, and research on salt‐tolerant genes is limited.
Shailesh Raj Acharya   +11 more
wiley   +1 more source

Genome‐Wide In Silico Analysis of the Type VI Secretion System (T6SS) Within the Morganella Genus

open access: yesMicrobiologyOpen, Volume 15, Issue 3, June 2026.
▪ Species‐specific T6SS patterns among Morganella genus (M. morganii and M. sibonii). ▪ Only one‐third of M. morganii isolates haboured a T6SS. ▪ All M. sibonii possess four T6SS clusters. ▪ M. sibonii exhibited a wide diversity of effectors compared to M. morganii.
Mathilde Duque   +4 more
wiley   +1 more source

Integrative Proteogenomic Characterization of Left‐Sided and Right‐Sided Colorectal Cancer

open access: yesMedComm, Volume 7, Issue 6, June 2026.
This study performed whole‐exome sequencing, proteomic, and phosphoproteomic analysis on 80 pairs of tumor tissues and matched normal adjacent tissues from colorectal cancer patients. The integrated proteogenomic study provides a comprehensive and nuanced understanding of the molecular heterogeneity between left‐ and right‐sided colorectal cancer ...
An Huang   +11 more
wiley   +1 more source

A Near Telomere-to-Telomere Genome of Belamcanda chinensis Provides Insights Into Genome Evolution and the Biosynthesis of Characteristic Isoflavones. [PDF]

open access: yesPlant Biotechnol J
ABSTRACT Belamcanda chinensis is a non‐leguminous medicinal plant rich in bioactive isoflavones; however, the lack of a high‐quality reference genome has limited elucidation of its isoflavone biosynthetic and modification network. Here, we present the first near telomere‐to‐telomere genome assembly of B.
Wang YY   +10 more
europepmc   +2 more sources

Advances in Research on the Anti‐Tuberculosis Effects of Active Components in Chinese Herbal Medicine

open access: yesMedComm – Future Medicine, Volume 5, Issue 2, June 2026.
This review summarizes how active constituents derived from Chinese herbal medicine exert anti‐tuberculosis (TB) effects via immunomodulation, direct inhibition of pathogens, and antioxidant activity. This synergistic, multi‐pathway mechanism highlights their potential as promising therapeutic candidates and adjunctive treatments against drug‐resistant
Qianqian Zhang   +8 more
wiley   +1 more source

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