Biomolecules, 2023 Urine is considered an outstanding biological fluid for biomarker discovery, reflecting both systemic and urogenital physiology. However, analyzing the N-glycome in urine in detail has been challenging due to the low abundance of glycans attached to ...
Hend Zedan +4 more
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Mass Spectrometry Imaging for Glycome in the Brain
Frontiers in Neuroanatomy, 2021 Glycans are diverse structured biomolecules that play crucial roles in various biological processes. Glycosylation, an enzymatic system through which various glycans are bound to proteins and lipids, is the most common and functionally crucial post ...
Md. Mahmudul Hasan +11 more
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Immunoglobulin G and plasma glycome in early rheumatoid arthritis differ from matched controls and link less fat-free mass to an accelerated aging phenotype: an exploratory study [PDF]
Arthritis Research & TherapyBackground In patients with rheumatoid arthritis (RA), the immunoglobulin G (IgG) glycome is altered and characterized by decreased galactosylation. The goals of our exploratory study were to identify (1) alterations in the IgG and plasma glycome and ...
Sidra W. Hashmi +13 more
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The ‘sugar’ side of extracellular vesicle—glycome: a panorama from basic characteristics, deciphering technologies, functions, to applications [PDF]
Journal of NanobiotechnologyBackground Extracellular vesicles (EVs) represent a heterogeneous group of lipid-enclosed vesicular structures. Despite their tiny bodies, EVs harbor a rich repertoire of functional molecular entities.
Yufei Yan +5 more
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Age-Related Changes in Serum N-Glycome in Men and Women—Clusters Associated with Comorbidity
Biomolecules, 2023 (1) Aim: To describe, in a general adult population, the serum N-glycome in relation to age in men and women, and investigate the association of N-glycome patterns with age-related comorbidity; (2) Methods: The serum N-glycome was studied by hydrophilic ...
Óscar Lado-Baleato +9 more
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Interstitial fluid N-glycans serve as a proxy for serum biomarker discovery in a pilot study [PDF]
Scientific ReportsProtein glycosylation is the most prevalent post-translational modification and is known to undergo profound alterations in disease. While serum N-glycosylation has been extensively studied, interstitial fluid is gaining prominence as a minimally ...
Radka Saldova +4 more
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Multiomics Profiling Reveals Signatures of Dysmetabolism in Urban Populations in Central India
Microorganisms, 2021 Background: Non-communicable diseases (NCDs) have become a major cause of morbidity and mortality in India. Perturbation of host–microbiome interactions may be a key mechanism by which lifestyle-related risk factors such as tobacco use, alcohol ...
Tanya M. Monaghan +22 more
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Possible role of sialylation of retinal protein glycans in the regulation of electroretinogram response in mice [PDF]
International Journal of Ophthalmology, 2017 AIM: To evaluate if the nature, degree and extent of Siaα2-3-/Siaα2-6-sialylation of retinal protein glycans plays a possible role in the development and regulation of electroretinogram response (ERG) in mice.
Satpal Ahuja
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Glycobiology of Cancer: Sugar Drives the Show
Medicines, 2022 Cancer development and progression is associated with aberrant changes in cellular glycosylation. Cells expressing altered glycan-structures are recognized by cells of the immune system, favoring the induction of inhibitory immune processes which ...
Jhenifer Santos dos Reis +12 more
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Sensors, 2021 I conducted this study to develop an improved method for glycome detection using fluorescent magnetic beads, whose surfaces were modified using lectins, for the highly sensitive detection of saccharides or glycoproteins via fluorescence quenching using a
Yoshio Suzuki
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