Results 211 to 220 of about 38,132 (292)

CD24 in Melanoma: Biomarker, Innate Immune Checkpoint and Emerging Therapeutic Target

open access: yesExperimental Dermatology, Volume 35, Issue 5, May 2026.
ABSTRACT Immune checkpoint inhibitors have transformed the treatment of advanced melanoma, yet many patients develop primary or acquired resistance. Although most work has focused on adaptive checkpoints (PD‐1 and CTLA‐4), accumulating evidence implicates innate immune suppression and stem‐like, drug‐resistant melanoma cell states.
Claudia Lasalle   +6 more
wiley   +1 more source

First Description and Characterisation of Lactococcus garvieae Strains Causing Septicaemic Disease in Farmed Sea Bass (Dicentrarchus labrax; Linnaeus) in Spain

open access: yesJournal of Fish Diseases, Volume 49, Issue 5, May 2026.
ABSTRACT This study presents the first description and characterisation of Lactococcus garvieae isolated from diseased European sea bass (Dicentrarchus labrax) farmed in Spain. During autumn 2023, two fish farms were affected by infectious outbreaks causing moderate cumulative fish mortality (5%–10%). Diseased fish showed clinical signs of haemorrhagic
Belén Fouz   +6 more
wiley   +1 more source

AGP and EXO‐LIKE genes promote brassinosteroid‐dependent anisotropic growth

open access: yesNew Phytologist, Volume 250, Issue 4, Page 2384-2398, May 2026.
Summary The brassinosteroid pathway promotes anisotropic cell expansion; however, the effectors in this process remain unclear. Candidates include ARABINOGALACTAN PROTEIN (AGP) genes, which are prominent brassinosteroid‐responsive transcriptional targets, and EXORDIUM (EXO)‐LIKE (EXL) genes.
Daria Novikova   +8 more
wiley   +1 more source

The MdICE1/MdFAMA‐MdTYDC Transcriptional Module Confers Cold Tolerance by Regulating Dopamine Metabolism in Apple

open access: yesPlant Biotechnology Journal, Volume 24, Issue 5, Page 3012-3031, May 2026.
ABSTRACT Low temperature is a critical abiotic stress that imposes major constraints on the sustainable development of the fruit tree industry. Although exogenous dopamine has been shown to enhance cold tolerance in plants, its molecular mechanisms in apple (Malus domestica) remain poorly understood.
Kexin Tan   +9 more
wiley   +1 more source

Programmable saponin biosynthesis from gene networks to predictive biomanufacturing. [PDF]

open access: yesFront Plant Sci
Wang Y   +6 more
europepmc   +1 more source

Rewiring Steroidal Metabolic Pathways for Diosgenin Production in Solanum nigrum

open access: yesPlant Biotechnology Journal, Volume 24, Issue 5, Page 3032-3047, May 2026.
ABSTRACT Diosgenin is a key starting material for the synthesis of steroidal drugs, such as corticosteroids and sex hormones. While the primary commercial source of diosgenin is the tubers of Dioscorea spp., identifying alternative plant hosts capable of diosgenin biosynthesis could enhance its production.
Jongbu Lim   +16 more
wiley   +1 more source

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