Results 21 to 30 of about 5,978 (206)

Effects of low-calorie and different weight-maintenance diets on IgG glycome composition

Frontiers in Immunology, 2022
Obesity-induced inflammation activates the adaptive immune system by altering immunoglobulin G (IgG) glycosylation in a way to produce more proinflammatory antibodies. The IgG glycome has already been well studied, and its alterations are correlated with
Helena Deriš, Petra Tominac, Frano Vučković, Nina Briški, Arne Astrup, Ellen E. Blaak, Gordan Lauc, Gordan Lauc, Ivan Gudelj, Ivan Gudelj   +9 more
doaj   +2 more sources

Fast and Simple Protocol for N-Glycome Analysis of Human Blood Plasma Proteome

Biomolecules
N-glycome analysis of individual proteins and tissues is crucial for fundamental and applied biomedical research and medical diagnosis and plays an important role in the evaluation of the quality of biopharmaceutical and biotechnological products.
Denis E. Maslov, Anna N. Timoshchuk, Alexander A. Bondar, Maxim P. Golubev, Anna G. Soplenkova, Maja Hanic, Sodbo Z. Sharapov, Olga N. Leonova, Yurii S. Aulchenko, Tatiana S. Golubeva   +9 more
doaj   +2 more sources

Single-Cell Glycomics of the Pancreatic Tumor Microenvironment: Technologies, Glyco-Immune Checkpoints, and Tumor-Immune Communication. [PDF]

Adv Biol (Weinh)
Single‐cell glycomics reveals how epithelial–mesenchymal transition (EMT) remodels the cancer cell glycome and reshapes communication with immune cells. Emerging technologies, including scGR‐seq and GlycoChat, uncover glyco‐immune checkpoints in pancreatic cancer, highlighting glycans as active regulators of tumor–immune interactions and providing a ...
Anh DXT, Tateno H.
europepmc   +2 more sources

Imaging the glycome [PDF]

Proceedings of the National Academy of Sciences, 2009
Molecular imaging enables visualization of specific molecules in vivo and without substantial perturbation to the target molecule's environment. Glycans are appealing targets for molecular imaging but are inaccessible with conventional approaches.
Scott T, Laughlin, Carolyn R, Bertozzi
openaire   +2 more sources

Shotgun glycomics: a microarray strategy for functional glycomics [PDF]

Nature Methods, 2010
Major challenges of glycomics are to characterize a glycome and identify functional glycans as ligands for glycan-binding proteins (GBPs). To address these issues we developed a general strategy termed shotgun glycomics. We focus on glycosphingolipids (GSLs), a class of glycoconjugates that is challenging to study, recognized by toxins, antibodies and ...
Song, Xuezheng, Lasanajak, Yi, Xia, Baoyun, Heimburg-Molinaro, Jamie, Rhea, Jeanne M., Ju, Hong, Zhao, Chunmei, Molinaro, Ross J., Cummings, Richard D., Smith, David F.   +9 more
openaire   +2 more sources

Membrane glycome is impacted by the cell culturing mode of neuroblastoma cells with differing migration and invasion potential

, 2022
Neuroblastoma is a highly metastatic childhood cancer for which studies indicate an association between protein glycosylation and tumor behavior. However, there is a lack of detailed glycome analysis on neuroblastoma cells that have varying metastatic ...
Packer, Nicolle H, Sumer-Bayraktar, Zeynep, Byrne, Frances L, Fife, Christopher M, Kavallaris, Maria   +4 more
core   +1 more source

Serum N‑Glycome Characterization in Patients with Resectable Periampullary Adenocarcinoma

, 2015
Serum N-glycans are promising biomarkers for systemic disease states. Better understanding of the serum N-glycome of patients with resectable periampullary adenocarcinoma may identify novel prognostic markers for this disease.
Knut Jørgen Labori (1471054), Elin H. Kure (172834), Henning Stöckmann (1265331), Trond Buanes (1471057), Radka Saldova (452398), Ole Christian Lingjærde (14863), Inger Marie Bowitz Lothe (1471051), Pauline M. Rudd (1471060), Julian Hamfjord (172804), Vandana Sandhu (620290)   +9 more
core   +4 more sources

The N-Glycome to Differentiate Mesenchymal Stem Cells Upon Chondrogenic Differentiation, Dedifferentiation, and Senescence. [PDF]

Proteomics
ABSTRACT Mesenchymal stem cells (MSCs) are adult stem cells able to self‐renewal or differentiation into different cell types, including chondrocytes. N‐Glycans are post‐translational modifications of glycoproteins that contribute to vital cell functions.
Montacir H, Biskup K, Sittinger M, Tauber R, Blanchard V.   +4 more
europepmc   +2 more sources

Uukuniemi Phlebovirus assembly and secretion leave a functional imprint on the Virion Glycome [PDF]

, 2014
Uukuniemi virus (UUKV) is a model system for investigating the genus Phlebovirus of the Bunyaviridae. We report the UUKV glycome, revealing differential processing of the Gn and Gc virion glycoproteins.
Scrivens, JH, Crispin, Max, Huiskonen, JT, Scrivens, James H., Bitto, David, Crispin, Matthew, Harvey, David J, Bitto, D, Scrivens, James, Huiskonen, Juha T, Bowden, Thomas A, Crispin, M, Bowden, Thomas A., Scrivens, James H, Edgeworth, Matthew, Halldorsson, Steinar, Huiskonen, Juha T., Bonomelli, Camille, Edgeworth, M, Bowden, TA, Bonomelli, C, Harvey, David J., Harvey, DJ, Halldorsson, S   +23 more
core   +1 more source

Fucanomics and Galactanomics: Marine Distribution, Medicinal Impact, Conceptions, and Challenges

Marine Drugs, 2012
Glycomics turned out to be a very extensive project where its subdivision is consequently emerging. This is seen by the growing number of terminologies used to define subprojects concerning particular classes of bioactive carbohydrates.
Vitor H. Pomin
doaj   +1 more source