Results 61 to 70 of about 6,080 (220)

Glycomics

, 2011
Paramount to our understanding of carbohydrates in biology has been the development of methods for analyzing and characterizing the essential features of glycans. This has resulted in a comprehensive appreciation for the various roles of glycans and the pathways associated with their synthesis.
Cosgrave, E.F.J., Struwe, Weston B., Kattla, J.J., Campbell, Matthew P., Wormald, M.R., Rudd, P.   +5 more
openaire   +3 more sources

Glycomics and disease markers [PDF]

Current Opinion in Chemical Biology, 2009
Glycomics is the comprehensive study of all glycans expressed in biological systems. The biosynthesis of glycan relies on a number of highly competitive processes involving glycosyl transferases. Glycosylation is therefore highly sensitive to the biochemical environment and has been implicated in many diseases including cancer.
Hyun Joo, An, Scott R, Kronewitter, Maria Lorna A, de Leoz, Carlito B, Lebrilla   +3 more
openaire   +2 more sources

The effect of blood sampling and preanalytical processing on human N-glycome.

PLoS ONE, 2018
Glycome modulations have been described in the onset and progression of many diseases. Thus, many studies have proposed glycans from blood glycoproteins as disease markers.
Tereza Dědová, Detlef Grunow, Kai Kappert, Dagmar Flach, Rudolf Tauber, Véronique Blanchard   +5 more
doaj   +1 more source

IgG N-glycosylation from Patients with Pemphigus Treated with Rituximab

Biomedicines, 2022
Pemphigus is a life-threatening auto-immune blistering disease of the skin and mucous membrane that is caused by the production of auto-antibodies (auto-Abs) directed against adhesion proteins: desmoglein 1 and 3.
Guillaume Font, Marie-Laure Walet-Balieu, Marie Petit, Carole Burel, Maud Maho-Vaillant, Vivien Hébert, Philippe Chan, Manuel Fréret, Olivier Boyer, Pascal Joly, Sébastien Calbo, Muriel Bardor, Marie-Laure Golinski   +12 more
doaj   +1 more source

Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág, Krisztián Márk Karvaly, Alexandra Molnár, Mirjam Balbisi, Júlia Németh, Lilla Turiák   +5 more
wiley   +1 more source

The Human Glycome Atlas project for cataloging all glycan-related omics data in human

Glycobiology
The Human Glycome Atlas (HGA) Project was launched in April 2023, spearheaded by three Japanese institutes: the Tokai National Higher Education and Research System, the National Institutes of Natural Sciences, and Soka University. This was the first time
Kiyoko F. Aoki-Kinoshita, Hiromune Ando, Kiyohiko Angata, Morihisa Fujita, Jun-ichi Furukawa, Hiroyuki Kaji, Koichi Kato, K. Kitajima, Yasuhiko Kizuka, Yusuke Matsui, Kazuki Nakajima, Shoko Nishihara, Tetsuya Okajima, Kazuma Sakamoto, C. Sato, Morten Thaysen-Andersen, Akira Togayachi, Hirokazu Yagi, Kenji Kadomatsu   +18 more
semanticscholar   +1 more source

Role of milk glycome in prevention, treatment, and recovery of COVID-19

Frontiers in Nutrition, 2022
Milk contains all essential macro and micro-nutrients for the development of the newborn. Its high therapeutic and antimicrobial content provides an important function for the prevention, treatment, and recovery of certain diseases throughout life.
Merve Kaplan, A. S. Şahutoğlu, Sümeyye Sarıtaş, Hatice Duman, Ayşe Arslan, Burcu Pekdemir, S. Karav   +6 more
semanticscholar   +1 more source

GlycoChat Uncovers Glycan–Lectin Circuits in the Tumor Microenvironment of Pancreatic Cancer

Advanced Science
Aberrant glycosylation is a hallmark of cancer progression, yet its functional implications within the tumor microenvironment (TME) remain poorly understood.
Dinh Xuan Tuan Anh, Sunanda Keisham, Arun Burramsetty, Lalhaba Oinam, Koichiro Kumano, Akihiro Kuno, Osamu Shimomura, Tatsuya Oda, Hiroaki Tateno   +8 more
doaj   +1 more source

The N‐Glycome to Differentiate Mesenchymal Stem Cells Upon Chondrogenic Differentiation, Dedifferentiation, and Senescence

PROTEOMICS, EarlyView.
ABSTRACT Mesenchymal stem cells (MSCs) are adult stem cells able to self‐renewal or differentiation into different cell types, including chondrocytes. N‐Glycans are post‐translational modifications of glycoproteins that contribute to vital cell functions.
Houda Montacir, Karina Biskup, Michael Sittinger, Rudolf Tauber, Véronique Blanchard   +4 more
wiley   +1 more source

The IgG glycome of SARS-CoV-2 infected individuals reflects disease course and severity

Frontiers in Immunology, 2022
Immunoglobulin G (IgG) antibodies play an important role in the immune response against viruses such as SARS-CoV-2. As the effector functions of IgG are modulated by N-glycosylation of the Fc region, the structure and possible function of the IgG N ...
Sterre L Siekman, T. Pongracz, Wenjun Wang, J. Nouta, P. Kremsner, P. V. da Silva-Neto, Meral Esen, A. Kreidenweiss, Jana Held, Á. A. Trapé, Rolf Fendel, I. K. F. de Miranda Santos, M. Wuhrer, Alessandro P. Jamille G M. Rita de C.C. Marcelo Victor A F. V de Amorim Argolo Barbieri Dias-Baruffi Bastos Bona   +13 more
semanticscholar   +1 more source