Results 51 to 60 of about 5,978 (206)
Glycomics and disease markers [PDF]
Current Opinion in Chemical Biology, 2009 Glycomics is the comprehensive study of all glycans expressed in biological systems. The biosynthesis of glycan relies on a number of highly competitive processes involving glycosyl transferases. Glycosylation is therefore highly sensitive to the biochemical environment and has been implicated in many diseases including cancer.
Hyun Joo, An +3 more
openaire +2 more sources
Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles
Mass Spectrometry Reviews, EarlyView.ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág +5 more
wiley +1 more source
, 2011 Paramount to our understanding of carbohydrates in biology has been the development of methods for analyzing and characterizing the essential features of glycans. This has resulted in a comprehensive appreciation for the various roles of glycans and the pathways associated with their synthesis.
Cosgrave, E.F.J. +5 more
openaire +3 more sources
Extending Tlusty's method to the glycome: Tuning the repertoire of glycan determinants [PDF]
, 2011 We apply Tlusty's information-theoretic analysis of the genetic code to the glycome, using a cognitive paradigm in which external information sources constrain and tune the glycan code error network, in the context of available metabolic energy. The
Rodrick Wallace, Deborah Wallace
core
N-glycome analysis in digestive system cancers
, 2014 N-glycome analysis in digestive system ...
Xin-Yun Xu (551338) +10 more
core +1 more source
Genetic control of N-glycosylation of human blood plasma proteins
Вавиловский журнал генетики и селекции, 2023 Glycosylation is an important protein modification, which influences the physical and chemical properties as well as biological function of these proteins.
S. Zh. Sharapov +2 more
doaj +1 more source
Peptide‐directed nanovehicles enabling tumor‐selective ROS amplification and antitumor immunity
VIEW, EarlyView.Cancer cells are vulnerable to oxidative stress, yet exploit immune tolerance to escape destruction. In contrast, their metabolic profile is markedly altered to support rapid proliferation, accompanied by elevated production of reactive oxygen species (ROS).
Manuela Calin +3 more
wiley +1 more source
Glycan Microarrays for Decoding the Glycome
, 2011 In the last decade, glycan microarrays have revolutionized the analysis of the specificity of glycan-binding proteins (GBPs), providing information that simultaneously illuminates the biology mediated by them and decodes the informational content of the ...
James C. Paulson, Cory D. Rillahan
core +1 more source
Determinants of Immunoglobulin‐G N‐Glycan Patterns in the Aging General Population
Allergy, EarlyView.The effect of demographic and lifestyle factors on IgG N‐glycosylation, which determines IgG's inflammatory response, remains poorly characterized. Aging, higher BMI, female sex, smoking, and heavy alcohol consumption are determinants of IgG N‐glycome patterns, which are indicative of inflammation. Women exhibit a distinct change in IgG N‐glycosylation
Samantha Leonard +10 more
wiley +1 more source
Chitinase-deficient strains maintained invasion defects for glycome analysis.
, 2022 Gentamicin protection assay of S. Typhimurium infected IPEC-1 cells (MOI:1000) done concurrently with infection for the glycome analysis. n = 2. Bars represent mean ± SD. (TIFF)
Jorge Mendez (80617) +11 more
core +1 more source