Identification and Functional Analysis of Two UGT84 Glycosyltransferases in Flavonoid Biosynthesis of <i>Carthamus tinctorius</i>. [PDF]
Ren C +8 more
europepmc +1 more source
CD24 in Melanoma: Biomarker, Innate Immune Checkpoint and Emerging Therapeutic Target
ABSTRACT Immune checkpoint inhibitors have transformed the treatment of advanced melanoma, yet many patients develop primary or acquired resistance. Although most work has focused on adaptive checkpoints (PD‐1 and CTLA‐4), accumulating evidence implicates innate immune suppression and stem‐like, drug‐resistant melanoma cell states.
Claudia Lasalle +6 more
wiley +1 more source
Maternal-Child Blood Group Discordance and Severity of Congenital Heart Disease: Insights From a Tertiary Referral Study. [PDF]
Ahamad S, Tulsi A, Sharma A, Kukshal P.
europepmc +1 more source
ABSTRACT This study presents the first description and characterisation of Lactococcus garvieae isolated from diseased European sea bass (Dicentrarchus labrax) farmed in Spain. During autumn 2023, two fish farms were affected by infectious outbreaks causing moderate cumulative fish mortality (5%–10%). Diseased fish showed clinical signs of haemorrhagic
Belén Fouz +6 more
wiley +1 more source
Halophytic <i>C</i>‑Glycosyltransferases Enable <i>C</i>‑Glycosylation in Organic Solvents. [PDF]
Kırtel O +3 more
europepmc +1 more source
AGP and EXO‐LIKE genes promote brassinosteroid‐dependent anisotropic growth
Summary The brassinosteroid pathway promotes anisotropic cell expansion; however, the effectors in this process remain unclear. Candidates include ARABINOGALACTAN PROTEIN (AGP) genes, which are prominent brassinosteroid‐responsive transcriptional targets, and EXORDIUM (EXO)‐LIKE (EXL) genes.
Daria Novikova +8 more
wiley +1 more source
Multi-omics analyses of Dracocephalum moldavica L. reveal two flavonoid glycosyltransferases in tilianin biosynthesis. [PDF]
Zhao Q, Zhang X, Wang W, Yu H, Wang Z.
europepmc +1 more source
ABSTRACT Low temperature is a critical abiotic stress that imposes major constraints on the sustainable development of the fruit tree industry. Although exogenous dopamine has been shown to enhance cold tolerance in plants, its molecular mechanisms in apple (Malus domestica) remain poorly understood.
Kexin Tan +9 more
wiley +1 more source
Programmable saponin biosynthesis from gene networks to predictive biomanufacturing. [PDF]
Wang Y +6 more
europepmc +1 more source
Rewiring Steroidal Metabolic Pathways for Diosgenin Production in Solanum nigrum
ABSTRACT Diosgenin is a key starting material for the synthesis of steroidal drugs, such as corticosteroids and sex hormones. While the primary commercial source of diosgenin is the tubers of Dioscorea spp., identifying alternative plant hosts capable of diosgenin biosynthesis could enhance its production.
Jongbu Lim +16 more
wiley +1 more source

