Results 41 to 50 of about 5,978 (206)

Association of Systemic Lupus Erythematosus With Decreased Immunosuppressive Potential of the IgG Glycome [PDF]

, 2015
Objective. Glycans attached to the Fc portion of IgG are important modulators of IgG effector functions. Interindividual differences in IgG glycome composition are large and they associate strongly with different inflammatory and autoimmune diseases ...
Guo XH, Stambuk J, Teruel M, Keser T, Song HC, Menni C, Cui LF, Spector TD, Pucic-Bakovic M, Gornik O, Wang W, Harjacek M, Zeng Q, McKeigue P, Gudelj I, Pons-Estel BA, Patrick AL, Zhou Y, Pezer M, Trbojevic-Akmacic I, Barrios C, Molokhia M, Alarcon-Riquelme M, Vuckovic F, Kristic J, Lauc G, Pavic T, Wang YX   +27 more
core   +3 more sources

Reduced colonic mucin degradation in breastfed infants colonized by Bifidobacterium longum subsp. infantis EVC001

FEBS Open Bio, 2018
Mucin glycoproteins play an important role in protecting the gut epithelium by keeping gut microbes from direct contact with the gut epithelium while allowing for diffusion of small molecules from the lumen to the epithelium.
Sercan Karav, Giorgio Casaburi, Steven A. Frese   +2 more
doaj   +1 more source

Alterations in the glycome after HDAC inhibition impact oncogenic potential in epigenetically plastic SW13 cells

BMC Cancer, 2019
Background Defects in the type and degree of cellular glycosylation impact oncogenesis on multiple levels. Although the type of glycosylation is determined by protein sequence encoded by the genome, the extent and modifications of glycosylation depends ...
McKale R. Montgomery, Elizabeth E. Hull
doaj   +1 more source

Glycoproteomic and glycomic databases [PDF]

Clinical Proteomics, 2014
Protein glycosylation serves critical roles in the cellular and biological processes of many organisms. Aberrant glycosylation has been associated with many illnesses such as hereditary and chronic diseases like cancer, cardiovascular diseases, neurological disorders, and immunological disorders. Emerging mass spectrometry (MS) technologies that enable
Baycin Hizal, Deniz, Wolozny, Daniel, Colao, Joseph, Jacobson, Elena, Tian, Yuan, Krag, Sharon S, Betenbaugh, Michael J, Zhang, Hui   +7 more
openaire   +2 more sources

Single cell surface glycome heterogeneity analysis of HEK293 cells by lectin-based flow cytometry

, 2023
reservedIl cambiamento di stato cellulare ha un profondo impatto sulla capacità delle singole cellule di subire un destino specifico. La microeterogeneità cellulare fornisce un adattamento all'ambiente e supporta funzioni robuste su diverse scale.
DISCONZI, GIADA
core  

Spatial and temporal diversity of glycome expression in mammalian brain

, 2020
Mammalian brain glycome remains a relatively poorly understood area compared to other large-scale "omics" studies, such as genomics and transcriptomics due to the inherent complexity and heterogeneity of glycan structure and properties.
Seungshin Ha, Hee-Sup Shin, Sabine Bahn, Jaekyung Yun, Seong-Wook Kim, Maree J. Webster, Jae-Han Kim, Heeyoun Hwang, Jong Shin Yoo, In Jung Ji, Dongtan Yin, Hyun Joo An, Jua Lee, Cynthia Shannon Weickert, Rudolf Grimm, Minsoo Kim, Sureyya Ozcan   +16 more
core   +1 more source

Epigenetic regulation of protein glycosylation

Biomolecular Concepts, 2010
Protein N-glycosylation is an ancient metabolic pathway that still exists in all three domains of life (Archaea, Bacteria and Eukarya). The covalent addition of one or more complex oligosaccharides (glycans) to protein backbones greatly diversifies their
Zoldoš Vlatka, Grgurević Srđana, Lauc Gordan   +2 more
doaj   +1 more source

Precision N-glycoproteomics reveals the essential role of the extracellular matrix in tropomyosin allergy in a mouse model

Food Science and Human Wellness
Approximately 2.5% of the global population experience allergic reactions to seafood, making it one of the most prevalent and life-threatening allergies.
Guirong Liu, Qianwei Wang, Yibo Luo, Lijuan Sun, Ruolin Song, Huilian Che, Changqi Liu, Xiaohui Guo   +7 more
doaj   +1 more source

Glycogene Expression Profile of Human Limbal Epithelial Cells with Distinct Clonogenic Potential

Cells, 2022
Glycans function as valuable markers of stem cells but also regulate the ability of these cells to self-renew and differentiate. Approximately 2% of the human genome encodes for proteins that are involved in the biosynthesis and recognition of glycans ...
Damien Guindolet, Ashley M. Woodward, Eric E. Gabison, Pablo Argüeso   +3 more
doaj   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source