Results 21 to 30 of about 6,080 (220)
Possible role of sialylation of retinal protein glycans in the regulation of electroretinogram response in mice [PDF]
International Journal of Ophthalmology, 2017 AIM: To evaluate if the nature, degree and extent of Siaα2-3-/Siaα2-6-sialylation of retinal protein glycans plays a possible role in the development and regulation of electroretinogram response (ERG) in mice.
Satpal Ahuja
doaj +1 more source
Glycobiology of Cancer: Sugar Drives the Show
Medicines, 2022 Cancer development and progression is associated with aberrant changes in cellular glycosylation. Cells expressing altered glycan-structures are recognized by cells of the immune system, favoring the induction of inhibitory immune processes which ...
Jhenifer Santos dos Reis +12 more
doaj +1 more source
The Mannose Receptor Ligands and the Macrophage Glycome
Current Opinion in Structural Biology, 2022 A unique glycan binding protein expressed in macrophages and some types of other immune cells is the mannose receptor (MR, CD206). It is an endocytic, transmembrane protein with multiple glycan binding domains and different specificities in binding ...
R. Cummings
semanticscholar +1 more source
Mass Spectrometry Imaging for Glycome in the Brain
Frontiers in Neuroanatomy, 2021 Glycans are diverse structured biomolecules that play crucial roles in various biological processes. Glycosylation, an enzymatic system through which various glycans are bound to proteins and lipids, is the most common and functionally crucial post ...
Md. Mahmudul Hasan +11 more
doaj +1 more source
Trends in immunology, 2023 Glycans cover the surfaces of all mammalian cells through a process called glycosylation. Nearly all proteins and receptors that integrate the intricate series of co-stimulatory/inhibitory pathways of the immune system are glycosylated.
M. Vicente, E. Leite-Gomes, S. Pinho
semanticscholar +1 more source
Human-specific features and developmental dynamics of the brain N-glycome
Science Advances, 2023 Comparative “omics” studies have revealed unique aspects of human neurobiology, yet an evolutionary perspective of the brain N-glycome is lacking. We performed multiregional characterization of rat, macaque, chimpanzee, and human brain N-glycomes using ...
Thomas Stephen Klarić +19 more
semanticscholar +2 more sources
Association Between Human Gut Microbiome and N-Glycan Composition of Total Plasma Proteome
Frontiers in Microbiology, 2022 Being one of the most dynamic entities in the human body, glycosylation of proteins fine-tunes the activity of the organismal machinery, including the immune system, and mediates the interaction with the human microbial consortium, typically represented ...
Vyacheslav A. Petrov +14 more
doaj +1 more source
Rewiring of the N-Glycome with prostate cancer progression and therapy resistance
npj Precision Oncology, 2023 An understanding of the molecular features associated with prostate cancer progression (PCa) and resistance to hormonal therapy is crucial for the identification of new targets that can be utilized to treat advanced disease and prolong patient survival ...
W. Butler +11 more
semanticscholar +1 more source
Sensors, 2021 I conducted this study to develop an improved method for glycome detection using fluorescent magnetic beads, whose surfaces were modified using lectins, for the highly sensitive detection of saccharides or glycoproteins via fluorescence quenching using a
Yoshio Suzuki
doaj +1 more source
Molecular & Cellular Proteomics, 2023 The asialoglycoprotein receptor (ASGPR) and the mannose receptor C-type 1 (MRC1) are well known for their selective recognition and clearance of circulating glycoproteins.
M. Svecla +8 more
semanticscholar +1 more source